Results 121 to 130 of about 3,238,785 (313)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Differential patterns of cross-protection against antigenically distinct variants in small animal models of SARS-CoV-2 infection

npj Viruses
Continuous evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will likely necessitate periodic updates of vaccine composition. Based on a series of studies carried out in human ACE2 transgenic mice (K18-hACE2) and Syrian hamsters ...
Prabhuanand Selvaraj, Charles B. Stauft, Shufeng Liu, Kotou Sangare, Tony T. Wang   +4 more
doaj   +1 more source

Salted egg white derived-peptides VF-4 and DR-8 improve DSS-induced colitis in mice by inhibiting NF-κB/MAPK/PI3K-AKT signaling pathways and modulating gut microbiota composition

Food Science and Human Wellness
Inflammation underlies many chronic diseases, and inflammatory bowel disease (IBD) is a condition characterized by long-term inflammation of the gut. Egg whites have been shown to contain many beneficial active substances.
Na Zhou, Na Wu, Yao Yao, Shuping Chen, Mingsheng Xu, Zhongping Yin, Yan Zhao, Yonggang Tu   +7 more
doaj   +1 more source

Circular 64 [PDF]

, 1988
Treatment of Alaska-produced food products by ionizing radiation may benefit the seafood and agricultural industries and the Alaskan consumer. A feasibility study to evaluate the potential social and economic benefits and risks as well as the ...
Das, Debendra K., Hok, Charlotte I., Lewis, Carol E., Logan, Robert R., Swanson, Ruthann B., Workman, William G., Zarling, John P.   +6 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

The positioning of organic products: which way forward? [PDF]

, 2006
The current positioning of organic products is based on a segmentation approach that recognises the organic market basically as a (enlarging) niche.
Naspetti, Dr. Simona, Zanoli, Prof. Raffaele   +1 more
core  

Sustainable food production

Agrociencia Uruguay
Agroindustrial and domestic waste obtained from fruit and vegetable processing represents a nutritious, economical, and environmentally friendly raw material. These wastes have attracted attention because they are considered a good source of bioactive compounds such as polyphenols, carotenoids, and dietary fiber. Therefore, the combination of vegetable
Addí Rhode Navarro-Cruz, Obdulia Vera-López, Martin Lazcano­-Hernández, Daniel Juárez-Serrano, Ashuin Kammar-García, Ivan Cesar-Arteaga, Armando Cortés-Lozada, Araceli Toquero-Franco, Gladys Quezada-Figueroa, Orietta Segura-Badilla   +9 more
openaire   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source