Results 81 to 90 of about 3,201,295 (303)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

KEY DEVELOPMENTS IN THE FOOD DISTRIBUTION SYSTEM [PDF]

open access: yes
Many changes are occurring in food retailing. Forces driving these changes include the sales gains by supercenter, membership club, and convenience stores, the growing popularity of foodservice, the expansion of private label products (and the response ...
Larson, Ronald B.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Perceptions of nicotine harm among adults who use little cigars and cigarillos: A cross-sectional analysis of wave 7 of the Population Assessment of Tobacco and Health (PATH) Study 2022–2023

open access: yesTobacco Induced Diseases
Introduction Little is known about nicotine perceptions among people who use little cigars and cigarillos (LCCs). Nicotine perceptions may influence how people respond to changes in the tobacco marketplace, including changes that would result from ...
Amanda Fidalgo   +3 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

A neonatal mouse model of central nervous system infections caused by Coxsackievirus B5

open access: yesEmerging Microbes and Infections, 2018
As one of the key members of the coxsackievirus B group, coxsackievirus B5 (CV-B5) can cause many central nervous system diseases, such as viral encephalitis, aseptic meningitis, and acute flaccid paralysis.
Qunying Mao   +11 more
doaj   +1 more source

Hedonic Analysis of Sustainable Food Products [PDF]

open access: yes
hedonic, sustainable, sustainability, eggs, free-range, cage-free, Agribusiness, Q13,
Satimanon, Thasanee   +1 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

The effectiveness of instant “Basa Genep” seasoning and its impact on climate change [PDF]

open access: yesE3S Web of Conferences
“Basa Genep” spice is one of the traditional spices from Bali, representing local wisdom that needs to be preserved. This study aims to evaluate the effectiveness of the instant spice “Basa Genep” in enhancing the flavor and quality of various ...
Singapurwa Ni Made Ayu Suardani   +4 more
doaj   +1 more source

Rising demand for livestock products in India: nature, patterns and implications [PDF]

open access: yes
With a large population and recent growth in consumer income, India’s demand for food has increased. However, research continues to emphasise basic foods, and the demand for livestock products remains poorly understood. This study examines the demand for
Vasant, P. Ghandi, Zhang-Yue, Zhou
core   +1 more source

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