Results 81 to 90 of about 3,238,785 (313)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Perceptions of nicotine harm among adults who use little cigars and cigarillos: A cross-sectional analysis of wave 7 of the Population Assessment of Tobacco and Health (PATH) Study 2022–2023

open access: yesTobacco Induced Diseases
Introduction Little is known about nicotine perceptions among people who use little cigars and cigarillos (LCCs). Nicotine perceptions may influence how people respond to changes in the tobacco marketplace, including changes that would result from ...
Amanda Fidalgo   +3 more
doaj   +1 more source

Development and Validation of a Reporter-Cell-Line-Based Bioassay for Therapeutic Soluble gp130-Fc

open access: yesMolecules, 2019
Soluble glycoprotein 130 kDa (sgp130)-Fc fusion protein, an innovative therapeutic bio-macromolecular drug specifically targeting IL-6 trans-signaling, proved to have good potential for application in the treatment of chronic inflammatory diseases.
Lei Yu   +6 more
doaj   +1 more source

How is Modernity Accepted by Consumers with Respect to Traditional Food Products? The Case of Traceability [PDF]

open access: yes
Up till now, no researches have been done on consumers’ acceptability of new technical supporters of traceability, especially for traditional food products.
Giraud, Georges, Halawany, Rafia
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Rising demand for livestock products in India: nature, patterns and implications [PDF]

open access: yes
With a large population and recent growth in consumer income, India’s demand for food has increased. However, research continues to emphasise basic foods, and the demand for livestock products remains poorly understood. This study examines the demand for
Vasant, P. Ghandi, Zhang-Yue, Zhou
core   +1 more source

Volume Growth in Quality Food Firms – Lessons and Reflections from Norway [PDF]

open access: yes, 2013
A review of research on growth processes in quality food chains in Norway shows that only a few studies have focused on growth in such chains. Studies look at food businesses as the focal unit and discover many challenges for local firms with growth ...
Bjørkhaug, Hilde, Kvam, Gunn-Turid
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

A neonatal mouse model of central nervous system infections caused by Coxsackievirus B5

open access: yesEmerging Microbes and Infections, 2018
As one of the key members of the coxsackievirus B group, coxsackievirus B5 (CV-B5) can cause many central nervous system diseases, such as viral encephalitis, aseptic meningitis, and acute flaccid paralysis.
Qunying Mao   +11 more
doaj   +1 more source

Drivers of consumer’s adoption of innovative food [PDF]

open access: yes
Over the last years, food safety, health and environmental issues are a few among many other reasons that force consumers to adopt new innovative food products – organic, private label, genetically modified and functional – as part of their consumption ...
Loizou, Efstratios   +2 more
core   +1 more source

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