Immune System Development—Pro Tips for Paediatricians
ABSTRACT There are many misconceptions about the immune system in children, its impact on infectious disease susceptibility and its role in the rapidly increasing rates of immune mediated diseases in industrialized societies. In this mini review, I will discuss common believes and the data supporting or countering such believes, with a focus on ...
Petter Brodin
wiley +1 more source
Concurrent validity and agreement of Bayley‐4, AIMS, and HINE assessments in 1‐year‐old children
In this cross‐sectional study of children around 1‐year‐old, the Bayley‐4 showed concurrent validity and moderate to substantial agreement with the AIMS and the HINE in both clinical and home settings. Abstract Aim To examine concurrent validity between the Bayley Scales of Infant and Toddler Development, Fourth Edition (Bayley‐4) gross motor subtest ...
Weiyang Deng +14 more
wiley +1 more source
Characteristics of children with food protein-induced enterocolitis and allergic proctocolitis
Background: The aim of this study was to determine and compare the clinical and laboratory features of food protein-induced enterocolitis syndrome (FPIES) and food protein-induced allergic proctocolitis (FPIAP), and to provide information about the short-
Buyuktiryaki, Betul +7 more
core +1 more source
Food Protein-Induced Enterocolitis Syndrome Causing Hypovolemic Shock and Methemoglobinemia
A 5-week-old previously healthy male presented with vomiting and diarrhea leading to hypovolemic shock and profound metabolic acidosis. He was subsequently found to have severe methemoglobinemia.
Stefan W. Malin +3 more
doaj +1 more source
Experience in food protein-induced enterocolitis syndrome in a paediatric allergy clinic
Introduction: Food protein-induced enterocolitis syndrome (FPIES) is a gastrointestinal syndrome due to a non-IgE mediated food hypersensitivity. The most common triggers are cow's milk and soy. Fish is one of the most frequently reported causes in Spain.
Rasha Isabel Pérez Ajami +4 more
doaj +1 more source
Translating gut microbiome research into therapies for type 1 diabetes
Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok +2 more
wiley +1 more source
Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda +5 more
wiley +1 more source
Maturation‐Dependent Constraints in the Ability of Human Monocytes to Initiate Trained Immunity
In premature infants, innate immune memory may serve as an important compensatory mechanism for the underdeveloped adaptive immune system. However, monocytes derived from prematurely born individuals display abnormal metabolic and insufficient transcriptomic responses to β‐glucan‐induced training.
Michael Eigenschink +10 more
wiley +1 more source
Immune effector cell‐mediated enterocolitis is an emerging complication of CAR‐T therapy. This review summarizes its epidemiology, pathophysiology, diagnosis, endoscopic and histopathologic features, and evidence‐based management, emphasizing early recognition, multidisciplinary intervention, and step‐up therapy.
John A. Damianos +4 more
wiley +1 more source
Buckwheat Protein-Induced Enterocolitis Syndrome: A Series of Clinical Cases
Introduction. Case reports of Food Protein-Induced Enterocolitis Syndrome (FPIES) associated with buckwheat consumption are quite rare. However, over the course of 3 years at the Federal State Autonomous Institution “National Medical Research Center for ...
I. G. Gordeeva +4 more
doaj +1 more source

