Results 71 to 80 of about 2,501,321 (298)

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

The influence of social media on the dietary behaviors of young Australian adults: A mixed methods exploration

open access: yesMental Health Science
The aims of this study were to (1) determine the impact of social media use on the dietary behaviors of young Australian adults, (2) explore the relationship between social media use and wellbeing, and (3) determine how social media influences dietary ...
Kiera Goerke   +3 more
doaj   +1 more source

Effect of online food delivery service use on dietary choices among older adults [PDF]

open access: yesSHS Web of Conferences
The purpose of this paper is to explore the relationship of the use of online food delivery (OFD) services and the wait time when using OFD services with the diet of older adults.
Liu Chih-Chi, Li Ying-Ju, Lin Hung-Chou
doaj   +1 more source

A win-win for legume mixtures [PDF]

open access: yes, 2011
The inter-relationship between food production and biodiversity is now well established. The ecosystem services provided by the organisms within the environment include, for example, nutrient cycling, pest regulation and pollination, to name but a few ...
Brown, Rob   +5 more
core  

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Recent trends, risk factors, and disparities in low birth weight in California, 2005–2014: a retrospective study

open access: yesMaternal Health, Neonatology and Perinatology, 2018
Background Low birth weight (LBW) is a leading risk factor for infant morbidity and mortality in the United States. There are large disparities in the prevalence of LBW by race and ethnicity, especially between African American and White women.
Anura W. G. Ratnasiri   +6 more
doaj   +1 more source

Archetypes of land transformations and trajectories of ecosystem services in mountains. [ID660] [PDF]

open access: yes, 2019
Based on a synthesis of 51 cases of temporal changes in land use and ecosystem services within mountain landscapes, we analyze how changes in land-use intensity influence the supply of ten key services and we describe six typical archetypes. Our analysis
Locatelli, Bruno
core  

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang   +10 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

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