Results 181 to 190 of about 4,522,117 (368)

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

Préférences des consommateurs et filière de l’attiéké en Côte d’Ivoire

open access: yesRevue Internationale des Études du Développement, 2019
Attiéké is a socio-economically important agro-food product in Côte d’Ivoire. The threat of the disappearance of the original product and its replacement by an industrial version and by garba, has led the country to start the Protected Geographical ...
Trazié Bertrand Athanase Youan Bi
doaj  

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Multiscale risk spillovers and external driving factors: Evidence from the global futures and spot markets of staple foods [PDF]

open access: yesarXiv
Stable and efficient food markets are crucial for global food security, yet international staple food markets are increasingly exposed to complex risks, including intensified risk contagion and escalating external uncertainties. This paper systematically investigates risk spillovers in global staple food markets and explores the key determinants of ...
arxiv  

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

open access: yesFEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli   +15 more
wiley   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

open access: yesFEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui   +5 more
wiley   +1 more source

Editorial: Agriculture and food supply challenges in a changing climate

open access: yesFrontiers in Climate, 2023
Ka Ming Fung   +4 more
doaj   +1 more source

GROWTH AND REPRODUCTION UPON SIMPLIFIED FOOD SUPPLY

open access: hybrid, 1922
H. C. Sherman, Josephine Crocker
openalex   +1 more source

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