Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Infrastructure support for short food supply chains: the current state of play in England and towards a research agenda. [PDF]
Agric Food EconMaye D +4 more
europepmc +1 more source
The Impact of Digitalization on Sustainable Food Supply Chain Management
Ksenija Leković +5 more
openalex +2 more sources
IMPROVING VERTICAL COORDINATION OF AGRICULTURAL INDUSTRIES THROUGH SUPPLY CHAIN MANAGEMENT [PDF]
Supply chain management is an important topic related to improving efficiency, vertical coordination, overall performance and competitiveness in food industries.
Ricks, Donald J. +2 more
core +1 more source
Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian +9 more
wiley +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Analyzing multidrug resistance patterns across the food supply chain using association rule mining. [PDF]
Prev Vet MedGlass JC +5 more
europepmc +1 more source
AIDS and food security: essays [PDF]
AIDS (Disease), Food security., HIV/AIDS Africa., Africa, Sub-Saharan., Epidemics., Food security Developing countries., Food supply., Malnutrition Prevention., Agriculture., Nutrition policies. ,
Gillespie, Stuart +3 more
core
Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley +1 more source