Results 11 to 20 of about 7,444,069 (295)

Omega-3 fatty acids on the forced-swimming test

open access: yesJournal of Psychiatric Research, 2008
Based on the findings of epidemiological data and recent clinical trials, omega-3 fatty acids seem to have a preventive and therapeutic effect on depression.We examined the effect of omega-3 fatty acids on the forced-swimming test (FST) in two groups of Sprague-Dawley rats after a six-week treatment with two different diets.
Huang, S Y   +4 more
openaire   +4 more sources

A Test–Retest Paradigm of the Forced Swimming Test in Female Mice Is Not Valid for Predicting Antidepressant-Like Activity: Participation of Acetylcholine and Sigma-1 Receptors

open access: yesJournal of Pharmacological Sciences, 2013
The forced swimming test (FST) in mice is widely used to predict the antidepressant activity of a drug, but information describing the immobility of female mice is limited.
Jing Su   +3 more
doaj   +2 more sources

Acute reversible inactivation of the bed nucleus of stria terminalis induces antidepressant-like effect in the rat forced swimming test [PDF]

open access: yesBehavioral and Brain Functions, 2010
Background The bed nucleus of stria terminalis (BNST) is a limbic forebrain structure involved in hypothalamo-pituitary-adrenal axis regulation and stress adaptation.
Joca Sâmia RL   +4 more
doaj   +2 more sources

The Mouse Forced Swim Test [PDF]

open access: yesJournal of Visualized Experiments, 2011
The forced swim test is a rodent behavioral test used for evaluation of antidepressant drugs, antidepressant efficacy of new compounds, and experimental manipulations that are aimed at rendering or preventing depressive-like states. Mice are placed in an inescapable transparent tank that is filled with water and their escape related mobility behavior ...
Adem, Can   +5 more
openaire   +2 more sources

Factors influencing behavior in the forced swim test [PDF]

open access: yesPhysiology & Behavior, 2013
The forced swim test (FST) is a behavioral test in rodents which was developed in 1978 by Porsolt and colleagues as a model for predicting the clinical efficacy of antidepressant drugs. A modified version of the FST added the classification of active behaviors into swimming and climbing, in order to facilitate the differentiation between serotonergic ...
Olena V, Bogdanova   +3 more
openaire   +2 more sources

Forced swim test behavior in postpartum rats [PDF]

open access: yesPharmacology Biochemistry and Behavior, 2010
This study was undertaken to determine whether depression-like behavior can be observed in gonadally intact females that have experienced normal pregnancy. When tested on the forced swim test (FST) on postpartum days 1-7, previously pregnant rats spent slightly more time immobile, significantly less time swimming and diving, and defecated more than ...
CRAFT, R. M   +4 more
openaire   +3 more sources

Evaluation of Depressive and Anxious Behavior with the Use of Propranolol in Melanoma-Bearing Mice [PDF]

open access: yesBrazilian Archives of Biology and Technology, 2021
HIGHLIGHTS: Tumor progression and anxiety and depression behaviors under evaluation during propranolol use in murine melanoma. Evaluation of anxiety and depression through forced swimming behavior tests, elevated plus maze, open field and marble ...
Juliana Berton   +4 more
doaj   +1 more source

The effect of montelukast on depression behavior in rat forced swimming test

open access: yesPsychiatry and Behavioral Sciences, 2017
Objective: Montelukast (brand name: Singulair), which is used for treatment of chronic asthma, is a leukotriene receptor antagonist. The psychiatric side effects of montelukast use in asthma patients are controversial. The aim of this study is to examine
Ersoz Gonca
doaj   +1 more source

Effect of zinc oxide nanoparticles on anxiety-related behaviors in male rats

open access: yesSVU-International Journal of Veterinary Sciences, 2020
The objective of this study was to investigate the influences of zinc oxide nanoparticles (ZONPs) on the anxiety-related behaviors of male albino rats. Because of the sexual differences found in the anxiety related disorders, thirty-six male albino rats ...
Ahmed Mohammed   +4 more
doaj   +1 more source

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