Results 41 to 50 of about 7,444,069 (295)

Perbandingan uji efektifitas antidepresan impramin HCL antara metode forced swimming test dan alat waterwhell pada mencit betina [PDF]

open access: yes, 2003
Penelitian ini dilakukan untuk membandingkan efektivitas antidepresan Imipramin HCI antara metode Forced Swimming Test dan Alat Waterwheel dengan dosis 15 mg/kg BB sebanyak 0,3 ml/20 gBB.
Sanjaya, Siska
core   +1 more source

Effects of polysaccharides from Cordyceps sinensis mycelium on physical fatigue in mice

open access: yesBangladesh Journal of Pharmacology, 2012
This study was designed to determine the effects of polysaccharides from Cordyceps sinensis mycelium (CSP) on physical fatigue in mice. The mice were randomly divided into four groups (n = 16 in each group), i.e. control group, low-dose CSP treated group,
Feng Yan, Yan Zhang, Beibei Wang
doaj   +1 more source

The Forced Swim Test as a Model of Depressive-like Behavior [PDF]

open access: yesJournal of Visualized Experiments, 2015
The goal of the present protocol is to describe the forced swim test (FST), which is one of the most commonly used assays for the study of depressive-like behavior in rodents. The FST is based on the assumption that when placing an animal in a container filled with water, it will first make efforts to escape but eventually will exhibit immobility that ...
Roni, Yankelevitch-Yahav   +3 more
openaire   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Investigation of antidepressant -like effect of pari-flo product on forced swiming test in balb-c mice

open access: yesMedicine Science, 2019
Pari-flo is a commercial preparation in the form of a solution containing standardized Passiflora incarnata plant extract. We hypothesized that Pari-flo may have antidepressant potential with its content.
Ismet Yilmaz, Ahmet Berk
doaj   +1 more source

X-Irradiation at 0.5 Gy after the forced swim test reduces forced swimming-induced immobility in mice [PDF]

open access: yesJournal of Radiation Research, 2020
Abstract The forced swim test (FST) is a screening model for antidepressant activity; it causes immobility and induces oxidative stress. We previously reported that radon inhalation has antidepressant-like effects in mice potentially through the activation of antioxidative functions upon radon inhalation.
Kataoka, Takahiro   +9 more
openaire   +3 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Perbandingan efektivitas antidepresan imipramin HCI antara metode forced swimming test dan metode waterwhell pada mencit jantan [PDF]

open access: yes, 2003
Depresi merupakan bentuk gangguan suasana hati yang ditandai dengan adanya karakteristik suasana hati yang berlebihan dengan gangguan fisiologis, kognitif dan psikomotor. Obat yang digunakan sebagai anti depresi adalah Irniprarnin HCI.
., Diana
core   +1 more source

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