Results 91 to 100 of about 56,919 (302)

DNA binding specificity of all four Saccharomyces cerevisiae forkhead transcription factors. [PDF]

Nucleic Acids Res, 2023
Cooper BH, Dantas Machado AC, Gan Y, Aparicio OM, Rohs R.   +4 more
europepmc   +1 more source

Exosomes in Intervertebral Disc Regeneration: Roles, Opportunities, and Challenges

Advanced NanoBiomed Research, EarlyView.
Factors of Intervertebral Disc Degeneration Extracellular Matrix (ECM) Exosomes and Intervertebral Disc Degeneration (IVDD) Exosome‐Mediated Therapy for IVDD of Different Cell Sources Application of Engineered Exosomes in IVDD Clinical Application of Exosomes in IVDD Treatment Conclusion and Future Perspectives. Intervertebral disc degeneration (IVDD),
Xianglong Zhou, Tianyi Xia, Jiheng Xiao, Jianhui Xiang, Hanhong Fang, Haoran Zhou, Yiqiang Hu, Liming Xiong   +7 more
wiley   +1 more source

ER stress and cancer: The FOXO forkhead transcription factor link

Molecular and Cellular Endocrinology, 2018
The endoplasmic reticulum (ER) is a cellular organelle with central roles in maintaining proteostasis due to its involvement in protein synthesis, folding, quality control, distribution and degradation. The accumulation of misfolded proteins in the ER lumen causes 'ER stress' and threatens overall cellular proteostasis. To restore ER homeostasis, cells
Glowi Alasiri, Lavender Yuen-Nam Fan, Stefania Zona, Isabella Galeno Goldsbrough, Hui-Ling Ke, Holger Werner Auner, Eric Wing-Fai Lam   +6 more
openaire   +5 more sources

Role of the Forkhead box family protein FOXF2 in the progression of solid tumor: systematic review

Journal of Cancer Research and Clinical Oncology
Background FOXF2 was reported to involve in a variety of biological behaviors that include the development of the central nervous system, tissue homeostasis, epithelia-mesenchymal interactions, regulation of embryonic development, and organogenesis ...
Yuzhen Zheng, Liusheng Wu, Zhenyu Hu, Hongying Liao, Xiaoqiang Li   +4 more
doaj   +1 more source

Hepatic gluconeogenesis and regulatory mechanisms in lactating ruminants: A literature review

Animal Research and One Health, EarlyView.
phosphoenolpyruvate carboxy kinase, FBP1, and glucose‐6‐phosphatase are key rate‐limiting enzymes that determine the efficiency of gluconeogenesis. The main substrate for gluconeogenesis in the liver of ruminants is propionate, which provides more than 60% of the carbon source for gluconeogenesis.
Guoyan Wang, Yuanyuan Zhu, Dingping Feng, Junhu Yao, Yangchun Cao, Lu Deng   +5 more
wiley   +1 more source

Inferring yeast cell cycle regulators and interactions using transcription factor activities

BMC Genomics, 2005
Background Since transcription factors are often regulated at the post-transcriptional level, their activities, rather than expression levels may provide valuable information for investigating functions and their interactions.
Galbraith Simon J, Brynildsen Mark P, Suen Jason, Yang Young-Lyeol, Liao James C   +4 more
doaj   +1 more source

Lipid metabolism reprograming by SREBP1‐PCSK9 targeting sensitizes pancreatic cancer to immunochemotherapy

Cancer Communications, EarlyView.
Abstract Background Pancreatic cancer's aberrant lipid metabolism fuels cell growth, invasion, and metastasis, yet its impact on immune surveillance and immunotherapy is unclear. This study investigated how sterol regulatory element‐binding transcription factor 1 (SREBP1)‐driven lipid metabolism affects the tumor microenvironment (TME) in pancreatic ...
Mengyi Lao, Xiaozhen Zhang, Zejun Li, Kang Sun, Hanshen Yang, Sicheng Wang, Lihong He, Yan Chen, Hanjia Zhang, Jiatao Shi, Daqian Xu, Tingbo Liang, Xueli Bai   +12 more
wiley   +1 more source

Forkhead transcription factors in the regulation of VEGF in breast cancer

, 2011
High levels of the major angiogenic factor VEGF, have been reported in a number of cancer cell lines and in clinical specimens derived from breast. The forkhead transcription factors important for the regulation of many different physiological processes have been implicated in VEGF regulation in breast cancer. In this study, we have shown the interplay
Karadedou, Christina Theano, Karadedou, Christina Theano   +1 more
openaire   +4 more sources

The putative forkhead transcription factor FhpA is necessary for development, aflatoxin production, and stress response in Aspergillus flavus.

PLoS ONE
Forkhead transcription factors regulate several important biological processes in many eukaryotic species including fungi. Bioinformatic analysis of the Aspergillus flavus genome revealed four putative forkhead transcription factor genes.
Jessica M Lohmar, Stephanie R Gross, Carol H Carter-Wientjes, Brian M Mack, Qijian Wei, Matthew D Lebar, Jeffrey W Cary   +6 more
doaj   +1 more source

Mechanism of forkhead transcription factors binding to a novel palindromic DNA site. [PDF]

Nucleic Acids Res, 2021
Li J, Dai S, Chen X, Liang X, Qu L, Jiang L, Guo M, Zhou Z, Wei H, Zhang H, Chen Z, Chen L, Chen Y.   +12 more
europepmc   +1 more source