Results 81 to 90 of about 7,923,952 (292)

Transcriptional Regulation of Neuronal Genes and Its Effect on Neural Functions: NAD-Dependent Histone Deacetylase SIRT1 (Sir2α)

open access: yesJournal of Pharmacological Sciences, 2005
Sir2 (silent information regulator 2) is an NAD-dependent deacetylase that is broadly conserved from bacteria to humans. It catalyzes a unique deacetylation reaction using NAD, and specific inhibitors and activators of its activity have been discovered ...
Shin Hisahara   +3 more
doaj   +1 more source

Forkhead transcription factors in brain development : 'Fox hunting in midbrain dopaminergic neurons' [PDF]

open access: yes, 2005
The forkhead family is a quickly expanding family of transcription factors that are important for embryonic development. They control fundamental developmental processes by mediating the transcriptional activation of downstream effector genes.
Wijchers, Patrick Jurriaan Evert Cornelis
core   +1 more source

Forkhead transcription factors establish origin timing and long-range clustering in S. cerevisiae [PDF]

open access: yes, 2012
The replication of eukaryotic chromosomes is organized temporally and spatially within the nucleus through epigenetic regulation of replication origin function.
Viggiani, C. J.   +15 more
core   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

open access: yesAdvanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao   +10 more
wiley   +1 more source

Regulation of cell survival and proliferation by the FOXO (Forkhead box, class 0) subfamily of forkhead transcription factors

open access: yes, 2003
Recently, the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors has been identified as direct targets of phosphoinositide 3-kinase-mediated signal transduction.
Birkenkamp, KU, Coffer, PJ
core   +1 more source

The relationship between the variants in the 5′-untranslated regions of equine chorionic gonadotropin genes and serum equine chorionic gonadotropin levels [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2017
Objective An experiment was conducted to study the association between the single nucleotide polymorphisms (SNPs) in 5′-untranslated regions (5′-UTR) of equine chorionic gonadotropin (eCG) genes and the serum eCG levels.
ShuQin Liu   +7 more
doaj   +1 more source

Functional interactions between the Forkhead transcription factor FOXK1 and the MADS-box protein SRF [PDF]

open access: yes, 2007
The combinatorial control of gene expression by the association of members of different families of transcription factors is a common theme in eukaryotic transcriptional control.
Ji, Zongling   +7 more
core   +1 more source

The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John   +4 more
wiley   +1 more source

The forkhead transcription factor Foxc2 stimulates osteoblast differentiation

open access: yesBone, 2009
The forkhead box C2 (Foxc2) protein is a member of the family of winged helix/forkhead transcription factors. Foxc2-deficient mice display defective formation of the aortic arches, multiple craniofacial bones, and vertebral columns. To investigate the role of Foxc2 in osteoblast differentiation, DNA containing Foxc2 was transfected into the developing ...
Lim, SK   +6 more
openaire   +4 more sources

Histological Characterization and Comparative Transcriptomic Analysis of Gonads During Early Sex Differentiation in the Northern Snakehead (Channa argus)

open access: yesAnimal Research and One Health, EarlyView.
This study delineates the early sex differentiation timeline in the northern snakehead (Channa argus). These findings provide a foundation for future sex‐control breeding in this economically important species. ABSTRACT The northern snakehead (Channa argus) is an economically important aquaculture species in China.
Chaonan Sun   +6 more
wiley   +1 more source

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