Results 101 to 110 of about 94,681 (279)

Forkhead box transcription factor regulation and lipid accumulation by hepatitis C virus [PDF]

, 2014
We have previously shown that hepatitis C virus (HCV) infection modulates the expression of forkhead box transcription factors, including FoxO1 and FoxA2, which play key roles in gluconeogenesis and β-oxidation of fatty acid, respectively. The aim of the
Bose, Sandip K, Davidson, Nicholas O, Kim, Hangeun, Meyer, Keith, Ray, Ranjit, Wolins, Nathan   +5 more
core   +2 more sources

Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby

Developmental Dynamics, EarlyView.
Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe, Yu Chen, Geoff Shaw, Marilyn B. Renfree   +3 more
wiley   +1 more source

Potential of the  FOX gene family and LncRNAs as biomarkers in differentiated thyroid cancer treated with I-131

Türk Biyokimya Dergisi
Forkhead box (FOX) transcription factors and long non-coding RNAs (lncRNAs) localize within tumor cell nuclei in various cancers, suggesting their involvement in transcriptional regulation. This study aimed to investigate expression changes of FOX family
Agbektas Tugba, Tas Ayca, Sariakcali Baris, Hasbek Zekiye, Silig Yavuz   +4 more
doaj   +1 more source

Recruitment of Fkh1 to replication origins requires precisely positioned Fkh1/2 binding sites and concurrent assembly of the pre-replicative complex.

PLoS Genetics, 2017
In budding yeast, activation of many DNA replication origins is regulated by their chromatin environment, whereas others fire in early S phase regardless of their chromosomal location. Several location-independent origins contain at least two divergently
Allan Reinapae, Kristiina Jalakas, Nikita Avvakumov, Marko Lõoke, Kersti Kristjuhan, Arnold Kristjuhan   +5 more
doaj   +1 more source

Phylogenetic analysis of forkhead transcription factors in the Panarthropoda. [PDF]

Dev Genes Evol, 2022
Schomburg C, Janssen R, Prpic NM.
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Role of the Forkhead box family protein FOXF2 in the progression of solid tumor: systematic review

Journal of Cancer Research and Clinical Oncology
Background FOXF2 was reported to involve in a variety of biological behaviors that include the development of the central nervous system, tissue homeostasis, epithelia-mesenchymal interactions, regulation of embryonic development, and organogenesis ...
Yuzhen Zheng, Liusheng Wu, Zhenyu Hu, Hongying Liao, Xiaoqiang Li   +4 more
doaj   +1 more source

Role of forkhead transcription factors in endocrine sensitive and resistant breast cancer cell lines

, 2010
Breast cancer is a major concern worldwide as it accounts for one of the highest causes of death. Oestrogen which is widely known for its growth-promoting function in mammary gland has been linked to breast cancer pathogenesis.
Sivanandan, Kavitta, Sivanandan, Kavitta
core   +1 more source

Role of Forkhead Transcription Factors in Myocardial Ischemic Reperfusion Injury in Diabetes [PDF]

, 2013
Diabetes, characterized by hyperglycemia resulting from either insulin deficiency or insulin resistance, is a chronic metabolic disorder. Hearts of subjects with diabetes are more sensitive to myocardial ischemia/reperfusion injury but the underlying ...
Irwin, MG, LI, H, Li, Y, Tao, M, Xia, Z, Zhang, L   +5 more
core   +1 more source

Tumor‐Intrinsic Forkhead Box A2 Regulates the Lymph Node Metastasis of Papillary Thyroid Carcinoma by Regulating T‐Cell Apoptosis

iLABMED, EarlyView.
We identified FOXA2 as a key regulator of lymph node metastasis in thyroid cancer, which controls cancer cell aggressiveness. FOXA2 knockdown promotes metastasis by enhancing tumor cell migration and, importantly, by inducing T‐cell apoptosis through a CCL2/LCN2‐mediated pathway. Created with BioGDP.com.
Ping Yang, Xueying Zhang, Wen Deng, Fangning Gao, Shujia Peng, Guoqiang Bao, Lijuan Yuan   +6 more
wiley   +1 more source