Results 261 to 270 of about 94,681 (279)

Hierarchical interactions of homeodomain and forkhead transcription factors in regulating odontogenic gene expression. [PDF]

J Biol Chem, 2011
Venugopalan SR, Li X, Amen MA, Florez S, Gutierrez D, Cao H, Wang J, Amendt BA.   +7 more
europepmc   +1 more source

FAM20C Modulates Neuronal Differentiation in Hypoxic–Ischemic Brain Damage via KAP1 Phosphorylation and LINE1 RNA m6A‐Dependent H3K9me3 Regulation

Cell Proliferation, Volume 59, Issue 1, January 2026.
FAM20C regulates the composition of the YTHDC1‐NCL‐KAP1‐LINE1 RNAs complex, thereby affecting neuronal differentiation in hypoxic–ischemic brain damage (HIBD). ABSTRACT Neurodevelopmental impairment due to hypoxic–ischemic brain damage (HIBD) lacks effective biomarkers and therapeutic targets.
Chen‐xi Feng, Mei Wang, Gen Li, Si‐jia Chu, Di Wu, Xiao‐han Hu, Li‐xiao Xu, Mei Li, Xing Feng   +8 more
wiley   +1 more source

Osteochondrosis in horses: An overview of genetic and other factors

Equine Veterinary Journal, Volume 58, Issue 1, Page 6-19, January 2026.
Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez, Pablo J. Marín‐García, M. Lola Llobat   +2 more
wiley   +1 more source

FOXP4 Variants Are Associated With Plateau Iris and Angle Closure Glaucoma. [PDF]

Invest Ophthalmol Vis Sci
Presley W, Wang SQ, Guan B, Jeong SH, Bender C, Ward E, Johnson K, Blevins B, Michaels N, Shah M, Moroi SE, Hufnagel RB, Richards JE, Prasov L.   +13 more
europepmc   +1 more source

TDP‐43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models

The FEBS Journal, Volume 293, Issue 2, Page 348-384, January 2026.
The manuscript explores structural and functional features of TDP‐43 and its worm homologue, TDP‐1, highlighting conserved and divergent structural and functional features. Using genetically engineered C. elegans models, key pathological features of TDP‐43 proteinopathies—including aggregation, neurodegeneration, and motor deficits—are recapitulated ...
Ghulam Jeelani Pir, Joerg Buddenkotte, Majid Ali Alam, Ahmed Own, Randall J. Eck, Brian C. Kraemer, Eckhard Mandelkow, Martin Steinhoff   +7 more
wiley   +1 more source

Sex in Immune Cells and Parasitic Diseases — A Complex Relationship

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker, Charlotte Sophie Hansen, Hanna Lotter   +2 more
wiley   +1 more source

FoxO3a‐Mediated Modulation of PD‐L1 Expression and Inhibition by Dihydroartemisinin in Triple‐Negative Breast Cancer

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Tumour immunotherapy targeting PD‐1/PD‐L1 shows promise, but the regulatory mechanisms of PD‐L1 and its small‐molecule modulators remain unclear. This study investigated FoxO3a‐mediated PD‐L1 regulation and the PD‐L1‐inhibitory role of dihydroartemisinin (DA) in triple‐negative breast cancer (TNBC).
Xingan Xing, Zhiwei Zhou, Mohd Farhan, Xia Zhao, Shuai Li, Bingxi Lei, Jiankang Fang, Wenshu Zhou, Wenhua Zheng   +8 more
wiley   +1 more source

Massive hepatic necrosis-associated acute liver failure. [PDF]

eGastroenterology
Lin T, Tong C, Liebe R, Weng H.
europepmc   +1 more source

Exploring Bilirubin’s Impact on Autophagy and Apoptosis in Diabetic Kidney Disease

BioMed Research International, Volume 2026, Issue 1, 2026.
Background Diabetic kidney disease (DKD) affects nearly half of patients with type 1 or type 2 diabetes and is a leading cause of end‐stage renal disease (ESRD). Maladaptive autophagy and increased apoptosis have been observed in diabetic kidneys. Bilirubin, a natural antioxidant, may exert protective effects against DKD progression; however, the ...
Mohammad Hasan Maleki, Zahra Dashti, Alireza Monsef, Morvarid Siri, Hamed Jamali, Raika Naiebi, Fatemeh Omidi, Amirreza Dehghanian, Sayed Mohammad Shafiee, Weiqiang Zhang   +9 more
wiley   +1 more source

Expression of Glucocorticoid Receptor and FOXO1/phospho-FOXO1 in Bladder Cancer as Independent Prognosticators. [PDF]

Cancer Genomics Proteomics
Ide H, Najafi MAE, Matsukawa T, Tatenuma T, Oya M, Miyamoto H.   +5 more
europepmc   +1 more source