Results 261 to 270 of about 56,919 (302)

Transcriptomic time course of skeletal muscle disuse and rehabilitation in middle‐aged adults

open access: yesPhysiological Reports, Volume 13, Issue 15, August 2025.
Abstract Disuse drives rapid muscle atrophy and metabolic dysfunction. This study aimed to characterize phenotypic and transcriptomic skeletal muscle changes in middle‐aged individuals during disuse and rehabilitation. Eleven healthy middle‐aged adults (6 males, 5 females; age; 57 ± 5 years) underwent 7 days of unilateral lower limb suspension (ULLS ...
Zachary D. Von Ruff   +9 more
wiley   +1 more source

Forkhead Transcription Factors in Health and Disease

Trends in Genetics, 2021
Forkhead box (FOX) proteins belong to an evolutionarily conserved family of transcription factors that has evolved by gene/genome duplication. FOX family members have undergone sequence and regulatory diversification. However, they have retained some degree of functional redundancy, in addition to playing specific roles, both during development and in ...
Reiner A. Veitia   +3 more
openaire   +3 more sources

Regulation of mitochondrial function by forkhead transcription factors

Biochimie, 2022
Mitochondria play a central role in several important cellular processes such as energy production, apoptosis, fatty acid catabolism, calcium regulation, and cellular stress response. Multiple nuclear transcription factors have been reported for their role in the regulation of mitochondrial gene expression.
Maria Sona Jerome   +3 more
openaire   +2 more sources

Forkhead transcription factors in immunology

CMLS Cellular and Molecular Life Sciences, 2005
The forkhead (Fox) gene family comprises a diverse group of "winged-helix" transcription factors that play important roles in development, metabolism, cancer and aging. Recently, several forkhead genes have been demonstrated to play critical roles in lymphocyte development and effector function, including Foxp3 in the development of regulatory T cells,
S. L. Peng, H. Jonsson
openaire   +3 more sources

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