Rescue of Angiopoietin‐2 Inhibits Proliferation of Lymphatic Malformation Endothelial Cells
Mechanistic summary of how autocrine ANG2 suppressed LMEC proliferation. Somatic activating SNVs in PIK3CA result in increased PI3K/Akt signaling, Akt‐mediated downregulation of ANG2, and LMEC hyperproliferation. Restoration of autocrine ANG2 in LMECs through overexpression suppressed LMEC proliferation in vitro and lymphangiogenesis in vivo and was ...
Ravi W. Sun +10 more
wiley +1 more source
Efficacy of DMARDs Therapy on the Disease Activity and Gene Expression Levels of FoxO1, FoxO3, Runx1, and Runx3 in Early Rheumatoid Arthritis Patients: A Pre-Post Interventional Study With Healthy Controls. [PDF]
Roghani SA +11 more
europepmc +1 more source
Defective mitochondrial unfolded protein response in cancer acts as a lifeline for tumor growth and survival. [PDF]
Sharma U +10 more
europepmc +1 more source
The role of FoxO3a in the pathogenesis of osteoarthritis and its therapeutic applications. [PDF]
Wu Z +7 more
europepmc +1 more source
Novel fold and wing structure of Forkhead transcription factor facilitate DNA binding. [PDF]
Wang GL +9 more
europepmc +1 more source
Control of hepatic gluconeogenesis through the forkhead transcription factor FKHR
浩照 大徳
openalex
Forkhead box O proteins in chondrocyte aging and diseases. [PDF]
He Y +7 more
europepmc +1 more source

