Results 121 to 130 of about 6,977,566 (297)
Advanced Science, EarlyView.This study uncovers a previously unrecognized copper‐COMMD1‐SOD1 regulatory axis, revealing that pathological copper overload paradoxically suppresses SOD1 activity by promoting COMMD1‐dependent disruption of SOD1 homodimerization. These findings redefine the regulatory role of copper in SOD1 biology and provide novel mechanistic insight into the ...
Yuqing Liu +7 more
wiley +1 more source
Assessment of hydroalcoholic extract of Thymus Vulgaris on neurogenic and inflammatory pain in mice
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2005 Background and Objective: The side effects of anti-nociception chemical drugs caused notice to medical plants. This study was performed to investigate the effects of hydroalcoholic extract of Thymus vulgaris (TV) on neurogenic and inflammatory pain in ...
AA Taherian +7 more
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Antinociceptive effects of intrathecal cimifugin treatment: a preliminary rat study based on formalin test. [PDF]
Anesth Pain Med (Seoul), 2020 Lee HY +6 more
europepmc +1 more source
Advanced Science, EarlyView.Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou +11 more
wiley +1 more source
Journal of Pain Research, 2020 Queensley Eghianruwa,1,2 Omolaja Osoniyi,3 Naomi Maina,1,4 Sabina Wachira,5 Mabel Imbuga4 1Department of Molecular Biology and Biotechnology, Pan African University Institute of Science, Technology and Innovation, JKUAT campus, Juja, Kenya; 2Department ...
Eghianruwa Q +4 more
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Demonstration; Drawbar Test; Waterloo Boy
, 1956 Demonstration at the Tractor Test Lab. This Waterloo Boy's manufacturer was bought later by John Deere. "Waterloo Boy by John Deere on kerosene was the first tractor tested at the University of Nebraska in 1920." The Waterloo Boy tractor is shown on the ...
Nebraska Tractor Test Laboratory
core
Advanced Science, EarlyView.A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li +15 more
wiley +1 more source
Investigation of noradrenergic receptor system in anti-nociception using formalin test in the naked mole rat (Heterocephalus glaber). [PDF]
Heliyon, 2020 Mwobobia RM, Kanui TI, Abelson KSP.
europepmc +1 more source
Advanced Science, EarlyView.ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su +4 more
wiley +1 more source
Journal of Medicinal Plants, 2011 Background: Studies have emphasized the effect of Trigonella foenum-graecum extract on the reduction of pain and inflammation. Objective: In this research we investigated the mechanisms of Trigonella foenum-graecum extract in reducing pain and ...
B Rastegar Moghadam +8 more
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