HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer [PDF]
, 2013 Introduction: Recent data suggest that benefit from trastuzumab and chemotherapy might be related to expression of HER2 and estrogen receptor (ESR1). Therefore, we investigated HER2 and ESR1 mRNA levels in core biopsies of HER2-positive breast carcinomas
A Goldhirsch +62 more
core +1 more source
Refinement of pain evaluation techniques. The formalin test.
Annali dell'Istituto superiore di sanita, 2004 The formalin test is an important means of assessing pain evoked-behaviours induced by moderately intense and long-lasting noxious stimuli, yet the procedures for performing the test have not been standardised, hindering comparisons of data. In rodents, the level of sensitivity to the test and the evoked response have been observed to change depending ...
Capone F, ALOISI, ANNA MARIA
openaire +2 more sources
Understanding the Effects of Conductive Polymer Electrode Coating on Recorded Neural Signals
Advanced Healthcare Materials, EarlyView.Conductive polymer coatings are widely explored to improve the quality of signals recorded with chronically implanted neural electrodes, offering enhanced biocompatibility along with reduced electrode impedance. Combining computational modelling and data from PEDOT:PTS coated and PtIr electrodes in rats, we show that improvements in signal quality with
Karthik Sridhar +4 more
wiley +1 more source
The Additive Antinociceptive Effect of Resveratrol and Ketorolac in the Formalin Test in Mice. [PDF]
Pharmaceuticals (Basel), 2023 Rojas-Aguilar FA +5 more
europepmc +1 more source
Slow in Motion but Smart in Learning and Memory: Behavioral Changes in Adult NR3A Knockout Mice [PDF]
, 2011 The expression of NMDA receptor subunit NR3A is high in the neonatal brain but low in adults. However, its functional role in the adult brain is obscure.
Ling Wei +3 more
core +1 more source
Oncogenic microRNAs characterization in clear cell renal cell carcinoma [PDF]
, 2015 A key challenge for the improvement of clear cell renal cell carcinoma (ccRCC) management could derive from a deeper characterization of the biology of these neoplasms that could greatly improve the diagnosis, prognosis and treatment choice. The aim of
BELLISSIMO, TERESA +8 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar +7 more
wiley +1 more source
Length correction for larval and early-juvenile Atlantic menhaden (Brevoortia tyrannus) after preservation in alcohol [PDF]
, 2005 Body length measurement is an important part of growth, condition, and mortality analyses of larval and juvenile fish. If the measurements are not accurate (i.e., do not reflect real fish length), results of subsequent analyses may be affected ...
Fey, Dariusz P., Hare, Jonathan A.
core
Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior [PDF]
, 2006 The S100 family protein p11 (S100A10, annexin 2 light chain) is involved in the trafficking of the voltage-gated sodium channel Na(V)1.8, TWIK-related acid-sensitive K+ channel (TASK-1), the ligand-gated ion channels acid-sensing ion channel 1a (ASIC1a ...
Baker, MD +8 more
core +1 more source
The Possible Anti-nociceptive Effect of Troxerutin and Neural Interactions Using Formalin and Writhing Tests in Mice [PDF]
, 2023 Farima Jafari-Tirabadi +2 more
openalex +1 more source