Results 101 to 110 of about 806,605 (263)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Les TIC, liens possibles de leur utilisation dans les universités et en formation continue /

open access: yes, 2000
"Conférence d'ouverture dans le cadre du Colloque sur la formation à distance à Rimouski le 10 mai 2000"Bibliogr.: f.
Colloque sur la formation à distance (2000 : Rimouski, Québec)   +1 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Formation à distance, pandémie et pauvreté à Madagascar

open access: yesRevue internationale des technologies en pédagogie universitaire, 2020
Harinosy Ratompomalala   +1 more
doaj   +1 more source

Quelle appréciation de la formation à distance aujourd’hui ? Le point de vue de quelques enseignants en contexte postpandémique

open access: yesMédiations & Médiatisations
La pandémie a été l’occasion, pour beaucoup d’enseignants, de découvrir ou d’approfondir leurs connaissances et compétences en formation à distance (FAD).
Cathia Papi
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Campus numériques : enjeux et perspectives pour la formation ouverte et à distance

open access: yes
Rapport de mission au ministère de l\u27Education nationale, ministère de la Recherche, délégation à l\u27Aménagement du territoire et à l\u27action régionale - Enjeux des nouvelles technologies pour l\u27éducation et la formation.
Averous, Michel
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

À lire : Compétences et formation à distance

open access: yes, 2014
ALBERO Brigitte, SAFOURCADE Sandra, « Compétences et formation à distance : des prescriptions du dispositif aux attitudes des étudiants ». In Distances et médiations des savoirs [En ligne], n° 6, 2014.
Rédaction
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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