Results 51 to 60 of about 40,094 (255)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Real-time and formative evaluation elements in university education in Hungary [PDF]

open access: yesEdukacja Ustawiczna Dorosłych, 2018
Nowadays we all are the witnesses of the rapid changes in technology around us, the changes in students’ learning attitudes and the new demands of the labour market.
Viktória H. BAKONY, Zoltan ILLES
doaj  

Using the Project INTEGRATE Framework in Practice in Central Coast, Australia

open access: yesInternational Journal of Integrated Care, 2019
Introduction: Integrated care implies sustained change in complex systems and progress is not always linear or easy to assess. The Central Coast integrated Care Program (CCICP) was planned as a ten-year place-based system change.
Donna M.Y. Read   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The many functions of evaluation in education

open access: yesEducation Policy Analysis Archives, 2018
This paper focuses upon the many functions that are served by evaluations, and by the process of conducting them. Many forms or types of evaluation have evolved to serve these different functions; and a brief account is given of some of the most common ...
D. C. Phillips
doaj   +1 more source

Formative Evaluation

open access: yes
Formative ...
Charles M. Reigeluth   +2 more
  +5 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Pre-exámenes como una estrategia didáctica en los cursos de Física / Sample test as a teaching strategy in Physics courses

open access: yesActualidades Investigativas en Educación, 2010
Se describe la experiencia del uso de pre-exámenes o exámenes de prueba como una estrategia didáctica para el mejoramiento en el rendimiento y en el desempeño estudiantil en los cursos propios de la carrera de física.
Herbert Morales Ríos
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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