Results 61 to 70 of about 40,094 (255)
Journal of Educational, Cultural and Psychological Studies, 2011 Rethinking Quality Evaluation Models and Practices in Kindergartens. An Explorative Study in the Field of Formative Educational Evaluation This article presents the three-year progress and main results of an educational evaluation study conducted with a
Ira Vannini, Rossella D'Ugo
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Revista Iberoamericana sobre Calidad, Eficacia y Cambio en Educación, 2018 The text presents a case study accomplished by the team of the Studies of the Human Learning Laboratory, of the State of Rio de Janeiro University.
Eloiza da Silva Gomes de Oliveira +5 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A formative evaluation of a pay-for-performance system
SA Journal of Human Resource Management, 2012 Orientation: Pay-for-performance (PFP) systems emerged during the 1980s as performance improvement tools. However, research findings have shown contradictory evidence as to whether these systems motivate employees to improve their performance ...
Lindsey Joseph +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Journal of MultiDisciplinary Evaluation, 2019 Background: Little is known about the status of program evaluation culture and practice in the English Speaking Commonwealth Caribbean (ESCC). This study examined the extent of evaluation culture and practice in four small Caribbean nations: Barbados ...
Nadini Persaud
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
La importancia de la contextualización curricular en la enseñanza de la Historia en México
Panta rei, 2018 The intention of this paper is to analyze the importance of curricular contextualization in the history teaching in Mexican junior high school. This implies the generation of educational experiences that support the development of historical thinking ...
Enrique Bautista-Rojas
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source