Results 101 to 110 of about 612,190 (327)

Evolution of spoon-shaped networks

, 2016
We consider a regular embedded network composed by two curves, one of them closed, in a convex domain $\Omega$. The two curves meet only in one point, forming angle of $120$ degrees. The non-closed curve has a fixed end point on $\partial\Omega$.
Pluda, Alessandra
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Forming limit curves of ultra-thin sheet metal for high-speed Nakajima test [PDF]

, 2022
Ying Zhang, Chen Yu Xie, Zheng Yuan, Xiu Jia Tang, Guoqing Zhang   +4 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

A biaxial test for rheological and formability identification

EPJ Web of Conferences, 2010
Accurate constitutive laws and formability limits of materials are essential for a numerical optimization of sheet forming processes. The main objective of this work is to develop a new experimental device able to give for a unique specimen a good ...
Ragneau E., Léotoing L., Guines D., Zidane I.   +3 more
doaj   +1 more source

Inverse Compton Contribution to the Star-Forming Extragalactic Gamma-Ray Background

, 2012
Fermi has resolved several star-forming galaxies, but the vast majority of the star-forming universe is unresolved and thus contributes to the extragalactic gamma ray background (EGB). Here, we calculate the contribution from star-forming galaxies to the
Abazajian, Abdo, Abdo, Abdo, Abdo, Abramowski, Ackermann, Ahlers, Ando, Ando, Blumenthal, Brian D. Fields, Bringmann, Caraveo, Cirelli, de Cea del Pozo, Faucher-Giguère, Felten, Felten, Fields, Ginzburg, Hayakawa, Hensley, Horiuchi, Hunter, Jones, Kennicutt, Lacki, Lacki, Lacki, Lebrun, Lien, Makiya, Malyshev, McConville, Moskalenko, Moskalenko, Murphy, Nachiketa Chakraborty, Nolan, Padovani, Paglione, Pavlidou, Pavlidou, Persic, Persic, Pohl, Pohl, Porter, Robitaille, Salamon, Sanders, Sreekumar, Stecker, Stecker, Strong, Strong, Strong, Strong, Strong, Thompson, Torres, Voelk, Völk   +63 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Distances to nearby molecular clouds and star forming regions.III. Localizing extinction jumps with a Hipparcos calibration of 2mass photometry [PDF]

, 2010
We want to estimate the distance to molecular clouds in the solar vicinity in a statistically precise way. Clouds are recognized as extinction discontinuities. The extinction is estimated from the $(H-K) \ vs.
Knude, Jens
core   +1 more source

IR observations of MS 1054-03: Star Formation and its Evolution in Rich Galaxy Clusters

, 2007
We study the infrared (IR) properties of galaxies in the cluster MS 1054-03 at z=0.83 by combining MIPS 24 micron data with spectra of more than 400 galaxies and a very deep K-band selected catalog.
Delphine Marcillac, Devriendt J. E. G., Douglas M. Kelly, Gavazzi G., George H. Rieke, Gregory Rudnick, Joannah L. Hinz, Kim‐Vy H. Tran, Kodama T., Lei Bai, Marcia J. Rieke, Metcalfe L., Myra Blaylock, Tanaka M.   +13 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source