Results 91 to 100 of about 487,180 (307)

MOSFIRE Spectroscopy of Quiescent Galaxies at 1.5 < z < 2.5. II - Star Formation Histories and Galaxy Quenching [PDF]

, 2019
We investigate the stellar populations for a sample of 24 quiescent galaxies at 1.5 < z < 2.5 using deep rest-frame optical spectra obtained with Keck MOSFIRE. By fitting templates simultaneously to the spectroscopic and photometric data, and exploring a
Belli, Sirio, Ellis, Richard S., Newman, Andrew B.   +2 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Apparatus Design and Finite Element Modeling for Controlled‐Speed Nakazima Experiments

Engineering Reports
A scaled apparatus was designed for conducting Nakazima stretch‐forming tests with a rotating tool. A 3D finite element model was developed and validated to simulate the modified Nakazima experiments.
Radouane Benmessaoud
doaj   +1 more source

The secondary forming limit diagrams of sheet metals.

TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A, 1985
The forming limit diagrams of proportionally pre-strained metal sheets (secondary FLDs) such as killed steel, copper and aluminium sheets are experimentally determined for combination of uniaxial and equi-biaxial tension as well as the common FLDs for simple loadings.
Manabu GOTOH, Takeshi SATOH, Kozo TANAKA
openaire   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Evaluation of the formability of 90/10 brass produced by different casting processes and investigation of the effect of Forming Limit Diagram determination procedure

Journal of Materials Research and Technology, 2019
The present work investigated the formability of 1.1 mm thick sheets of 90/10 brass (UNS C22000) alloy obtained by two different process routes: continuous casting (CC) and semi-continuous casting (SCC).
Leandro de Almeida, Cláudio Geraldo Schön   +1 more
doaj   +1 more source

The OPTX Project IV: How Reliable is [OIII] as a Measure of AGN Activity?

, 2010
We compare optical and hard X-ray identifications of AGNs using a uniformly selected (above a flux limit of f_2-8 keV = 3.5e-15 erg/cm2/s) and highly optically spectroscopically complete ( > 80% for f_2-8 keV > 1e-14 erg/cm2/s and > 60% below) 2-8 keV ...
A. J. Barger, Alonso-Herrero, Antonucci, Barger, Barger, Bassani, Beckmann, Blanton, Comastri, Cowie, Diamond-Stanic, Ferruit, Hao, Heckman, Heckman, Kakazu, Kewley, L. Trouille, La Franca, La Massa, Laurent-Muehleisen, Meléndez, Moran, Ptak, Reyes, Rigby, Silverman, Steffen, Szokoly, Tremonti, Trouille, Trouille, Ueda, Weedman, Winter, Winter, Yencho, Zakamska   +37 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Bright Ultraviolet Regions and Star Formation Characteristics in Nearby Dwarf Galaxies

, 2009
We compare star formation in the inner and outer disks of 11 dwarf Irregular galaxies (dIm) within 3.6 Mpc. The regions are identified on GALEX near-UV images, and modeled with UV, optical, and near-IR colors to determine masses and ages.
Alongi, Billett, Boissier, Bressan, Bruce G. Elmegreen, Chandar, de Blok, Deidre A. Hunter, Diaz, Dolphin, Drissen, Elmegreen, Elmegreen, Elmegreen, Elmegreen, Fagotto, Fagotto, Fall, Hunter, Hunter, Hunter, Hunter, Hunter, Hunter, Komiyama, Lea Zernow, Lee, Leitherer, Liu, Martin, Martin, Massey, Massey, McQuinn, Meylan, Nicholas W. Melena, Rafelski, Schaye, Thilker, VandenBerg, Whitmore, Yang, Young, Youngblood, Zhang   +44 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source