Results 81 to 90 of about 71,625 (304)

The effect of strain rate and temperature on forming limit diagram for DKP-6112 and AZ31 materials [PDF]

, 2020
Forming limit diagrams (FLDs) are used in sheet metal operations widely for predicting blank fracture and forming characteristics of materials. There are three approaches for building forming limit diagrams which are the experimental, theoretical and ...
Darendeliler, Haluk, Goksen, Seckin
core   +1 more source

Apparatus Design and Finite Element Modeling for Controlled‐Speed Nakazima Experiments

Engineering Reports
A scaled apparatus was designed for conducting Nakazima stretch‐forming tests with a rotating tool. A 3D finite element model was developed and validated to simulate the modified Nakazima experiments.
Radouane Benmessaoud
doaj   +1 more source

The Establishment of Surface Roughness as Failure Criterion of Al–Li Alloy Stretch-Forming Process

Metals, 2016
Taking Al–Li–S4–T8 Al–Li alloy as the study object, based on the stretching and deforming characteristics of sheet metals, this paper proposes a new approach of critical orange peel state characterizations on the basis of the precise measurement of ...
Jing-Wen Feng, Li-Hua Zhan, Ying-Ge Yang
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Modeling of the Forming Limit Diagram for Ferritic Stainless Steel Sheets Incorporating Surface Roughness Development Effect

, 2012
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core  

Evaluation of the formability of 90/10 brass produced by different casting processes and investigation of the effect of Forming Limit Diagram determination procedure

Journal of Materials Research and Technology, 2019
The present work investigated the formability of 1.1 mm thick sheets of 90/10 brass (UNS C22000) alloy obtained by two different process routes: continuous casting (CC) and semi-continuous casting (SCC).
Leandro de Almeida, Cláudio Geraldo Schön   +1 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Forming Limit Stress Diagram Prediction of Pure Titanium Sheet Based on GTN Model

, 2019
In this paper, the initial values of damage parameters in the Gurson–Tvergaard–Needleman (GTN) model are determined by a microscopic test combined with empirical formulas, and the final accurate values are determined by finite element reverse
Mei Zhan, Fuxiao Chen, Junqing Guo, Luge Bai, Yanyang Li, Zhuo Song, Tao Huang, Kun Wang   +7 more
core   +1 more source

Detection of delamination of steel-polymer sandwich composites using acoustic emission and development of a forming limit diagram considering delamination. [PDF]

Heliyon, 2023
Yang J, Han S, Yu WR.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source