Background: The extrafine single inhaler triple therapy (efSITT) containing beclomethasone dipropionate/formoterol fumarate/glycopyrronium 87/5/9 μg has proved to be efficacious in patients with chronic obstructive pulmonary disease (COPD) in randomized ...
Paschalis Steiropoulos +9 more
doaj +1 more source
Prediction of disease progression, treatment response and dropout in chronic obstructive pulmonary disease (COPD). [PDF]
Drug development in chronic obstructive pulmonary disease (COPD) has been characterised by unacceptably high failure rates. In addition to the poor sensitivity in forced expiratory volume in one second (FEV1), numerous causes are known to contribute to ...
Danhof, M +6 more
core +1 more source
The European List of Key Medicines for Medical Education: A Modified Delphi Study
Rational prescribing is essential for the quality of health care. However, many final‐year medical students and junior doctors lack prescribing competence to perform this task. The availability of a list of medicines that a junior doctor working in Europe should be able to independently prescribe safely and effectively without supervision could support
Erik M. Donker +198 more
wiley +1 more source
Effect of fixed-dose subcutaneous reslizumab on asthma exacerbations in patients with severe uncontrolled asthma and corticosteroid sparing in patients with oral corticosteroid-dependent asthma : results from two phase 3, randomised, double-blind, placebo-controlled trials [PDF]
BACKGROUND: Reslizumab 3 mg/kg administered intravenously is approved for the treatment of severe eosinophilic asthma. We assessed the safety and efficacy of subcutaneous reslizumab 110 mg in two trials in patients with uncontrolled severe asthma and ...
Adir, Yochai +13 more
core +1 more source
A perspective current and past modes of inhalation therapy
Abstract Inhalation is the preferred route of delivery for anti‐asthma and chronic obstructive pulmonary disease (COPD) drugs. The use of this route has demonstrated efficacy in these and other conditions, it offers rapid onset of action, and is associated with minimal systemic exposure, thereby reducing the risk of adverse effects.
José Canto Mangana +6 more
wiley +1 more source
BDP/FF NEXThaler to Improve Asthma Control Status in the Real World: The NEWTON Study
Fulvio Braido,1,2 Enrico Arnaboldi,1,2 Sara Barile,3 Luca Cavalieri,4 Eleonora Ingrassia,4 Maria Russo,1,2 Alessio Piraino4 1Respiratory Unit for Continuity of Care, IRCCS, Ospedale Policlinico San Martino, Genova, Italy; 2Department of Internal Medicine
Braido F +6 more
doaj
Stopping long-acting beta2-agonists (LABA) for children with asthma well controlled on LABA and inhaled corticosteroids. [PDF]
BACKGROUND: Asthma is the most common chronic medical condition among children and is one of the most common causes of hospitalisation and medical visits.
Aalbers +59 more
core +1 more source
Benefit:Risk Profile of Budesonide in Obstructive Airways Disease [PDF]
Airway inflammation is a major contributing factor in both asthma and chronic obstructive pulmonary disease (COPD) and represents an important target for treatment.
Brattsand, Ralph +2 more
core +3 more sources
Inhaled corticosteroids for chronic obstructive pulmonary disease-the shifting treatment paradigm [PDF]
Chronic obstructive pulmonary disease (COPD) guidelines suggest using inhaled corticosteroids (ICS) in patients with severe airflow limitation or those at high risk of exacerbations.
Duerden M +8 more
core +2 more sources
Chronic obstructive pulmonary disease (COPD) is a condition characterised by poorly reversible airflow limitation that is generally progressive and causes serious disability.
Sakinatus Syarifah, Muhammad Amin
doaj +1 more source

