Results 101 to 110 of about 3,591 (213)

Long-acting beta-agonists in the management of chronic obstructive pulmonary disease: current and future agents [PDF]

open access: yes, 2010
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow limitation and debilitating symptoms. For patients with moderate-to-severe COPD, long-acting bronchodilators are the mainstay of therapy; as symptoms progress ...
Donald P Tashkin, Leonardo M Fabbri
core   +4 more sources

Bisoprolol and Bisoprolol-Valsartan Compatibility Studied by Differential Scanning Calorimetry, Nuclear Magnetic Resonance and X-Ray Powder Diffractometry [PDF]

open access: yes, 2014
Purpose The objective of this study was to evaluate the thermal behavior of crystalline and amorphous bisoprolol fumarate and its compatibility with amorphous valsartan.
Juan A. Aguilar   +3 more
core   +3 more sources

Efficacy and Safety of Budesonide/Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Japanese Patients with COPD: A Subgroup Analysis of the KRONOS Study

open access: yesInternational Journal of COPD, 2019
Masakazu Ichinose,1 Yasushi Fukushima,2 Yoshikazu Inoue,3 Osamu Hataji,4 Gary T Ferguson,5 Klaus F Rabe,6 Nobuya Hayashi,7 Hiroshi Okada,7 Mami Takikawa,7 Eric Bourne,8 Shaila Ballal,9 Kiernan DeAngelis,10 Magnus Aurivillius,11 Paul Dorinsky,8 Colin ...
Ichinose M   +14 more
doaj  

Assessment of drug permeability using a small airway microphysiological system

open access: yesFrontiers in Pharmacology
BackgroundThere is a need to reliably predict the permeability of inhaled compounds during the development of new and generic drugs. A small airway microphysiological system (MPS) that can recapitulate the pulmonary air-liquid interface (ALI) with ...
Robert M. Geiger   +18 more
doaj   +1 more source

A re-evaluation of the role of inhaled corticosteroids in the management of patients with chronic obstructive pulmonary disease [PDF]

open access: yes, 2015
Peer reviewedPublisher ...
D'Urzo, Anthony   +4 more
core   +2 more sources

Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis. [PDF]

open access: yes, 2014
BACKGROUND: Pharmacological therapy for chronic obstructive pulmonary disease (COPD) is aimed at relieving symptoms, improving quality of life and preventing or treating exacerbations.Treatment tends to begin with one inhaler, and additional therapies ...
Aalbers   +511 more
core   +1 more source

Stopping long-acting beta2-agonists (LABA) for adults with asthma well controlled by LABA and inhaled corticosteroids. [PDF]

open access: yes, 2015
BACKGROUND: Poorly controlled asthma often leads to preventable exacerbations that require additional medications, as well as unscheduled hospital and clinic visits.Long-acting beta2-agonists (LABA) are commonly given to adults with asthma whose symptoms
Aalbers   +47 more
core   +1 more source

Corrigendum

open access: yesInternational Journal of COPD, 2012
Tashkin DP, Doherty DE, Kerwin E, Matiz-Bueno CE, Knorr B, Shekar T, Banerjee S, Staudinger H. Efficacy and safety of a fixed-dose combination of mometasone furoate and formoterol fumarate in subjects with moderate to very severe COPD: results from a 52 ...
Tashkin DP   +7 more
doaj  

Determination of physical and chemical stability in pressurised metered dose inhalers: potential new techniques [PDF]

open access: yes, 2015
INTRODUCTION: Pressurised metered dose inhalers (pMDIs) are subject to rigorous physical and chemical stability tests during formulation. Due to the time and cost associated with product development studies, there is a need for online techniques to fast ...
Boyd, BJ   +4 more
core   +1 more source

Perspective on the Budgetary Impact of FP/FORM pMDI on Treatment and Management of Exacerbation in Moderate-to-Severe Asthma Patients in Singapore

open access: yesClinicoEconomics and Outcomes Research, 2020
Sebastien Boisseau,1 Murtaza Qasuri,1 Weng Tong Ho,1 Wrik Ghosh,2 Yacine Hadjiat1 1Mundipharma Singapore Holding Pte Limited, Singapore; 2Costello Medical Singapore Pte Ltd, SingaporeCorrespondence: Yacine HadjiatMundipharma Singapore Holding Pte Limited,
Boisseau S   +4 more
doaj  

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