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Fluticasone propionate/formoterol fumarate in fixed-dose combination for the treatment of asthma
Expert Review of Respiratory Medicine, 2014A new combination inhaler containing fluticasone, a potent inhaled corticosteroid (ICS), and formoterol, a long-acting β-agonist (LABA) with rapid onset and sustained bronchodilator effect, has been approved for treatment of persistent asthma in patients ≥12 years of age requiring combination ICS-LABA therapy.
David, Price, Elizabeth V, Hillyer
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Journal of the American Pharmacists Association
Chronic obstructive pulmonary disease (COPD) is a progressive illness characterized by persistent respiratory symptoms and restricted airflow, often owing to smoking and prolonged exposure to environmental irritants. COPD affects the pulmonary vasculature, lung parenchyma, and airways, leading to structural abnormalities such as emphysema.
Piyush Thathera +3 more
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Chronic obstructive pulmonary disease (COPD) is a progressive illness characterized by persistent respiratory symptoms and restricted airflow, often owing to smoking and prolonged exposure to environmental irritants. COPD affects the pulmonary vasculature, lung parenchyma, and airways, leading to structural abnormalities such as emphysema.
Piyush Thathera +3 more
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Expert Review of Clinical Pharmacology, 2020
Introduction: Treatment options for COPD have evolved rapidly in the last decade and inhaled bronchodilators have largely supplanted the use of oral bronchodilators because of their increased efficacy and excellent safety with topical delivery to the lung.
Ryan, Haley, Nita, Gupta, Sanjay, Sethi
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Introduction: Treatment options for COPD have evolved rapidly in the last decade and inhaled bronchodilators have largely supplanted the use of oral bronchodilators because of their increased efficacy and excellent safety with topical delivery to the lung.
Ryan, Haley, Nita, Gupta, Sanjay, Sethi
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Fluticasone Propionate/Formoterol Fumarate: A Review of Its Use in Persistent Asthma
Drugs, 2013The corticosteroid fluticasone propionate (fluticasone) and the long-acting β₂-adrenoceptor agonist formoterol fumarate (formoterol) have been combined in a single, pressurized, metered-dose, aerosol inhaler for the maintenance treatment of patients aged ≥12 years with persistent asthma.
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Pharmacokinetics and effects of formoterol fumarate in healthy human subjects after oral dosing
European Journal of Clinical Pharmacology, 1998To evaluate the effects of formoterol after oral administration on plasma eosinophils and plasma potassium in healthy subjects.Plasma concentrations of formoterol, peripheral eosinophil count and plasma potassium were determined during 7 h after oral administration of 168 microg of formoterol to eight healthy subjects. Descriptions of the concentration-
B T, van den Berg +2 more
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Quantitative nuclear magnetic resonance analysis of solid formoterol fumarate and its dihydrate
Journal of Pharmaceutical Sciences, 2003Carbon-13 cross-polarization magic-angle spinning nuclear magnetic resonance spectra of anhydrous formoterol fumarate and the dihydrate are presented, together with some relaxation time measurements. The latter enabled quantitation of mixtures of the anhydrate and dihydrate to be made.
David C, Apperley +3 more
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American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2002
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Sustained improvement in asthma with long-term use of formoterol fumarate.
Annals of allergy, 1993Inhaled formoterol fumarate, a long acting beta 2 agonist, produces bronchodilatation that is sustained for approximately 12 hours. To determine whether such bronchodilator effects are maintained and asthma control sustained during chronic administration, we monitored airflow indices and clinical control in 112 asthmatic patients who self administered ...
S, Kesten +9 more
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