Results 181 to 190 of about 3,591 (213)

Thermodynamic Stability and Crystal Structures for Polymorphs and Solvates of Formoterol Fumarate

Journal of Pharmaceutical Sciences, 2006
Polymorph screening of formoterol fumarate was performed in 12 solvents, followed by evaluations of thermodynamic stability. Three anhydrates, a dihydrate, a diethanolate, a diisopropanolate, and a dibensylalcoholate were found. The crystal structure of three solvated modifications and of the most stable anhydrate was investigated.
K, Jarring, T, Larsson, B, Stensland, I, Ymén   +3 more
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Compatibility and Aerosol Characteristic of Formoterol Fumarate Mixed with Other Nebulizing Solutions

Annals of Pharmacotherapy, 2008
Background: Patients with chronic obstructive pulmonary disease (COPO) are often given admixtures of nebulizable drugs to minimize the time of administration in treatment regimens. Objective: To evaluate the physicochemical compatibility and aerodynamic characteristics of formoterol fumarate 20 μg/2 mL when mixed or sequentially nebulized with ...
Samuel, Akapo, June, Gupta, Eloisa, Martinez, Chithra, McCrea, Liwen, Ye, Mark, Roach   +5 more
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Bioequivalence of Inhaled Formoterol Fumarate Assessed from Pharmacodynamic, Safety and Urinary Pharmacokinetic Data

Arzneimittelforschung, 2011
This paper deals with a crossover trial on healthy volunteers performed to obtain combined pharmacodynamic, safety and pharmacokinetic data in order to assess the bioequivalence of formoterol fumarate (CAS 43229-80-7) delivered by mono-dose dry powder inhalers, as test and reference.
MARZO A, MONTI NC, TETTAMANTI RA, CRIVELLI F, DAL BO L, MAZZUCCHELLI P, MEOLI A, PEZZUTO D, CORSICO, ANGELO GUIDO   +8 more
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Fluticasone propionate/formoterol fumarate in fixed-dose combination for the treatment of asthma

Expert Review of Respiratory Medicine, 2014
A new combination inhaler containing fluticasone, a potent inhaled corticosteroid (ICS), and formoterol, a long-acting β-agonist (LABA) with rapid onset and sustained bronchodilator effect, has been approved for treatment of persistent asthma in patients ≥12 years of age requiring combination ICS-LABA therapy.
David, Price, Elizabeth V, Hillyer
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Fluticasone Propionate/Formoterol Fumarate: A Review of Its Use in Persistent Asthma

Drugs, 2013
The corticosteroid fluticasone propionate (fluticasone) and the long-acting β₂-adrenoceptor agonist formoterol fumarate (formoterol) have been combined in a single, pressurized, metered-dose, aerosol inhaler for the maintenance treatment of patients aged ≥12 years with persistent asthma.
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Inhaled beclometasone dipropionate/formoterol fumarate extrafine fixed combination for the treatment of asthma

Expert Review of Respiratory Medicine, 2016
Inhaled therapy is often considered the cornerstone of asthma management and international guidelines recommend combination therapy of inhaled corticosteroids (ICS) and long-acting-beta2-agonists (LABA) in a large proportion of asthmatic patients. The effectiveness of ICS/LABA is dependent on the correct choice of device and proper inhalation technique,
CRISAFULLI, Ernesto, Zanini, Andrea, PISI, GIOVANNA, Pignatti, Patrizia, Poli, Gianluigi, Scuri, Mario, CHETTA, Alfredo Antonio   +6 more
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Disposition and metabolism of formoterol fumarate, a new bronchodilator, in rats and dogs

Xenobiotica, 1982
1. The disposition and metabolism of formoterol fumarate, a highly potent beta 2-adrenoceptor stimulant, were studied in rats and dogs. 2. After oral administration of [3H] formoterol fumarate to dogs, unchanged formoterol accounted for greater than 60% of the plasma radioactivity immediately after dosage; greater than 20% was due to the unchanged drug
H, Sasaki, H, Kamimura, Y, Shiobara, Y, Esumi, M, Takaichi, T, Yokoshima   +5 more
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Pharmacokinetics and effects of formoterol fumarate in healthy human subjects after oral dosing

European Journal of Clinical Pharmacology, 1998
To evaluate the effects of formoterol after oral administration on plasma eosinophils and plasma potassium in healthy subjects.Plasma concentrations of formoterol, peripheral eosinophil count and plasma potassium were determined during 7 h after oral administration of 168 microg of formoterol to eight healthy subjects. Descriptions of the concentration-
B T, van den Berg, M C, Braat, C J, van Boxtel   +2 more
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Formoterol fumarate.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2002
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Advantages of high-dose dual combination of beclomethasone dipropionate/formoterol fumarate

PULMONOLOGIYA
Bronchial asthma is a chronic inflammatory disease of the respiratory tract which requires a multifaceted approach to treatment. The results of modern studies of asthma treatment have shown that combination of beclomethasone dipropionate (BDP)/formoterol fumarate (FF) has a rapid bronchodilating effect, while improving control over asthma symptoms ...
S. K. Zyryanov, A. B. Strok, S. N. Avdeev   +2 more
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