Results 41 to 50 of about 3,527,229 (316)

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

New 30-Noroleanane Triterpenoid Saponins from Holboellia coriacea Diels

Molecules, 2016
Three new 30-noroleanane triterpenoid saponins, akebonoic acid 28-O-β-d-glucopyranosyl-(1′′→6′)-β-d-glucopyranosyl ester (1), akebonoic acid 28-O-(6′′-O-caffeoyl)-β-d-glucopyranosyl-(1′′→6′)-β-d-glucopyranosyl ester (Holboelliside A, 2) and 3β,20α,24 ...
Wenbing Ding, Ye Li, Guanhua Li, Hualiang He, Zhiwen Li, Youzhi Li   +5 more
doaj   +1 more source

Enzymatic interesterification to produce zero-trans and dialkylketones-free fats from rapeseed oil

Oilseeds and fats, crops and lipids, 2022
This study aims to evaluate the potential of applying enzymatic interesterification (EIE) to produce new healthy zero-trans high vitaminic content margarine fats, based on rapeseed oil (RO) only, with a specific focus on process-induced contaminants: the
Danthine Sabine, Closset Sébastien, Maes Jeroen, Mascrez Steven, Blecker Christophe, Purcaro Giorgia, Gibon Véronique   +6 more
doaj   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Antibody association in solution: cluster distributions and mechanisms

mAbs
Understanding factors that affect the clustering and association of antibodies molecules in solution is critical to their development as therapeutics. For 19 different monoclonal antibody (mAb) solutions, we measured the viscosities, the second virial ...
Sandi Brudar, Leonid Breydo, Elisha Chung, Ken A. Dill, Nasim Ehterami, Ketan Phadnis, Samir Senapati, Mohammed Shameem, Xiaolin Tang, Muhammmad Tayyab, Barbara Hribar-Lee   +10 more
doaj   +1 more source

Effects of DA-5513 on alcohol metabolism and alcoholic fatty liver in rats

Laboratory Animal Research, 2018
Hangover is characterized by a number of unpleasant physical and mental symptoms that occur after heavy alcohol drinking. In addition, consistently excessive alcohol intake is considered as a major reason causes liver disease.
Jae Young Yu, Hanh Thuy Nguyen, Chul Soon Yong, Hyoung Geun Park, Joon Ho Jun, Jong Oh Kim   +5 more
doaj   +1 more source

Statistical-mechanical formulation of Lyapunov exponents

, 2002
We show how the Lyapunov exponents of a dynamic system can in general be expressed in terms of the free energy of a (non-Hermitian) quantum many-body problem.
Anteneodo C, Antoni M, Arnold L, Balents L, Beck C, Benzi R, Crisanti A, Derrida B, Dressler U, Eckmann J-P, Efetov K B, Efetov K B, Firpo M-C, Gordhirsch I, Graham R, Jorge Kurchan, Latora V, Lima R, Livi L, Livi R, Marko? P, Oseledec V I, Parisi G, Ruelle D, Ruelle D, Schomerus H, Sinai Ya G, Sompolinsky H, Sorin Tanase-Nicola, Vallejos R O, Weigt M, Zinn-Justin J   +31 more
core   +1 more source

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

Combinatorial formulation of Ising model revisited

, 2003
In 1952, Kac and Ward developed a combinatorial formulation for the two dimensional Ising model which is another method of obtaining Onsager's formula for the free energy per site in the thermodynamic limit of the model.
da Costa, G. A. T. F., Maciel, A. L.
core   +2 more sources

Psychological Safety Among Interprofessional Pediatric Oncology Teams in Germany: A Nationwide Survey

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Psychological safety (PS) is essential for teamwork, communication, and patient safety in complex healthcare environments. In pediatric oncology, interprofessional collaboration occurs under high emotional and organizational demands. Low PS may increase stress, burnout, and adverse events.
Alexandros Rahn, Anna‐Lena Herbach, Christian Bock, Katharina Fleig, Urs Mücke   +4 more
wiley   +1 more source