Results 21 to 30 of about 18,956 (211)
NEW FORMYL PEPTIDE HAS THE STIMULATING PROPERTIES IN POINT OF IMMUNE SYSTEM CELLS [PDF]
Annals of Mechnikov's Institute, 2017 Introduction Tuberculosis infection (TBI) is still one of the major health problems, despite of global intensive medical and pharmaceutical efforts as it is known, in the majority of immunocompetent individuals TBI is repressed by immune system, and as a
Martynov A. V. +6 more
doaj +1 more source
FITC Conjugation Markedly Enhances Hepatic Clearance of N-Formyl Peptides. [PDF]
PLoS ONE, 2016 In both septic and aseptic inflammation, N-formyl peptides may enter the circulation and induce a systemic inflammatory response syndrome similar to that observed during septic shock.
Cristina Ionica Øie +4 more
doaj +1 more source
Life, 2022 Formyl peptide receptor type 2 (FPR2/ALX) belongs to the formyl peptide receptors (FPRs) family clustered on chromosome 19 and encodes a family of three Class A of G protein-coupled receptors (GPCRs).
Mariantonella Colucci +5 more
doaj +1 more source
Formyl peptide receptor 2 and heart disease
Seminars in Immunology, 2022 Formyl peptide receptor type 2 (FPR2) regulates the initiation and resolution phases of the inflammatory response. In the setting of heart injury and disease, dysregulated inflammation can potentiate maladaptive healing and pathological remodeling of the heart leading to cardiac dysfunction and failure.
John A, Lupisella +3 more
openaire +2 more sources
FPR1 (formyl peptide receptor 1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012 Review on FPR1 (formyl peptide receptor 1), with data on DNA, on the protein encoded, and where the gene is implicated.
Huang, J, Wang, JM
openaire +2 more sources
Медицинская иммунология, 2022 Formyl peptide receptors (FPRs) are an important part of innate immunity involved in antimicrobial phagocyte functions such as chemotaxis, secretory degranulation, and respiratory burst.
A. Mohammad +4 more
doaj +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Structural basis of ligand binding modes at the human formyl peptide receptor 2
Nature Communications, 2020 Formyl peptide receptors (FPRs) are GPCRs that play important roles in transducing chemotactic signals in phagocytes and mediating host-defense and inflammatory responses. Here the authors present the 2.8 Å crystal structure of human FPR2 in complex with
Tong Chen +12 more
doaj +1 more source
Honokiol suppresses formyl peptide-induced human neutrophil activation by blocking formyl peptide receptor 1 [PDF]
Scientific Reports, 2017 AbstractFormyl peptide receptor 1 (FPR1) mediates bacterial and mitochondrial N-formyl peptides-induced neutrophil activation. Therefore, FPR1 is an important therapeutic target for drugs to treat septic or sterile inflammatory diseases. Honokiol, a major bioactive compound of Magnoliaceae plants, possesses several anti-inflammatory activities.
Fu-Chao Liu +7 more
openaire +3 more sources
Divergent Annexin A1 expression in periphery and gut is associated with systemic immune activation and impaired gut immune response during SIV infection. [PDF]
, 2016 HIV-1 disease progression is paradoxically characterized by systemic chronic immune activation and gut mucosal immune dysfunction, which is not fully defined.
Dandekar, Satya +6 more
core +1 more source