Results 21 to 30 of about 9,630 (159)
Role of Formyl Peptide Receptors and β-Arrestin-1 in suPAR Signal Transduction in Mouse Podocytes: Interactions with αVβ3-Integrin [PDF]
CellsDryer Stuart E
exaly +2 more sources
FITC Conjugation Markedly Enhances Hepatic Clearance of N-Formyl Peptides. [PDF]
PLoS ONE, 2016 In both septic and aseptic inflammation, N-formyl peptides may enter the circulation and induce a systemic inflammatory response syndrome similar to that observed during septic shock.
Cristina Ionica Øie +4 more
doaj +1 more source
Life, 2022 Formyl peptide receptor type 2 (FPR2/ALX) belongs to the formyl peptide receptors (FPRs) family clustered on chromosome 19 and encodes a family of three Class A of G protein-coupled receptors (GPCRs).
Mariantonella Colucci +5 more
doaj +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Structural basis of ligand binding modes at the human formyl peptide receptor 2
Nature Communications, 2020 Formyl peptide receptors (FPRs) are GPCRs that play important roles in transducing chemotactic signals in phagocytes and mediating host-defense and inflammatory responses. Here the authors present the 2.8 Å crystal structure of human FPR2 in complex with
Tong Chen +12 more
doaj +1 more source
Медицинская иммунология, 2022 Formyl peptide receptors (FPRs) are an important part of innate immunity involved in antimicrobial phagocyte functions such as chemotaxis, secretory degranulation, and respiratory burst.
A. Mohammad +4 more
doaj +1 more source
Formyl peptide receptor 2 and heart disease
Seminars in Immunology, 2022 Formyl peptide receptor type 2 (FPR2) regulates the initiation and resolution phases of the inflammatory response. In the setting of heart injury and disease, dysregulated inflammation can potentiate maladaptive healing and pathological remodeling of the heart leading to cardiac dysfunction and failure.
John A, Lupisella +3 more
openaire +2 more sources
Molecular Neurodegeneration, 2012 Background Recent studies suggest that the chemotactic G-protein-coupled-receptor (GPCR) formyl-peptide-receptor-like-1 (FPRL1) and the receptor-for-advanced-glycation-end-products (RAGE) play an important role in the inflammatory response involved in ...
Slowik Alexander +7 more
doaj +1 more source
Formylated MHC Class Ib Binding Peptides Activate Both Human and Mouse Neutrophils Primarily through Formyl Peptide Receptor 1. [PDF]
PLoS ONE, 2016 Two different immune recognition systems have evolved in parallel to recognize peptides starting with an N-formylated methionine, and recognition similarities/differences between these two systems have been investigated.
Malene Winther +5 more
doaj +1 more source
Annexin A1 induces skeletal muscle cell migration acting through formyl peptide receptors. [PDF]
PLoS ONE, 2012 Annexin A1 (ANXA1, lipocortin-1) is a glucocorticoid-regulated 37-kDa protein, so called since its main property is to bind (i.e. to annex) to cellular membranes in a Ca(2+)-dependent manner.
Valentina Bizzarro +4 more
doaj +1 more source