Results 51 to 60 of about 9,630 (159)

Formyl peptide receptors are candidate chemosensory receptors in the vomeronasal organ [PDF]

Proceedings of the National Academy of Sciences, 2009
The identification of receptors that detect environmental stimuli lays a foundation for exploring the mechanisms and neural circuits underlying sensation. The mouse vomeronasal organ (VNO), which detects pheromones and other semiochemicals, has 2 known families of chemoreceptors, V1Rs and V2Rs.
Stephen D, Liberles, Lisa F, Horowitz, Donghui, Kuang, James J, Contos, Kathleen L, Wilson, Jessica, Siltberg-Liberles, David A, Liberles, Linda B, Buck   +7 more
openaire   +2 more sources

New formyl peptide has the stimulating properties in point of immune system cells

Annals of Mechnikov's Institute, 2019
Introduction Tuberculosis infection (TBI) is still one of the major health problems, despite of global intensive medical and pharmaceutical efforts as it is known, in the majority of immunocompetent individuals TBI is repressed by immune system, and as a
A Martynov, E Romanova, M Pohorila, O Shcherbak, T Sidorenko, N Igumnova, V Yukhimenko   +6 more
doaj  

Main‐chain polyfullerenes: Taking fullerene to the next dimension

Polymer International, EarlyView.
This short review appraises main‐chain polyfullerenes. Their slow development over 30 years has suddenly boomed with a rapid growth due to exciting developments in solar energy. Abstract This mini‐review gives an overview of the development, chemistry, properties and applications of main‐chain polyfullerenes.
Marco Antônio GB Gomes, Orisson Ponce Gomes, Patricia Targon Campana, Didier Bégué, Roger C Hiorns   +4 more
wiley   +1 more source

N-Formylated Peptide Induces Increased Expression of Both Formyl Peptide Receptor 2 (Fpr2) and Toll-Like Receptor 9 (TLR9) in Schwannoma Cells—An In Vitro Model for Early Inflammatory Profiling of Schwann Cells

Cells, 2020
Following nerve injury, disintegrated axonal mitochondria distal to the injury site release mitochondrial formylated peptides and DNA that can induce activation and inflammatory profiling of Schwann cells via formyl peptide receptor 2 (Fpr2) and toll ...
Andrea Korimová, Petr Dubový
doaj   +1 more source

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

Allergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan, Sofia Vlasova, Alicia Chenoweth, Debra H. Josephs, Heather J. Bax, Sophia N. Karagiannis   +5 more
wiley   +1 more source

Prebiotic aqueous reactions catalyzed by native nickel without hydrogen

The FEBS Journal, EarlyView.
Serpentinizing (H2‐producing) hydrothermal vents are candidate environments for metabolic origin. They generate highly reducing conditions that convert CO2 to formate and methane in abiotic reactions resembling reactions of the acetyl‐CoA pathway of CO2 fixation. They also contain natural catalysts. Native nickel (Ni0), like Fe0, Co0, and their alloys,
Carolina Garcia Garcia, Max Brabender, William F. Martin   +2 more
wiley   +1 more source

Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas

Scientific Reports, 2017
The development of metastases is a multistep process that requires the activation of physiological and biochemical processes that govern migration, invasion and entry of metastatic cells into blood vessels.
Maria Vincenza Carriero, Katia Bifulco, Vincenzo Ingangi, Susan Costantini, Giovanni Botti, Concetta Ragone, Michele Minopoli, Maria Letizia Motti, Domenica Rea, Giosuè Scognamiglio, Gerardo Botti, Claudio Arra, Gennaro Ciliberto, Antonello Pessi   +13 more
doaj   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Recovery from Cogwheel Rigidity and Akinesia and Improvement in Vibration Sense and Olfactory Perception following Removal of an Epoxy-Oleic Acid DNA Adduct

Case Reports in Medicine, 2017
The epoxy fatty acid cis-12,13-epoxy-oleic acid, which acts as a DNA adduct, may be generated during long-term storage of many seed oils, including those used in cooking, with frying oils and fried foods being a major source in the modern human diet ...
Jean A. Monro, John McLaren-Howard, Mussadiq Shah, Peter O. O. Julu, Basant K. Puri   +4 more
doaj   +1 more source

Targeting progressive multiple sclerosis: Toward mechanism‐informed precision medicine

Journal of Internal Medicine, Volume 300, Issue 3, Page 238-257, September 2026.
Abstract Multiple sclerosis has undergone a therapeutic revolution over the past three decades. Randomized clinical trials and real‐world data demonstrate that modern disease‐modifying therapies substantially reduce relapse rates and acute inflammatory activity detected by magnetic resonance imaging (MRI).
Fredrik Piehl, Gonçalo Castelo‐Branco, Maja Jagodic, Tomas Olsson   +3 more
wiley   +1 more source