Results 191 to 200 of about 592,256 (277)

Correction to "Multicenter Longitudinal Quality Assessment of MS-Based Proteomics in Plasma and Serum". [PDF]

J Proteome Res
Kardell O, Gronauer T, von Toerne C, Merl-Pham J, König AC, Barth TK, Mergner J, Ludwig C, Tüshaus J, Giesbertz P, Breimann S, Schweizer L, Müller T, Kliewer G, Distler U, Aljakouch K, Gomez-Zepeda D, Popp O, Qin D, Teupser D, Cox J, Imhof A, Küster B, Lichtenthaler SF, Krijgsveld J, Tenzer S, Mertins P, Coscia F, Hauck SM.   +28 more
europepmc   +1 more source

Mapping Charge Interactions in Intrinsically Disordered Proteins

Advanced Science, EarlyView.
This study presents analytical models to predict intrachain distances in intrinsically disordered proteins (IDPs), accounting for charge patterning, salt concentration, and electrostatic effects. Validated against single‐molecule FRET data, a minimal‐parameter polymer model is identified that captures key interactions and chain dimensions. These models
Michael Phillips, Andrea Holla, Magdalena Wojtas, Aritra Chowdhury, Andrea Sottini, Sebastian L. B. König, Natalie Mutter, Nick Lamb, Jonathan Huihui, Monika Lopko, Andrea Soranno, Daniel Nettels, Andrzej Ożyhar, Benjamin Schuler, Kingshuk Ghosh   +14 more
wiley   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

[Sex and gender differences in posttraumatic stress disorder: current evidence on etiology, trajectory and treatment]. [PDF]

Nervenarzt
Haering S, Meyer C, Knaevelsrud C, Engel S.   +3 more
europepmc   +1 more source

Unraveling Energy Flow Mechanisms in Semiconductors by Ultrafast Spectroscopy: Germanium as a Case Study

Advanced Science, EarlyView.
A multi‐technique pump‐probe setup capable of performing both transient reflectivity and time‐resolved Raman spectroscopy after ultrafast excitation, provides a comprehensive understanding of ultrafast electronic and phononic processes. Distinct decay rates for the temperature, frequency, and linewidth of the phonon mode in germanium are observed ...
Grazia Raciti, Begoña Abad, Riccardo Dettori, Raja Sen, Aswathi K. Sivan, Jose M. Sojo‐Gordillo, Nathalie Vast, Riccardo Rurali, Claudio Melis, Jelena Sjakste, Ilaria Zardo   +10 more
wiley   +1 more source

Vibration promotes catabolic activity in degenerated bovine intervertebral discs despite estrogen supplementation

Brain and Spine
G.Q. Teixeira, F. Figel, J.U. Jansen, M. Ahrens, F. Widmayer, H.J. Wilke, A. Ignatius, M. Haffner-Luntzer, C. Neidlinger-Wilke   +8 more
doaj   +1 more source

AutoQC-Bench: a diffusion model and benchmark for automatic quality control in high-throughput microscopy. [PDF]

Npj Imaging
Pan Z, Sonneck J, Nagel D, Hasenberg A, Gunzer M, Shi Y, Chen J.   +6 more
europepmc   +1 more source

From Sample to Mixed Reality: A Translational 3D MALDI Imaging Platform for Advanced 3D Spatial Omics Analysis of 3D Cell Culture Disease Models

Advanced Science, EarlyView.
A comprehensive technology platform enables high‐fidelity, volumetric MALDI imaging of 3D cell cultures by integrating custom embedding molds, a semi‐automated computational framework for 3D reconstruction, voxel‐instead of pixel‐based biomarker discovery, and immersive mixed reality data exploration.
Stefania Alexandra Iakab, Jonas Cordes, Thomas Enzlein, Florian Keller, Kevin Kastner, Theresa Mulholland, Björn Christian Fröhlich, Lars Gruber, James Lucas Cairns, Stefan Schmidt, Mathias Hafner, Richard Schneider, Johannes Betge, Frank Fischer, Julian Reichwald, Rüdiger Rudolf, Carsten Hopf   +16 more
wiley   +1 more source

Erratum zu: Messung der körperlichen Fitness in der NAKO Gesundheitsstudie – Methoden, Qualitätssicherung und erste deskriptive Ergebnisse. [PDF]

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
Kluttig A, Zschocke J, Haerting J, Schmermund A, Gastell S, Steindorf K, Herbolsheimer F, Hillreiner A, Jochem C, Baumeister S, Sprengeler O, Pischon T, Jaeschke L, Michels KB, Krist L, Greiser H, Schmidt G, Lieb W, Waniek S, Becher H, Jagodzinski A, Schipf S, Völzke H, Ahrens W, Günther K, Castell S, Kemmling Y, Legath N, Berger K, Keil T, Fricke J, Schulze MB, Loeffler M, Wirkner K, Kuß O, Schikowski T, Kalinowski S, Stang A, Kaaks R, Damms Machado A, Hoffmeister M, Weber B, Franzke CW, Thierry S, Peters A, Kartschmit N, Mikolajczyk R, Fischer B, Leitzmann M, Brandes M.   +49 more
europepmc   +1 more source

Cohort‐Scale Spatial Autocorrelation for Tumor Prediction in Mid‐Infrared Pathology and Spatial Biomarker Discovery Using MALDI Imaging Lipidomics

Advanced Science, EarlyView.
Computational annotation of various tissue types in heterogeneous samples such as colorectal cancer liver metastasis (CRLM) using spatial autocorrelation analysis on non‐destructive mid‐infrared (MIR) imaging data enabled correlative multimodal mass spectrometry imaging (MSI) for spatial investigation of lipid tumor marker candidates. The method can be
Miriam F. Rittel, Nikolas Ebert, Denis Abu Sammour, Sebastian Graf, Björn C. Fröhlich, Emrullah Birgin, Shad A. Mohammed, Nuh N. Rahbari, Axel Wellmann, Oliver Wasenmüller, Cleo‐Aron Weis, Stefan Schmidt, Carsten Hopf   +12 more
wiley   +1 more source