Results 81 to 90 of about 88,865 (291)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Secure Connectivity Probability of Multi‐hop Clustered Randomize‐and‐Forward Networks

open access: yesETRI Journal, 2017
This work investigates secure cluster‐aided multi‐hop randomize‐and‐forward networks. We present a hop‐by‐hop multi‐hop transmission scheme with relay selection, which evaluates for each cluster the relays that can securely receive the message.
Xiaowei Wang, Zhou Su, Guangyi Wang
doaj   +1 more source

Safe abstractions of data encodings in formal security protocol models [PDF]

open access: yes, 2014
When using formal methods, security protocols are usually modeled at a high level of abstraction. In particular, data encoding and decoding transformations are often abstracted away.
Pironti, Alfredo, Sisto, Riccardo
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Secure Transmission in SWIPT-Powered Two-Way Untrusted Relay Networks

open access: yesIEEE Access, 2018
In this paper, we investigate the secure transmission in two-way untrusted amplify-and-forward relay networks with simultaneous wireless information and power transfer (SWIPT).
Jiazhen Zhang   +3 more
doaj   +1 more source

A Practical Forward-Secure DualRing [PDF]

open access: yes, 2021
Ring signature allows a signer to generate a signature on behalf of a set of public keys, while a verifier can verify the signature without identifying who the actual signer is. In Crypto 2021, Yuen et al.
Atsuko Miyaji   +4 more
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Forward secure signatures on smart cards preliminary version

open access: yes, 2013
We introduce the forward secure signature scheme XMSS + and present an implementation for smart cards. It is based on the hash-based signature scheme XMSS. In contrast to the only previous implementation of a hash-based signature scheme on smart cards by
Wu, H.   +4 more
core   +2 more sources

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