Fluorine-Assisted Self-Assembly Triggers Peculiarities in Molecular Dynamics of a Polar Glass-Former. [PDF]
J Phys Chem BWojnarowska Z +5 more
europepmc +1 more source
Molecular basis of antibiotic sensing by the TetR family regulator CecR – a structural perspective
The FEBS Journal, EarlyView.Escherichia coli CecR, a member of the TetR family regulators, senses selected antibiotics and activates the expression of a putative drug efflux pump. Although present in many pathogenic Enterobacteriales strains, CecR remains poorly characterized. We present the first CecR crystal structure, which reveals a unique tunnel‐like ligand‐binding cavity ...
Agnieszka J. Pietrzyk‐Brzezinska +5 more
wiley +1 more source
Protocol for whole-tissue immunolabeling, optical clearing, and lightsheet imaging of c-Fos protein expression in unsectioned mouse brains. [PDF]
STAR ProtocFu K, Yang J.
europepmc +1 more source
The FEBS Journal, EarlyView.Ataxin‐1 is a polyglutamine protein associated with the etiology of spinocerebellar ataxia type 1 (SCA1) that has been recently found implicated in the risk of developing the autoimmune disorder multiple sclerosis (MS). Here, we took a conditional knockout approach to ablate ataxin‐1 exclusively in the B‐cell compartment and we found that this protein ...
Jonathan Jacob Carver +3 more
wiley +1 more source
Functional Beverages From Frankincense and <i>Pistacia atlantica</i>: A Natural Synbiotic Strategy for Managing Hyperlipidemia and Modulating Gut Microbiota. [PDF]
Food Sci NutrAlhelfi N +5 more
europepmc +1 more source
The FEBS Journal, EarlyView.Angiotensin I‐converting enzyme (ACE) contains two catalytic domains (nACE and cACE) and is a key therapeutic target for hypertension and cardiovascular disease. Current ACE inhibitors (ACEi) nonselectively inhibit both domains, causing adverse effects. Selective inhibition requires an understanding of domain‐specific binding.
Kyle S. Gregory +3 more
wiley +1 more source
Effect of suction stress on the strength of rupture zone and stability of landslide. [PDF]
Sci RepWang J, Su A, Liu Q, Zou Z.
europepmc +1 more source
Idiosyncratic Political Risk and Bad News Hoarding
Financial Review, EarlyView.ABSTRACT Managers may respond to greater political risk by suppressing unfavorable news from outsiders to manage investors’ perceptions about firm risk and protect their careers. However, they may also avoid engaging in bad news hoarding activities because exposure to political risk increases firm visibility and attracts greater scrutiny. Using a novel
Gonul Colak +2 more
wiley +1 more source
Efficacy and safety of intrathecal human umbilical cord-derived mesenchymal stromal cell therapy for bone cancer pain: a preclinical study. [PDF]
Stem Cell Res TherZhang J +5 more
europepmc +1 more source
A review of skin microbiome and new challenges to cosmetic microbiome‐friendly formulations
International Journal of Cosmetic Science, EarlyView.Microbiome‐friendly concepts offer new perspectives for a healthy relationship between cosmetic use and the skin microbiome, especially the interaction of non‐biotic cosmetic ingredients with the skin, requiring further studies to clarify the dynamics between the skin microbiome and different classes of cosmetic ingredients.
Yasmin Rosa Santos +3 more
wiley +1 more source