Results 101 to 110 of about 4,076 (169)

Genome-scale metabolic modelling of human gut microbes to inform rational community design. [PDF]

Gut Microbes
Molina Ortiz JP, McClure DD, Holmes A, Rice SA, Read MN, Shanahan ER.   +5 more
europepmc   +1 more source

Neuroinflammation drives apathy in cancer cachexia

Cancer Communications, EarlyView.
Bingjun Ha, Xuetao Cao
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

A molecularly defined brain circuit module for regulating panic-like defensive state. [PDF]

Nat Commun
Zhao M, Zhang L, Chen Z, Zhang S, Cheng X, Huang M, Li X, Gu H, Guan X, Geng D, Li Y, Tu Y, Xie Z, Zhang F, Ma H, Li X, Li D, Wu QF, Cao P.   +18 more
europepmc   +1 more source

Effectiveness of perampanel as the only adjunctive anti‐seizure medication in adults: Final results from the observational PERPRISE study in Germany

Epilepsia Open, EarlyView.
Abstract Objective The PERPRISE study (Study 509; NCT04202159) was a prospective, observational, non‐interventional study in a real‐world setting in Germany. This study was conducted to evaluate the effectiveness of perampanel as the only adjunctive treatment for 12 months in patients aged ≥18 years with focal to bilateral tonic–clonic seizures (FBTCS)
Bernhard J. Steinhoff, Tobias Goldmann, Edgar Kockelmann, Yaroslav Winter   +3 more
wiley   +1 more source

Taurine is a potential therapy for rheumatoid arthritis via targeting FOXO3 through cellular senescence and autophagy. [PDF]

PLoS One
Zheng Q, Lin R, Li Z, Zheng Q, Xu W.
europepmc   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Increased matrix stiffness promotes fibrogenesis of hepatic stellate cells through AP-1-induced chromatin priming. [PDF]

Commun Biol
Zhao W, Yuan W, Dong T, Qi W, Feng Z, Li C, Sun Y.   +6 more
europepmc   +1 more source

Multi‐Scale Evolution Mechanism of Water‐Conducting Fracture Zone in Deep‐Mining Hard Roof

Energy Science &Engineering, EarlyView.
ABSTRACT This study addresses the significant discrepancies in traditional methods for predicting the height of water‐conducting fracture zones in deep‐mining hard roofs, which can lead to catastrophic water inrush events. The 110,504 working face of Banji Coal Mine was chosen as the research site to systematically investigate the development ...
Yingfu Li, Linyang Bai, Hongwei Cai, Di Hu, Fangang Zeng   +4 more
wiley   +1 more source

Molecular characterization of PANoptosis-related genes in chronic kidney disease. [PDF]

PLoS One
Zhang WT, Ge HW, Wei Y, Gao JL, Tian F, Zhou EC.   +5 more
europepmc   +1 more source