Results 101 to 110 of about 3,808 (149)

Short-term social isolation acts on hypothalamic neurons to promote social behavior in a sex- and context-dependent manner. [PDF]

Elife
Zhao X, Chae Y, Smith D, Chen V, DeFelipe D, Sokol JW, Sadangi A, Tschida K.   +7 more
europepmc   +1 more source

A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.
ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada, Mary P. Choules, Frances A. Brightman, Shigeru Takeshita, Shinsuke Nakao, Nobuaki Amino, Takeshi Nakayama, Masato Takeuchi, Kanji Komatsu, Fernando Ortega, Hitesh Mistry, David Orrell, Christophe Chassagnole, Peter L. Bonate   +13 more
wiley   +1 more source

The Mechanism of the Nucleus Accumbens-Ventral Pallidum Pathway Mediated by Drug Withdrawal-Induced High-Seeking Motivation in Cocaine Addiction. [PDF]

Int J Mol Sci
Tan J, Meng Y, Du W, Jin L, Liang J, Shen F.   +5 more
europepmc   +1 more source

Modeling of Disease Progression of Type 2 Diabetes Using Real‐World Data: Quantifying Competing Risks of Morbidity and Mortality

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 606-615, March 2025.
ABSTRACT Type 2 diabetes (T2D) is a progressive metabolic disorder that could be an underlying cause of long‐term complications that increase mortality. The assessment of the probability of such events could be essential for mortality risk management. This work aimed to establish a framework for risk predictions of macrovascular complications (MVC) and
Hanna Kunina, Stefan Franzén, Maria C. Kjellsson   +2 more
wiley   +1 more source

Nonfragile Sliding Mode Control of Fractional‐Order Complex Networked Systems via Combination Event‐Triggered Approach

International Journal of Robust and Nonlinear Control, EarlyView.
ABSTRACT This work addresses the problem of developing a nonfragile sliding mode observer for fractional‐order complex networked systems (FO‐CNS) under stochastic network attacks. The proposed approach employs a combination of event‐triggered techniques. First, a nonfragile fractional‐order state observer is developed, enabling the design of a suitable
Xin Meng, Baoping Jiang, Hamid Reza Karimi   +2 more
wiley   +1 more source

A multi-dimensional validation strategy of pharmacological effects of Radix Isatidis Mixtures against the co-infection of Mycoplasma gallisepticum and Escherichia coli in poultry. [PDF]

Poult Sci
Jin X, Huo J, Yao Y, Li R, Sun M, Li J, Wu Z.   +6 more
europepmc   +1 more source

Resonant Raman Scattering Study of Strain and Defects in Chemical Vapor Deposition Grown MoS2 Monolayers

Small, EarlyView.
This work unifies the study of effects of local strain and disorder on the Raman and photoluminescence spectra of chemical vapor deposition (CVD) grown semiconducting 2D‐TMDs, shedding light on their influence on the frequency and intensity of second‐order acoustic Raman bands under resonant conditions.
Rafael N. Gontijo, Nathaniel Bunker, Samarra L. Graiser, Xintong Ding, Manuel Smeu, Ana Laura Elías   +5 more
wiley   +1 more source

An updated compendium and reevaluation of the evidence for nuclear transcription factor occupancy over the mitochondrial genome. [PDF]

PLoS One
Marinov GK, Ramalingam V, Greenleaf WJ, Kundaje A.   +3 more
europepmc   +1 more source

Controlling Droplet Evaporation in Aerosol Jet Printing to Understand and Mitigate Overspray

Small Science, EarlyView.
Saturating the sheath gas during aerosol jet printing limits aerosol‐phase evaporation, reducing overspray and improving overall print quality. This experimentally validates nonuniform sheath‐induced drying as a key mechanism during printing, with implications for high‐resolution patterning, electrical conductivity, and surface finish. This combination
Bella I. Guyll, Brayden L. Sanford, Cary L. Pint, Ethan B. Secor   +3 more
wiley   +1 more source

Amelioration of biased neuronal differentiation in humanized mouse model of valproic acid-induced autism by precisely targeted transcranial magnetic stimulation. [PDF]

Bioeng Transl Med
Hou Y, Zhao Y, Yang D, Feng T, Li Y, Li X, Liu Z, Yan X, Zhang H, Wu S, Liu X, Wang Y.   +11 more
europepmc   +1 more source