Results 181 to 190 of about 481 (199)

c-fos mRNA constitutive expression by mature human megakaryocytes.

Oncogene, 1992
By in situ hybridization with a c-fos probe, we have shown that human bone marrow megakaryocytes cultured in the presence of 20% aplastic anemia plasma constitutively express c-fos mRNA. At day 0, megakaryocytes are mostly immature and only 3% of them are labeled. The number of labeled cells reached 23% after 12 days of culture.
B, Panterne, J, Hatzfeld, J M, Blanchard, J P, Levesque, R, Berthier, M, Ginsbourg, A, Hatzfeld   +6 more
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Resistance of human fibroblasts to c-fos mediated transformation.

Oncogene, 1993
Overexpression of the proto-oncogene c-fos induces transformation of primary avian and established rodent mesenchymal cells and tumor development in transgenic mice. As overexpression of Fos was also found in several human tumors of mesenchymal origin, we were interested whether c-fos is a transforming protein for human cells.
M, Alt, R, Grassmann
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Expression of c-fos in human and murine multidrug-resistant cells.

Molecular Pharmacology, 1992
In both mouse sarcoma 180 and human KB cells selected for the multiple drug resistance (MDR) phenotype, there is an elevation in the steady state mRNA level of c-fos. There is no detectable gene amplification for c-fos, nor is there any significant change in the rate of mRNA transcription or degradation, suggesting that other factors are responsible ...
A, Bhushan, R, Abramson, J F, Chiu, T R, Tritton   +3 more
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Pulsatile and steady flow induces c‐fos expression in human endothelial cells

Journal of Cellular Physiology, 1993
AbstractThe effects of pulsatile and steady fluid flow on the mRNA levels of proto‐oncogenes c‐fos, c‐jun, and c‐myc in cultured human umbilical vein endothelial cells (HUVEC) were investigated. c‐fos mRNA levels in stationary cultures were very low. A 1 Hz pulsatile flow with an average shear stress of 16 dynes/cm2 induced a dramatic increase of c‐fos
Frangos, J. A., Li, N. Q., Hsieh, Hsyue-Jen   +2 more
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c-jun and c-fos are expressed by human megakaryocytes.

Experimental hematology, 1992
Expression of the main nuclear protooncogenes during terminal megakaryocyte (MK) differentiation is poorly understood. Because previous results have suggested that c-fos and c-jun protooncogenes are expressed in human leukemic cell lines induced to undergo megakaryocytic differentiation, we have analyzed the expression of these two protooncogenes in ...
M A, Mouthon, S, Navarro, A, Katz, J, Breton-Gorius, W, Vainchenker   +4 more
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Thyrotropin Receptor Autoantibodies Induce Human Thyroid Cell Growth and c-fosActivation*

The Journal of Clinical Endocrinology & Metabolism, 1991
Graves' disease encompasses hyperthyroidism and a diffuse goiter associated with autoantibodies to the TSH receptor (TRAb). Although the cause of the goiter formation has been attributed to TRAb, the limited growth pattern of human adult thyroid cells in vitro has caused such a conclusion to be based on studies of nonhuman thyroid cell growth.
G K, Huber, R, Safirstein, D, Neufeld, T F, Davies   +3 more
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MiR-146a targets Fos expression in human cardiac cells

2015
miR-146a is a microRNA whose transcript levels are induced in the heart upon activation of NF-κB, a transcription factor induced by proinflammatory molecules (such as TNF-α) that is strongly related to the pathogenesis of cardiac disorders. The main goal of this study consisted of studying new roles of miR-146a in cardiac pathological processes caused ...
Palomer, Xavier, Capdevila-Busquets, E., Botteri, G., Davidson, Mercy M., Rodríguez, Cristina, Martínez-González, José, Vidal, Francisco, Barroso, Emma, Chan, Tung O., Feldman, Arthur M., Vázquez-Carrera, Manuel, Universitat Autònoma de Barcelona   +11 more
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Effects of Human Leptin Fragments in Hypothalamic Nucleus C-Fos Expression

2001
The product of the ob gene is a protein hormone mainly secreted by the adipose tissue denoted leptin. Among many other effects, leptin provides signals to the brain about the amount of body fat stores and acts to reduce food intake and increase the energy expenditure.
Vani X. Oliveira, M. Terêsa M. Miranda, Jackson C. Bittencourt, Carol F. Elias, Antonio Miranda   +4 more
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Ternary Complex Formation at the Human c-fos Serum Response Element

1993
Quiescent cells can be stimulated to active growth by the addition of serum growth factors or mitogens. These proliferative signals activate an intracellular signalling pathway that leads to the rapid and transient transcriptional activation of a large family of genes, the so-called “immediate-early” genes (Almendrai et al. 1988; Bravo 1990). To attain
R. A. Hipskind, R. Janknecht, C. G. F. Mueller, A. Nordheim   +3 more
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Antigenicity of human hemoglobin Ao and Fo

Forensic Science, 1976
T. Fukae, I. Ohya, H. Suyama
openaire   +1 more source