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Evidence of vertical transmission of fowl adenovirus 8b in ducks
Veterinary Microbiology, 2023Fowl adenovirus mainly causes hydropericardium hepatitis syndrome (HHS), inclusion body hepatitis (IBH) and gizzard erosion (GE), etc. In 2015, the first outbreak of HHS was reported in broiler chickens in central China, followed by an outbreak in waterfowl.
Bingrong, Wu +9 more
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Rapid generation of fowl adenovirus 9 vectors
Journal of Virological Methods, 2015Fowl adenoviruses (FAdV) have the largest genomes of any fully sequenced adenovirus genome, and are widely considered as excellent platforms for vaccine development and gene therapy. As such, there is a strong need for stream-lined protocols/strategies for the generation of recombinant adenovirus genomes. Current genome engineering strategies rely upon
Yanlong Pei +4 more
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Emerging of a novel natural recombinant fowl adenovirus in China
Transboundary and Emerging Diseases, 2020Outbreaks of hydropericardium syndrome and inclusion body hepatitis caused by fowl adenovirus (FAdV) have occurred in China since June 2015, resulting in significant economic loss to poultry industry. In this study, a novel FAdV, designated as AH720, with recombination among serotype FAdV-8a and FAdV-8b was isolated and characterized in China.
Lu Lv +6 more
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Fowl Adenovirus-Based Vaccine Platform
2017Nonpathogenic fowl adenoviruses (FAdVs) are amenable for engineering multivalent vaccine platforms due to large stretches of nonessential DNA sequences in their genomes. We describe the generation of FAdV-9-based vaccine platforms by targeted homologous recombination in an infectious clone (pPacFAdV-9 or wild type FAdmid) containing the entire viral ...
Juan C, Corredor +2 more
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Vaccine, 2014
The number of clinical cases of inclusion body hepatitis (IBH) and hydropericardium-hepatitis syndrome (HHS) has been increasing, resulting in considerable economic losses in many countries. Currently, only fowl Adenovirus (FAdV) serotype 4 (FAdV-4) has been reported as the causative agent of HHS, whereas IBH can be caused by all 12 serotypes of FAdV ...
Dong-Hun Lee +2 more
exaly +3 more sources
The number of clinical cases of inclusion body hepatitis (IBH) and hydropericardium-hepatitis syndrome (HHS) has been increasing, resulting in considerable economic losses in many countries. Currently, only fowl Adenovirus (FAdV) serotype 4 (FAdV-4) has been reported as the causative agent of HHS, whereas IBH can be caused by all 12 serotypes of FAdV ...
Dong-Hun Lee +2 more
exaly +3 more sources
Immunopathogenesis and physical maps of fowl adenovirus serotype 9
Research in Veterinary Science, 1996Restriction endonuclease maps of the genome of fowl adenovirus (FAV) serotype 9 have been constructed for the restriction endonucleases NdeI, NotI and XbaI. The total size of the FAV-9 genome was estimated to be 44.5 kb pairs, consistent with previous reports that FAV genomes are approximately 10 kb larger than human adenovirus (HAV). The pathogenicity
K M, Erny, M, Sheppard, K J, Fahey
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Sequence comparison of the right end of fowl adenovirus genomes
Virus Genes, 2008The nucleotide sequence at the right end of the genomes of fowl adenoviruses (FAdVs) representing species groups C (FAdV-4 CA and FAdV-10 C-2B), D (FAdV-2 CA), and E (FAdV-8 CA) was determined and analyzed and compared to FAdV-1 (species group A virus) and FAdV-9 A-2A (species group B virus).
Juan Carlos, Corredor +3 more
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Sequence Analysis of the Left End of Fowl Adenovirus Genomes
Virus Genes, 2006Nucleotide sequence analysis of the left end of the genome of fowl adenoviruses (FAdV) representing species group C (FAdV-4 and -10), D (FAdV-2) and E (FAdV-8) were carried out, and the sequence data was compared to those of FAdV-1 (FAdV-A) and FAdV-9 (FAdV-D).
Juan Carlos, Corredor +2 more
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Veterinary Microbiology
Recently, the diseases caused by the infection of multiple serotypes of fowl adenoviruses (FAdVs) have spread worldwide and resulted in huge economic losses to the poultry industry. However, the commercial multivalent or bivalent vaccines against different serotypes of FAdV are not available. In this study, a novel recombinant FAdV-4, designated FAdV-4-
Shi, Liu +8 more
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Recently, the diseases caused by the infection of multiple serotypes of fowl adenoviruses (FAdVs) have spread worldwide and resulted in huge economic losses to the poultry industry. However, the commercial multivalent or bivalent vaccines against different serotypes of FAdV are not available. In this study, a novel recombinant FAdV-4, designated FAdV-4-
Shi, Liu +8 more
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The pros and cons of cytokines for fowl adenovirus serotype 4 infection
Archives of Virology, 2021Hepatitis-hydropericardium syndrome (HHS), caused by fowl adenovirus serotype 4 (FAdV-4), has spread on chicken farms worldwide, causing huge economic losses. Currently, the exact mechanism of pathogenesis of FAdV-4 remains unknown. Despite the severe inflammatory damage observed in chickens infected with pathogenic FAdV-4, few studies have focused on ...
Baiyu Wang, Huifang Guo, Jun Zhao
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