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Metabolomic Profiling Reveals New Insight of Fowl Adenovirus Serotype 4 Infection [PDF]

open access: yesFrontiers in Microbiology, 2022
Highly pathogenic fowl adenovirus serotype 4 (FAdV-4) is the causative agent of hydropericardium syndrome (HPS), which is characterized by pericardial effusion and hepatitis, and is one of the foremost causes of economic losses to the poultry industry ...
Haiying Ma, Yujuan Niu
doaj   +5 more sources

Pathogenicity and cytokine gene expression pattern of a serotype 4 fowl adenovirus isolate. [PDF]

open access: yesPLoS ONE, 2013
Hydropericardium-hepatitis syndrome (HHS), a recently emerged disease of chickens, is caused by some strains of fowl adenovirus serotype 4 (FAdV-4). In this study, a Canadian FAdV-4 isolate, designated as FAdV-4 ON1, was evaluated for pathogenicity after
Helena Grgić   +3 more
doaj   +5 more sources

Identification of a novel immunological epitope on Hexon of fowl adenovirus serotype 4 [PDF]

open access: yesAMB Express, 2021
Fowl adenovirus serotype 4 (FAdV-4), the causative agent of hepatitis-hydropericardium syndrome (HHS), distributed widely in the poultry farms in China. Hexon is one of the major capsid proteins associated with viral species or serotypes.
Jingyi Liu   +4 more
doaj   +5 more sources

Fowl adenovirus serotype-4 induces autophagy via the AMPK-mTOR signaling pathway during viral invasion of host cells [PDF]

open access: yesPoultry Science
Fowl adenovirus serotype 4 (FAdV-4) is the primary pathogen responsible for avian hepatitis-hydropericardium syndrome (HHS), which poses a significant threat to the poultry industry.
Hongnuan Wang   +10 more
doaj   +3 more sources

Pathogenesis of Hypervirulent Fowl Adenovirus Serotype 4: The Contributions of Viral and Host Factors [PDF]

open access: yesViruses, 2019
Since 2015, severe outbreaks of hepatitis-hydropericardium syndrome (HHS), caused by hypervirulent fowl adenovirus serotype 4 (FAdV-4), have emerged in several provinces in China, posing a great threat to poultry industry. So far, factors contributing to
Zeng Wang, Jun Zhao
doaj   +4 more sources

Design and Identification of a Novel Antiviral Affinity Peptide against Fowl Adenovirus Serotype 4 (FAdV-4) by Targeting Fiber2 Protein. [PDF]

open access: yesViruses, 2023
Outbreaks of hydropericardium hepatitis syndrome caused by fowl adenovirus serotype 4 (FAdV-4) with a novel genotype have been reported in China since 2015, with significant economic losses to the poultry industry.
Chen X   +10 more
europepmc   +3 more sources

A rapid, ultrasensitive, and highly specific method for detecting fowl adenovirus serotype 4 based on the LAMP-CRISPR/Cas12a system [PDF]

open access: yesPoultry Science
Fowl adenovirus serotype 4 (FAdV-4) is the causative agent of hydropericardium hepatitis syndrome in chickens, which causes severe economic impact to the poultry industry.
Kezong Qi, Xiangjun Song
exaly   +3 more sources

Fiber-2, not Fiber-1, is the principal protective immunogen of fowl adenovirus serotype 4: insights from a comparative efficacy study of chimeric virus-based inactivated vaccines [PDF]

open access: yesPoultry Science
Fowl adenovirus serotype 4 (FAdV-4) uniquely encodes two fiber proteins (fiber-1 and fiber-2), while FAdV-8b possesses only one. Although our previous study showed that an inactivated vaccine based on a chimeric virus with FAdV-4′s fiber-1 replaced by ...
Panpan Yang   +14 more
doaj   +3 more sources

Pathology and Molecular Epidemiology of Fowl Adenovirus Serotype 4 Outbreaks in Broiler Chicken in Abu Dhabi Emirate, UAE [PDF]

open access: yesVeterinary Sciences, 2022
Background: Fowl adenovirus serotype 4 (FAdV-4), causing inclusion body hepatitis (IBH) and hydropericardium hepatitis syndrome (HPS), is responsible for the significant economic losses in poultry industry worldwide. This study describes FAdV disease and
Hassan Zackaria Ali Ishag   +8 more
doaj   +3 more sources

Chicken Interferon-Alpha and -Lambda Exhibit Antiviral Effects against Fowl Adenovirus Serotype 4 in Leghorn Male Hepatocellular Cells. [PDF]

open access: yesInt J Mol Sci
Hydropericardium hepatitis syndrome (HHS) is primarily caused by fowl adenovirus serotype 4 (FAdV-4), causing high mortality in chickens. Although vaccination strategies against FAdV-4 have been adopted, HHS still occurs sporadically.
Lai J   +9 more
europepmc   +3 more sources

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