Fowl adenovirus serotype 4 enters leghorn male hepatocellular cells via the clathrin-mediated endocytosis pathway [PDF]
Hepatitis-hydropericardium syndrome (HHS) induced by fowl adenovirus serotype-4 (FAdV-4) has caused large economic losses to the world poultry industry in recent years.
Ting Wang +9 more
doaj +3 more sources
RACK1 inhibits fowl adenovirus serotype 4 replication by targeting the viral protein Hexon for ubiquitin-proteasome degradation [PDF]
Fowl adenovirus serotype 4 (FAdV-4), the most pathogenic member of the genus Aviadenovirus, within the family Adenoviridae, primarily induces hepatitis-hydropericardium syndrome (HHS), leading to high morbidity and mortality in chickens.
Wei Li +9 more
doaj +3 more sources
Pathogenicity and molecular characteristics of fowl adenovirus serotype 4 with moderate virulence in Guangxi Province, China [PDF]
The GX2020-019 strain of fowl adenovirus serotype 4 (FAdV-4) was isolated from the liver of chickens with hydropericardium hepatitis syndrome in Guangxi Province, China, and was purified by plaque assay three times.
You Wei +11 more
doaj +3 more sources
The Knob Domain of the Fiber-1 Protein Affects the Replication of Fowl Adenovirus Serotype 4. [PDF]
Fowl adenovirus serotype 4 (FAdV-4) outbreaks have caused significant economic losses in the Chinese poultry industry since 2015. The relationships among viral structural proteins in infected hosts are relatively unknown. To explore the role of different
Li X +8 more
europepmc +5 more sources
Differential innate immune responses to fowl adenovirus serotype 4 infection in Leghorn male hepatocellular and chicken embryo fibroblast cells. [PDF]
Fowl adenovirus serotype 4 (FAdV-4) infections result in substantial economic losses in the poultry industry. Recent findings have revealed that FAdV-4 significantly suppresses the host immune response upon infection; however, the specific viral and host
Hou X +11 more
europepmc +3 more sources
Hypervirulent fowl adenovirus serotype 4 elicits early innate immune response and promotes virus-induced cellular autophagy in the spleen. [PDF]
The recent emergence of hepatitis-hydropericardium syndrome caused by highly pathogenic fowl adenovirus serotype 4 (FAdV-4) has resulted in significant economic losses to the poultry industry.
Zhu C +8 more
europepmc +3 more sources
The Role of Hexon Amino Acid 188 Varies in Fowl Adenovirus Serotype 4 Strains with Different Virulence [PDF]
Hepatitis-hydropericardium syndrome (HHS) induced by fowl adenovirus serotype 4 (FAdV-4) has caused huge economic losses to poultry industries. The key genes responsible for different virulence of FAdV-4 strains are not fully elucidated. Previous studies
Baiyu Wang, Zeng Wang, Jun Zhao
exaly +4 more sources
Serological and Pathogenic Analyses of Fowl Adenovirus Serotype 4 (FAdV-4) Strain in Muscovy Ducks [PDF]
Hydropericardium hepatitis syndrome (HHS) is a lethal disease caused by Fowl adenovirus serotype 4(FAdV-4) that mainly infects 3- to 6-week-old broiler chicks.
Xianglong Yu +23 more
doaj +4 more sources
Detection and differentiation of fowl adenovirus serotype 4 and duck adenovirus 3 using high resolution melting curve assay [PDF]
Fowl adenovirus type 4 (FAdV-4) and duck adenovirus type 3 (DAdV-3) are the causative agents of clinical diseases in poultry and have caused considerable economic losses to the waterfowl industry in China.
Shuyu Chen +8 more
doaj +3 more sources
Epidemiological investigation and fiber gene genetic analysis of fowl adenovirus serotype 4 from 2017 to 2021 in Yunnan Province, China. [PDF]
Importance Through the epidemiological survey of fowl adenovirus serotype 4 (FAdV-4) in poultry and wild birds in Yunnan Province from 2017 to 2021, this study provides a scientific basis for the prevention and control of FAdV-4 in the region. Currently,
Xue X, Zhang Z, Yang Q, Wang W, Song J.
europepmc +2 more sources

