Results 51 to 60 of about 12,816,028 (152)

Antiviral and Virucidal Activities of Camptothecin on Fowl Adenovirus Serotype 4 by Blocking Virus Replication. [PDF]

Front Cell Infect Microbiol, 2022
Fowl adenovirus serotype 4 (FAdV-4) caused hepatitis–hydropericardium syndrome in poultry and caused huge economic losses to the poultry industry. At present, antiviral drugs have not been reported to be effective against this virus, and new treatment methods are urgently needed to treat FAdV-4.
Yin D, Yin L, Wang J, Shen X, Dai Y, Zhao R, Hu X, Hou H, Zhang D, Wang G, Qi K, Pan X.   +11 more
europepmc   +4 more sources

Altering the Ad5 packaging domain affects the maturation of the Ad particles [PDF]

, 2011
We have previously described a new family of mutant adenoviruses carrying different combinations of attB/attP sequences from bacteriophage PhiC31 flanking the Ad5 packaging domain.
Alba Fernández, Raúl, Raul Alba, Assumpcio Bosch, Chillon Miguel, Philomena Ostapchuk, Cots Dan, Hearing Patrick, Hearing, P., Alba, R., Ostapchuk Philomena, Bosch i Merino, Assumpció, Ostapchuk, Philomena, Alba Raul, Bosch Assumpcio, Miguel Chillon, Ostapchuk, P., Cots i Rabella, Dan, Cots, D., Chillón Rodríguez, Miguel, Chillon, M., Patrick Hearing, Hearing, Patrick, Bosch, A., Dan Cots   +23 more
core   +2 more sources

The Knob Domain of the Fiber-1 Protein Affects the Replication of Fowl Adenovirus Serotype 4. [PDF]

Microorganisms
Fowl adenovirus serotype 4 (FAdV-4) outbreaks have caused significant economic losses in the Chinese poultry industry since 2015. The relationships among viral structural proteins in infected hosts are relatively unknown. To explore the role of different parts of the fiber-1 protein in FAdV-4-infected hosts, we truncated fiber-1 into fiber-1-Δ1 (73–205
Li X, Xie Z, Wei Y, Xie Z, Wu A, Luo S, Xie L, Li M, Zhang Y.   +8 more
europepmc   +4 more sources

FAdV-4 induces more severe inflammatory responses compared to FAdV-8b

Poultry Science
Multiple infections, either single or mixed, involving pathogens such as serotype 4 fowl adenovirus (FAdV-4) and serotype 8b fowl adenovirus (FAdV-8b), have been observed in numerous laying hens in China, leading to severe liver damage.
Qinqin Sun, Xingfen Lei, Lianshun Zhang, Zilong Cheng, Sidang Liu, Qiang Fu   +5 more
doaj   +1 more source

Integrating Serological and Molecular Data to Characterize Fowl Adenovirus Associated With Inclusion Body Hepatitis in Broiler Chickens From Malaysia

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
This study revealed the active circulation of fowl adenoviruses in broiler farms in Sabah, Malaysia. FAdV‐8b and FAdV‐11 were identified in flocks with IBH lesions, accompanied by high antibody titres in unvaccinated birds. Phylogenetic analysis showed close relationships with global strains, highlighting the need for enhanced surveillance and control ...
Md. Safiul Alam Bhuiyan, Babu Kanti Nath, Lum Mok Sam, Krishnan Nair Balakrishnan, Suman Das Gupta, Subir Sarker   +5 more
wiley   +1 more source

The Role of Hexon Amino Acid 188 Varies in Fowl Adenovirus Serotype 4 Strains with Different Virulence

Microbiology Spectrum, 2022
Hepatitis-hydropericardium syndrome (HHS) induced by fowl adenovirus serotype 4 (FAdV-4) has caused huge economic losses to poultry industries. The key genes responsible for different virulence of FAdV-4 strains are not fully elucidated. Previous studies
Baiyu Wang, Congcong Song, Panpan Yang, Mingzhen Song, Shiyi Zhao, Qilong Qiao, Zeng Wang, Jun Zhao   +7 more
doaj   +1 more source

Risk Ranking of Microbiological Hazards in Food (2015–2019)

Food Risk Assess Europe, Volume 4, Issue 3, July 2026.
Abstract Microbiological food safety risks arise from pathogens that can contaminate food at different points along the food chain. Exposure to these hazards can result in illnesses that can vary widely in severity and duration, depending on factors such as the specific pathogen involved, the amount of the pathogen ingested, and the susceptibility of ...
Ms Chloe Glennon, Lisa O’Connor, Kevin Burke, Lauren Russell, Shaun Smith, Declan Bolton, Theo de Waal, Patricia Garvey, Montserrat Gutierrez, Noel McCarthy, Lois O’Connor, Helen O’Shea, Geraldine Duffy   +12 more
wiley   +1 more source

Hydropericardium syndrome caused by fowl adenovirus serotype 4 in replacement pullets

Journal of Veterinary Medical Science, 2019
Hydropericardium syndrome (HPS) is one of the important emerging diseases causing huge losses to the poultry industry. It affects mainly 3- to 6-week-old broiler chickens and rarely occurs in breeding and laying flocks. Recently, an HPS case was recorded with a sudden heavy mortality in a 100-day-old laying flock. A fowl adenovirus serotype 4 (FAdV-4),
CHEN, Zhen, SHI, Shaohua, QI, Baoming, LIN, Su, CHEN, Cuiteng, ZHU, Chunhua, HUANG, Yu   +6 more
openaire   +3 more sources

Table_1_Antiviral and Virucidal Activities of Camptothecin on Fowl Adenovirus Serotype 4 by Blocking Virus Replication.docx

, 2022
Fowl adenovirus serotype 4 (FAdV-4) caused hepatitis–hydropericardium syndrome in poultry and caused huge economic losses to the poultry industry. At present, antiviral drugs have not been reported to be effective against this virus, and new treatment ...
Lei Yin (300551), Xiaomiao Hu (12414613), Xuehuai Shen (12414607), Xiaocheng Pan (5471537), Ruihong Zhao (414073), Kezong Qi (5010956), Danjun Zhang (12414616), Jieru Wang (179734), Yin Dai (12414610), Guijun Wang (1687741), Dongdong Yin (10914503), Hongyan Hou (482201)   +11 more
core   +1 more source

Visual detection of fowl adenovirus serotype 4 via a portable CRISPR/Cas13a-based lateral flow assay

, 2023
The widespread occurrence of fowl adenovirus serotype 4 (FAdV-4)-induced hepatitis-hydropericardium syndrome (HHS) has led to significant economic losses for the poultry industry.
Lei Yin (300551), Xuehuai Shen (12414607), Xiaocheng Pan (5471537), Ruihong Zhao (414073), Kezong Qi (5010956), Jieru Wang (179734), Yin Dai (12414610), Dongdong Yin (10914503)   +7 more
core   +1 more source