Results 71 to 80 of about 12,816,028 (152)

Rapid Identification and Differential Detection of Infectious Bursal Disease Virus by an Innovative ARMS‐qRT‐PCR Assay

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Infectious bursal disease (IBD), caused by IBD virus (IBDV), is a major threat to the poultry industry, with the cocirculation of multiple genotyping strains complicating the diagnosis and control. Since the differences of antigenicity among different genotyping and their differences with the commonly used vaccine strains, rapid and accurate ...
Weiwei Wang, Yuanzheng Qiao, Jiafeng Wu, Ruiyang Kong, Yan Zhang, Jun Shi, Jinnan Chen, Zhiyuan Wang, Huimin Zhao, Tianchao Wei, Teng Huang, Jianni Huang, Meilan Mo, Xiumiao He, Ping Wei, Nanhua Chen   +15 more
wiley   +1 more source

Chicken Infectious Anemia Virus Markedly Enhances the Pathogenicity of Infectious Bronchitis Virus–Infected Chickens

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Chicken infectious anemia virus (CIAV) and infectious bronchitis virus (IBV) represent two of the most economically significant pathogens in the global poultry production. In recent years, coinfections involving CIAV and IBV have become increasingly prevalent in clinical scenarios across Southern China and globally.
Hao Chen, Shuangshuang Ma, Liuyang Yuan, Hongchun Yang, Shijun Xu, Shufeng Feng, Yaping Wang, Aobo Xu, Xiaoran Xuan, Ziqi Ling, Yang Li, Hongbin Si, Gonghe Li, Changbo Ou, Fabian Lean   +14 more
wiley   +1 more source

Analysis of Adenovirus-Host Interactions to Improve Recombinant Adenoviral Vectors for Gene Therapy [PDF]

, 2011
Recombinant adenoviral vectors are among the most commonly used vehicles in gene therapy. Replication-deficient adenoviruses include early generation adenoviruses, which are deleted in less than three adenoviral genes, and the high-capacity adenoviruses (
Rauschhuber, Christina
core   +1 more source

Prevalence and Molecular Characterization of FAdV‐4 Isolated in Fujian Province, Southeast China During 2023–2025

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Fowl adenovirus (FAdV) serotype 4 (FAdV‐4) is a significant pathogen causing hepatitis–hydropericardium syndrome (HHS) in poultry, which can cause severe economic losses to the global poultry industry. Molecular epidemiological investigation of FAdV‐4 has not been conducted in Fujian province, southeast China. In this study, we collected 219 samples of
Youlin Chen, Ziyue Wang, Dingping Bai, Zhen Chen, Cuiteng Chen, Xi Cai, Guanghua Fu, Chunhe Wan, Yu Huang, Chunhua Zhu, Nan-hua Chen   +10 more
wiley   +1 more source

Penton-dodecahedron of fowl adenovirus serotype 4 as a vaccine candidate for the control of related diseases [PDF]

Vaccine, 2019
In some serotypes of adenovirus (Ad), the penton base and attached trimeric fiber assemble into dodecameric virus-like particles called penton-dodecahedron (Pt-Dd), which can be internalized and used to deliver the vaccine antigens and drugs. Fowl adenovirus serotype 4 (FAdV-4) is an important pathogen, causing seriously economic loss to poultry ...
Xinglong Wang, Qiuxia Tang, Li Qiu, Zengqi Yang   +3 more
openaire   +2 more sources

Identification of chicken CAR homology as a cellular receptor for the emerging highly pathogenic fowl adenovirus 4 via unique binding mechanism

Emerging Microbes and Infections, 2020
Since 2015, the prevalence of severe hepatitis-hydropericardium syndrome, which is caused by the novel genotype fowl adenovirus serotype 4 (FAdV-4), has increased in China and led to considerable economic losses.
Qing Pan, Jing Wang, Yulong Gao, Qi Wang, Hongyu Cui, Changjun Liu, Xiaole Qi, Yanping Zhang, Yongqiang Wang, Kai Li, Li Gao, Aijing Liu, Xiaomei Wang   +12 more
doaj   +1 more source

Genomic Characterization of an Emergent Cross‐Border Recombinant Duck Plague Virus With High Pathogenicity and Reduced Vaccine Efficacy in Guangxi, China

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Duck plague virus (DPV) is a major pathogen causing recurrent outbreaks in waterfowl. This study reports the comprehensive characterization of a novel DPV strain, designated GXGG240520, isolated from clinically diseased ducks in Guangxi, China. The strain was confirmed as a virulent DPV by PCR targeting the UL2 gene (1002 bp) and exclusion of other ...
Songlin Yang, Shijun Xu, Kairu Wang, Chao Liu, Hongchun Yang, Liuyang Yuan, Shuangshuang Ma, Huayan Xie, Zhimin Zhang, Gonghe Li, Hongbin Si, Kun Ning, Changbo Ou, Linzhu Ren   +13 more
wiley   +1 more source

Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants. [PDF]

, 1993
Delivery of genes via receptor-mediated endocytosis is severely limited by the poor exit of endocytosed DNA from the endosome. A large enhancement in delivery efficiency has been obtained by including human adenovirus particles in the delivery system ...
Malt Cotlen, Kurt Zatloukal, Max, Wagner, E., L. Birnstiel, Wagner, Ernst, Birnstiel, Max L., Ernst Wagner, Cotten, Matt, Zatloukal, Kurt, Cotten, M., Zatloukal, K., Birnstiel, M.L.   +12 more
core  

Pathogenicity and Bioinformatics Analysis of Two GI‐13 Infectious Bronchitis Virus Strains in China

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Despite long‐term vaccination and control efforts, infectious bronchitis virus (IBV) remains a major threat to the global poultry industry, largely due to its high prevalence and extensive genetic diversity. This study aimed to characterize two novel GI‐13 (4/91‐like) IBV field strains, CK/CH/JS/2302 and CK/CH/AH/2307, isolated from H120‐vaccinated ...
Juan Jin, Li Zhao, Yingjun Lv, Endong Bao, Nan-hua Chen   +4 more
wiley   +1 more source

Aviadenovirus structure: A highly thermostable capsid in the absence of stabilizing proteins.

PLoS Pathogens
High-resolution structural studies have mainly focused on two out of the six adenovirus genera: mastadenoviruses and atadenoviruses. Here we report the high-resolution structure of an aviadenovirus, the poultry pathogen fowl adenovirus serotype 4 (FAdV ...
Marta Pérez-Illana, Anna Schachner, Mercedes Hernando-Pérez, Gabriela N Condezo, Alberto Paradela, Marta Martínez, Roberto Marabini, Michael Hess, Carmen San Martín   +8 more
doaj   +1 more source