Results 51 to 60 of about 5,621 (166)

Identification of SF-1 and FOXL2 and Their Effect on Activating P450 Aromatase Transcription via Specific Binding to the Promoter Motifs in Sex Reversing Cheilinus undulatus

Frontiers in Endocrinology, 2022
The giant wrasse Cheilinus undulatus is a protogynous socially hermaphroditic fish. However, the physiological basis of its sex reversal remains largely unknown.
Xinxin Ji, Shaoyang Bu, Yi Zhu, Yi Wang, Xin Wen, Feibiao Song, Jian Luo   +6 more
doaj   +1 more source

A novel classification of testicular sex cord‐stromal tumours from the Testicular Sex Cord‐Stromal Tumour (TESST) group: a collaboration of the Genitourinary Pathology Society (GUPS) and the International Society of Urological Pathology (ISUP)

Histopathology, Volume 89, Issue 4, Page 638-649, October 2026.
The TESST classification of testicular sex cord‐stromal tumours was agreed upon by consensus based on the best available evidence. The picture shows the members of the TESST group and delegates of GUPS and ISUP present in‐person at the first meeting of the group held at Johns Hopkins Hospital (Baltimore, 2024). Aims Testicular sex cord‐stromal tumours (
Andres M. Acosta, Felix Bremmer, John C. Cheville, Maurizio Colecchia, Eva Comperat, Kristine Cornejo, Dilek E. Baydar, Anthony J. Gill, Maria del Pilar Gonzalez‐Peramato, Sounak Gupta, Michelle S. Hirsch, Muhammad T. Idrees, Chia‐Sui Kao, Fiona MacLean, Andres Matoso, Rohit Mehra, Santosh Menon, Kvetoslava Michalova, Sambit K. Mohanty, Miguel Reyes‐Mugica, Maria Rosaria Raspollini, Ankur R. Sangoi, Lynette M. Sholl, Stephanie Siegmund, Satish K. Tickoo, Toyonori Tsuzuki, Thomas M. Ulbright, Sean R. Williamson, Asli Yilmaz, Daniel M. Berney   +29 more
wiley   +1 more source

Western blot confirming FOXL2 overexpression in COV434.

, 2012
A clear 45 kDa band in seen in lysates from wildtype and mutant FOXL2 overexpression. This band is absent in control lysates, and similar staining of vimentin across all three lysates confirms FOXL2 overexpression.
Cristin G. Print (130977), Andrew N. Shelling (130982), Hiromitsu Araki (130974), Roseanne Rosario (130971)   +3 more
core   +1 more source

Sexual Development of the Hermaphroditic Scallop Argopecten irradians Revealed by Morphological, Endocrine and Molecular Analysis

Frontiers in Cell and Developmental Biology, 2021
Simultaneous or functional hermaphrodites possessing both ovary and testis at the same time are good materials for studying sexual development. However, previous research on sex determination and differentiation was mainly conducted in gonochoristic ...
Huilan Wei, Wanru Li, Tian Liu, Yajuan Li, Liangjie Liu, Ya Shu, Lijing Zhang, Shi Wang, Shi Wang, Shi Wang, Qiang Xing, Qiang Xing, Lingling Zhang, Lingling Zhang, Zhenmin Bao, Zhenmin Bao, Zhenmin Bao   +16 more
doaj   +1 more source

Polyphenism Through RNA Chemical Modifications

Molecular Ecology, Volume 35, Issue 19, October 2026.
ABSTRACT Polyphenism, the capacity of a single genotype to produce discrete phenotypes in response to environmental cues, has long served as a model for understanding developmental plasticity. While classical studies have highlighted hormonal signalling and transcription‐factor‐driven gene regulatory networks that mediate these environmentally induced ...
Ralf Schneider, Ehsan Pashay Ahi
wiley   +1 more source

Conditional strategies to study gene function during gonadal development in mammals. [PDF]

, 2008
Sexual development in mammals involves a complex cascade of genetic events. These begin with a cell fate decision, whether to make Sertoli or follicle cells, that gives rise to the development of a male or female gonad, which is controlled by the testis ...
Tye, A.J.
core  

FOXL2 impairment in human disease

, 2012
<i>FOXL2</i> encodes a forkhead transcription factor that plays important roles in the ovary during development and in post-natal, adult life. Here, we focus on the clinical consequences of <i>FOXL2</i> impairment in human disease.
Elfride De Baere, De Baere, Elfride, Verdin, Hannah, Hannah Verdin   +3 more
core   +1 more source

Advanced Granulosa Cell Tumors of the Ovary: A Review with a Focus on Current and Novel Therapeutic Approaches [PDF]

Journal of Immunotherapy and Precision Oncology
Granulosa cell tumor (GCT) is the most common nonepithelial ovarian malignancy. Still, it is considered rare, with a paucity of high-level evidence guiding management, particularly in the metastatic setting.
Mohamad A. Salkeni, Sarah Shin, Naoko Takebe, Sally Stevens, Alice Chen   +4 more
doaj   +1 more source

Cooperative Effects of FOXL2 with the Members of TGF-β Superfamily on FSH Receptor mRNA Expression and Granulosa Cell Proliferation from Hen Prehierarchical Follicles. [PDF]

PLoS ONE, 2015
Forkhead box L2 (FOXL2) is a member of the forkhead nuclear factor 3 gene family and plays an essential role in ovarian growth and maturation in mammals.
Ning Qin, Xian-Cong Fan, Xiao-Xing Xu, Thobela Louis Tyasi, Shi-Jun Li, Ying-Ying Zhang, Man-Li Wei, Ri-Fu Xu   +7 more
doaj   +1 more source

Cell line specific expression of FOXL2 targets.

, 2012
Each point represents a single probeset. Signal intensities have been calculated for each probeset by averaging the signal intensities from the three control samples from the COV434 and KGN array data. Coloured points (purple, green and yellow) represent
Cristin G. Print (130977), Andrew N. Shelling (130982), Hiromitsu Araki (130974), Roseanne Rosario (130971)   +3 more
core   +1 more source