Results 161 to 170 of about 106,447 (316)

An increase in CD4+CD25+FOXP3+ regulatory T cells in tumor-infiltrating lymphocytes of human glioblastoma multiforme1 [PDF]

, 2006
Abdeljabar El Andaloussi, Maciej S. Lesniak   +1 more
openalex   +1 more source

TOPK Inhibition Promotes Anti‐Tumor Immunity Via eIF4F Complex Mediated STAT1 Translation in Gastric Cancer

Advanced Science, EarlyView.
This study identifies TOPK as a dual‐function target in gastric cancer: it drives tumor cell proliferation and migration, and under IFN‐γ stimulation, phosphorylates eIF4F complex component eIF4A1 to enhance STAT1 mRNA translation, thereby promoting PD‐L1/IDO1‐mediated tumor immunometabolic evasion.
Junbing Chen, Longtao Huangfu, Gangjian Wang, Xueying Wang, Huanbo Zhu, Qian Yao, Cong Chen, Xiaohuan Tang, Ting Guo, Biao Fan, Xingyang Liu, Qingda Li, Zining Liu, Ying Hu, Tianze Sun, Jiafu Ji, Xiaofang Xing   +16 more
wiley   +1 more source

Human FoxP3⁺CD4⁺ regulatory T cells: their knowns and unknowns [PDF]

, 2011
Makoto Miyara, Shimon Sakaguchi
openalex   +1 more source

A fresh look at a neglected regulatory lineage: CD8+Foxp3+ Regulatory T cells

, 2022
Adrian Liston, Meryem Aloulou
openalex   +1 more source

Multifunctional Nano Immunostimulant: Overcoming Immunosuppressive Microenvironment for Antitumor Immunotherapy

Advanced Science, EarlyView.
A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo, Wenda Zhong, Huishuang Zhao, Yueying An, Xinyu Dong, Zhengbo Li, Shuangfeng Qin, Guangzhao Xu, Xiangguo Yue, Xudong Wang, Wen Sun, Zhe‐Sheng Chen, Weiguo Song, Liuya Wei, Fahui Li   +14 more
wiley   +1 more source

Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination

Advanced Science, EarlyView.
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi, Colby J. Agostino, Jinwei Huang, Toshitha Kannan, Niklas Laenger, Jennifer Londregan, Katlyn Lederer, Michaela Helble, Nicole Bedanova, Cory Livingston, Ebony N. Gary, Madison McCanna, Marta Tarquis Medina, Rumi Habib, Ignacio Rodriguez Relaño, Ivan Maillard, Ami Patel, David Allman, Andrew Kossenkov, Amelia Escolano, Daniel W. Kulp, David. B. Weiner   +21 more
wiley   +1 more source

Impacts of rs7528684 (-169T/C) on <i>FCRL3</i>, <i>FOXP3</i>, and <i>IL-35</i> gene expressions and IgG-RF correlation: insights into the pathogenesis of rheumatoid arthritis. [PDF]

Front Genet
Mohamed Muzammil S, Asha Devi S.
europepmc   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Constitutively Active Stat5b Expression in Dendritic Cells Enhances Treg-Mediated Elimination of Autoreactive CD8⁺ T Cells in Autoimmune Diabetes. [PDF]

Int J Mol Sci
Khongorzul P, Khan FU, Levasseur D, Gris D, Amrani A.   +4 more
europepmc   +1 more source

1.6 – 00161 HIV-1 Antisense Transcripts are frequent in FOXP3-negative Treglike cells expressing markers of persistence in vivo during acute HIV- 1 infection

Malika Hale, Gautam Kundu, A. Geretz, Philip K. Ehrenberg, R. Clifford, Merlin L. Robb, C. Sacdalan, Somchai Sriplienchan, N. Phanuphak, S. Vasan, R. Thomas   +10 more
openalex   +1 more source