Results 191 to 200 of about 199,492 (387)

Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells [PDF]

, 2005
Manuela Battaglia, Angela Stabilini, Maria-Grazia Roncarolo   +2 more
openalex   +1 more source

Bronchus-associated lymphoid tissue–resident Foxp3+ T lymphocytes prevent antibody-mediated lung rejection [PDF]

, 2019
Alexander S. Krupnick, Alice Y. Tong, Andrew E. Gelman, Ankit Bharat, Baddoura, Brian W. Wong, Chyi S. Hsieh, Daniel Kreisel, Francine L. Kelly, Hiemann, Hsi-Min Hsiao, Jason M. Gauthier, Jon H. Ritter, Li, Linh Vuong, Onyema, Ramsey R. Hachem, Ryuji Higashikubo, Satona Tanaka, Scott M. Palmer, Varun Puri, Vu Van, Wenjun Li, William M. Baldwin   +23 more
core   +2 more sources

Single‐Cell Transcriptome Profiling Reveals Conserved IFNγ‐IL8 Signaling‐Induced Antibacterial Neutrophil States during Bacterial Infection

Advanced Science, EarlyView.
SummaryThis study constructs a single‐cell immune atlas of Nile tilapia across multiple time points during Streptococcus agalactiae infection, revealing dynamic immune cell responses and subtype transitions. It identifies a conserved IFNr‐STAT1‐IL8 axis driving il8+ neutrophils activation and antibacterial function, supported by cross‐species ...
Xue Zhai, Minghao Zhang, Kang Li, Wei Li, Xiaolong Li, Wa Gao, Zhaosheng Sun, Dan Huang, Songqian Huang, Mingli Liu, Zhichao Wu, Jun Zou, Liangbiao Chen, Jialong Yang, Peng Hu   +14 more
wiley   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

Developmental regulation of Foxp3 expression during ontogeny [PDF]

, 2005
Jason D. Fontenot, James Dooley, Andrew G. Farr, Alexander Y. Rudensky   +3 more
openalex   +1 more source

Viral‐Directed Augmentation of Kupffer Cell Cross‐Presentation Provokes Antitumor Immunity Against Liver Metastasis

Advanced Science, EarlyView.
Targeting Kupffer cells (KC) with a single intravenous infusion of the oncolytic virus VSV‐M51R rather than VSV‐WT induces effective tumor regression in various types of liver metastatic cancers in mice. VSV‐M51R promotes KC proliferation and enhances their antigen cross‐presentation capacity without compromising viability, leading to the induction of ...
Chen Chen, Qing Zhang, Jiajia Li, Xia Zhou, Daxing Gao, Lu Li, Dabing Huang, Jizhou Wang, Zhutian Zeng   +8 more
wiley   +1 more source

TGF-β regulatesin vivoexpansion of Foxp3-expressing CD4⁺CD25⁺regulatory T cells responsible for protection against diabetes

, 2004
Yufeng Peng, Yasmina Laouar, Ming O. Li, E. Allison Green, Richard A. Flavell   +4 more
openalex   +1 more source

Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease [PDF]

, 2005
Emmanuel Zorn, Haesook T. Kim, Stephanie J. Lee, Blair H. Floyd, Despina Litsa, Sankari Arumugarajah, Roberto Bellucci, Edwin P. Alyea, Joseph H. Antin, Robert J. Soiffer, Jerome Ritz   +10 more
openalex   +1 more source

Do all Foxp3+ Tregs require Foxp3 for suppression?

American Journal of Transplantation, 2022
openaire   +2 more sources

Cryo‐Inactivated Cancer Cells Derived Magnetic Micromotors for Tumor Immunotherapy

Advanced Science, EarlyView.
Cryo‐inactivated cancer cell‐based magnetic micromotors are developed for synergistic tumor immunotherapy via magnetic targeting. These micromotors can induce ferroptosis and immunogenic cell death, deliver tumor antigens, and activate the Mn2+‐dependent cGAS‐STING pathway. The system effectively suppresses tumor progression, recurrence, and metastasis,
Qingfei Zhang, Gaizhen Kuang, Wenzhao Li, Yuanjin Zhao   +3 more
wiley   +1 more source