Results 231 to 240 of about 167,256 (310)

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Eos plays a critical role in Treg homeostasis and modulates the function of recirculating thymic Tregs in the control of Treg development. [PDF]

Cell Rep
Xie X, Thornton AM, Tanwar S, Korty P, Wells AC, Segrist E, Teijeiro A, Rivera CA, Wei D, Chen X, Zhu J, Khleborodova A, Hill T, Markowitz TE, Smelkinson M, Kabat J, Veres T, Schwartz OM, Otaizo-Carrasquero F, Gardina P, Shamsaddini A, Martens C, Cho K, Lin CC, Khillan JS, Levin Y, Wu Y, Shevach EM.   +27 more
europepmc   +1 more source

Forkhead box P3 ( FOXP3 ) [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

Cutaneous Squamous Cell Carcinoma Amongst Solid Organ Transplant Recipients: A Systematic Review of Molecular Alterations

JEADV Clinical Practice, EarlyView.
ABSTRACT Background As solid organ transplantation becomes more prevalent, more patients are living on long‐term immunosuppression, greatly increasing the risk of cutaneous squamous cell carcinoma (cSCC). Although significant improvements have been achieved in the treatment of cSCC, further studies are needed to identify the specific protein expression
William Murray, Robin Caird, Michael O'Connor, Ciara Drumm, Emma O'Hora, Franklin Crossen, Aoife Lally, Aurelie Fabre, Roisin Dolan   +8 more
wiley   +1 more source

Spatial immune cell architecture after gastric cancer surgery predicts prognosis. [PDF]

World J Gastrointest Surg
Yang HJ, Liu B.
europepmc   +1 more source

NLRP3 inflammasome regulates Th17/Treg cell balance in experimental autoimmune myocarditis. [PDF]

Biochem Biophys Rep
Su L, Qu N, Chen L, Lin Y, Mo H, Huang Y.   +5 more
europepmc   +1 more source

Radiotherapy and Immune System Interactions Historical Perspectives and Clinical Advancements

Molecular Carcinogenesis, EarlyView.
ABSTRACT Radiotherapy (RT) has evolved significantly since its inception from treating benign conditions to becoming a cornerstone of cancer treatment. This review examines the complex interactions between RT and the immune system, highlighting its diverse effects on various immune cell populations, and exploring emerging strategies to enhance ...
Safiy Yahia, Ayman J. Oweida, Houda Bahig, Daniel Taussky   +3 more
wiley   +1 more source

Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer

Medicine Bulletin, EarlyView.
ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei, Yunli Xu, Tianjiao Zhang, Shuyu Xu, Haonan Wang, Yuan Wang, Xinxin Xie, Xiaolong Liang   +7 more
wiley   +1 more source

Prognostic relevance of specific TIL (CD4+, CD8+, and FOXP3 + T-cell infiltrates) in triple-negative breast cancer: short- and long-term outcomes. [PDF]

Breast Cancer
Caramelo O, Almeida V, Fidalgo A, Cipriano A, Almeida-Santos T.   +4 more
europepmc   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source