Results 241 to 250 of about 199,492 (387)

Novel non-coding FOXP3 transcript isoform associated to potential transcriptional interference in human regulatory T cells. [PDF]

RNA Biol
Cases M, Ritter N, Rincon-Arevalo H, Kroh S, Adam A, Kirchner M, Moradian H, Gossen M, Dzamukova M, Manukyan A, Landthaler M, Kressler C, Hauser AE, Depledge DP, Polansky JK, Chang HD.   +15 more
europepmc   +1 more source

FOXP3 Identifies Regulatory CD25^brightCD4⁺ T Cells in Rheumatic Joints [PDF]

, 2006
Duojia Cao, Ola Börjesson, P. Larsson, Anna Rudin, Iva Gunnarsson, Lars Klareskog, Vivianne Malmström, Christina Trollmo   +7 more
openalex   +1 more source

Prolonged inhaled allergen exposure can induce persistent tolerance [PDF]

, 2007
Joos, Guy, Maes, Tania, Tournoy, Kurt, Van Hove, Chris   +3 more
core   +2 more sources

A tolerogenic plasmid inhibits autoantibody production triggered by immunization with human peptidyl arginine deiminase 4.

Arthritis &Rheumatology, Accepted Article.
Objectives Rheumatoid arthritis (RA) is usually preceded and likely mediated by autoantibodies to citrullinated proteins (ACPAs) that recognize citrulline residues on multiple proteins. Conversion of arginine into citrulline is performed by enzymes called peptidyl arginine deiminases (PADs).
Philippe P. Pagni, Vijetha Kumar, Nathalie C. Lambert, Eva Frison, Herve Luche, Marielle Mello, Magali Torres, Johnna D. Wesley, Matthias von Herrath, Jean Roudier, Isabelle Auger   +10 more
wiley   +1 more source

Hypomethylating therapy mitigates acute allograft rejection in a murine lung transplant model. [PDF]

Front Transplant
Yarnoff KM, Daccarett-Bojanini WN, Villabona-Rueda AF, Sollmann M, D'Alessio FR, Dodd-O JM.   +5 more
europepmc   +1 more source

Butyrate, IL‐4, and EP4 Receptors: A Triad of Colorectal Homeostasis, Protecting Against Onset of Cancer and IBD?

BioEssays, EarlyView.
The two safety factors, butyrate and IL‐4, may be important external and internal factors, respectively, for maintaining homeostasis by blocking not only the development of colorectal cancer but also the onset of IBD via reducing/controlling expression levels of EP4 receptors.
Hiromichi Fujino
wiley   +1 more source

SIRT7 ameliorates Th17/Treg imbalance by desuccinylation of STAT3 to improve immune thrombocytopenia. [PDF]

Clin Transl Immunology
Ge J, Zhang X, Tang F, Liu Y.
europepmc   +1 more source

Engineering antibodies with cancer‐associated binding sites

BMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian, Yumeng Pan, Yingchun Zhang, Fangling Wang, Zejun Wang   +4 more
wiley   +1 more source

A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the tumor microenvironment. [PDF]

Oncotarget
Buszko M, Jones M, Chempati S, Morina L, Ward K, Habte H, Dziegielewski M, Shevach EM.   +7 more
europepmc   +1 more source

Foxp3⁺CD25^–CD4 T cells constitute a reservoir of committed regulatory cells that regain CD25 expression upon homeostatic expansion

, 2005
Santiago Zelenay, Thiago Lopes‐Carvalho, Íris Caramalho, Maria Francisca Moraes‐Fontes, Manuel Rebelo, Jocelyne Demengeot   +5 more
openalex   +1 more source