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Helios is critical for Treg effector differentiation in adipose autoimmunity. [PDF]
Thornton AM +11 more
europepmc +1 more source
Predicting recurrence risk after neoadjuvant therapy in breast cancer: a single-center retrospective cohort study integrating residual cancer burden and immune microenvironment features. [PDF]
Zhao Z, Deng R, Bai L, Duan X, Yi J.
europepmc +1 more source
Phenotypic Characteristics of B-Cell Subsets in Children with Allergic Diseases. [PDF]
Lipińska-Opałka A +5 more
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FOXP3 is a transcription factor necessary and sufficient for induction of the immunosuppressive functions in regulatory T lymphocytes. Its expression was first considered as specific of this cell type, but FOXP3 can also be transiently expressed in T-cell antigen receptor-activated human nonregulatory T cells.
Gregoire Mignot +2 more
exaly +3 more sources
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Polymorphism of the ovine FOXP3 gene (FOXP3)
Veterinary Immunology and Immunopathology, 2011FOXP3 is a transcription factor predominantly expressed in CD4(+) CD25(+) thymocytes and CD4(+) CD25(+) peripheral T cells. It has been reported that variation in the FOXP3 gene (FOXP3) could cause impaired immune regulation. Using PCR-SSCP, variation in exon 4, exon 9-10 and exon 13-14 of ovine FOXP3, covering three functional domains (a proline rich ...
Guo, Yang +2 more
openaire +2 more sources
Nature Immunology, 2017
By switching its partners, FoxP3 segregates into functional and non-functional transcriptional complexes.
David Bending, Masahiro Ono
openaire +2 more sources
By switching its partners, FoxP3 segregates into functional and non-functional transcriptional complexes.
David Bending, Masahiro Ono
openaire +2 more sources

