Results 261 to 270 of about 168,700 (307)

Graph neural network modeling of spatial tumor-immune interactions identifies prognostic cellular niches in non‑small cell lung cancer. [PDF]

NPJ Precis Oncol
Hoebel KV, Lindsay JR, Altreuter J, Alessi JV, Weirather JL, Dryg I, Giobbie-Hurder A, Li Z, Yu KH, Awad MM, Rodig SJ, Lotter W.   +11 more
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The inhibition of miR-125b-5P prevented Treg differentiation through activating STAT3/HIF-1α pathway in PBMCs of ankylosing spondylitis. [PDF]

Arthritis Res Ther
Yin W, Luo B, Cheng H, Xie X, Wu F, Wang W, Zhou P, Cui X, Yu H.   +8 more
europepmc   +1 more source

Extracellular vesicles derived from hADSCs rescue acute pancreatitis by carrying <i>p</i>-STK3 to regulate Treg differentiation. [PDF]

iScience
Xie R, Xiao G, Yang K, Wang X, Chen C, Zhou T, Chen Y, Chen E, Yang Z, Fei J, Xu D.   +10 more
europepmc   +1 more source

A novel FOXP3 gene variant causing neonatal diabetes and fatal enteropathy. [PDF]

Ann Pediatr Endocrinol Metab
Kumar M, Venkatesan R, Kc N, Bala A, Dayal D.   +4 more
europepmc   +1 more source

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Polymorphism of the ovine FOXP3 gene (FOXP3)

Veterinary Immunology and Immunopathology, 2011
FOXP3 is a transcription factor predominantly expressed in CD4(+) CD25(+) thymocytes and CD4(+) CD25(+) peripheral T cells. It has been reported that variation in the FOXP3 gene (FOXP3) could cause impaired immune regulation. Using PCR-SSCP, variation in exon 4, exon 9-10 and exon 13-14 of ovine FOXP3, covering three functional domains (a proline rich ...
Guo, Yang, Huitong, Zhou, Jon G H, Hickford   +2 more
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FoxP3 partners up

Nature Immunology, 2017
By switching its partners, FoxP3 segregates into functional and non-functional transcriptional complexes.
David Bending, Masahiro Ono
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Human FOXP3 and tumour microenvironment

Immunology, 2022
AbstractThe tumour microenvironment (TME) is a complex system composed of cancer cells, stromal cells and immune cells. Regulatory T cells (Tregs) in the TME impede immune surveillance of tumours and suppress antitumor immune responses. Transcription factor forkhead box protein 3 (FOXP3) is the main marker of Tregs, which dominates the function of ...
Jia Wang, Ruining Gong, Chenyang Zhao, Ke Lei, Xiaoyuan Sun, He Ren   +5 more
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Functional Analysis of FOXP3

Annals of the New York Academy of Sciences, 2008
Tolerance to self antigens is established in two ways: first in the thymus through the deletion of thymocytes expressing self‐reactive T cell receptors; and second, in the periphery through multiple mechanisms involving deletion, anergy, and suppression.
Jane H, Buckner, Steven F, Ziegler
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FOXP3+ regulatory T cells: control of FOXP3 expression by pharmacological agents

Trends in Pharmacological Sciences, 2011
Naturally arising CD4(+)CD25(+) regulatory T cells (Tregs), which specifically express the forkhead family transcription factor FOXP3, are essential for the maintenance of immunological self-tolerance and immune homeostasis. Tregs can suppress the activation, proliferation and effector function of other lymphocytes in physiological and pathological ...
Naganari, Ohkura, Masahide, Hamaguchi, Shimon, Sakaguchi   +2 more
openaire   +2 more sources