Estimation of free water-corrected microscopic fractional anisotropy [PDF]
Water diffusion anisotropy MRI is sensitive to microstructural changes in the brain that are hallmarks of various neurological conditions. However, conventional metrics like fractional anisotropy are confounded by neuron fiber orientation dispersion, and
Nico J. J. Arezza +6 more
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Dopamine content in the basal ganglia is strongly associated with the degree of dopaminergic neuron loss in the substantia nigra pars compacta. Symptoms of Parkinson's disease might not arise until more than 50% of the substantia nigra pars compacta is ...
Lan-xiang Liu +8 more
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An Introduction to Kurtosis Fractional Anisotropy. [PDF]
Neuroradiology and imaging-based diagnostics in general have a dire need for scan techniques with improved microstructural sensitivity for detection of subtle tissue alterations in early disease phases or for diagnostics of diseases that are currently simply radiologically invisible.
Hansen B.
europepmc +5 more sources
White matter fractional anisotropy decreases precede hyperintensities in Alzheimer's disease. [PDF]
The associations of β-amyloid (Aβ) and tau deposition with white matter (WM) degeneration in Alzheimer's disease (AD) remain inadequately elucidated. We investigate baseline and longitudinal changes of microstructural fractional anisotropy (FA) and macrostructural white matter hyperintensities (WMHs) and their relationships with Aβ and tau positron ...
Sun P +21 more
europepmc +3 more sources
Microscopic Fractional Anisotropy Detects Cognitive Training-Induced Microstructural Brain Changes. [PDF]
Cognitive training-induced neuroplastic brain changes have been reported. This prospective study evaluated whether microscopic fractional anisotropy (μFA) derived from double diffusion encoding (DDE) MRI could detect brain changes following a 4 week cognitive training.
Li X +6 more
europepmc +6 more sources
Sciatic nerve fractional anisotropy and neurofilament light chain protein are related to sensorimotor deficit of the upper and lower limbs in patients with type 2 diabetes. [PDF]
Kender Z +14 more
europepmc +3 more sources
Connectomics modeling of regional networks of white-matter fractional anisotropy to predict the severity of young adult drinking. [PDF]
Li Y +8 more
europepmc +2 more sources
Assessment of a Reliable Fractional Anisotropy Cutoff in Tractography of the Corticospinal Tract for Neurosurgical Patients. [PDF]
Wende T +7 more
europepmc +3 more sources
Correlation Analysis of Acute Psychotic Symptom Domain Severity and Fractional Anisotropy of Brain White Matter Tracts in Schizophrenia. [PDF]
Ushakov VL +5 more
europepmc +3 more sources
Potential Pitfalls of Using Fractional Anisotropy, Axial Diffusivity, and Radial Diffusivity as Biomarkers of Cerebral White Matter Microstructure. [PDF]
Figley CR +5 more
europepmc +3 more sources

