Results 1 to 10 of about 184,231 (271)
Modulation of fracture healing by the transient accumulation of senescent cells
eLife, 2021 Senescent cells have detrimental effects across tissues with aging but may have beneficial effects on tissue repair, specifically on skin wound healing. However, the potential role of senescent cells in fracture healing has not been defined.
Dominik Saul +7 more
doaj +1 more source
From Brittle to Ductile Fracture in Disordered Materials [PDF]
, 2010 We introduce a lattice model able to describe damage and yielding in heterogeneous materials ranging from brittle to ductile ones. Ductile fracture surfaces, obtained when the system breaks once the strain is completely localized, are shown to correspond
Clara B. Picallo +4 more
core +3 more sources
Trials, 2021 Background There are more than 300,000 hip fractures yearly in the USA with mortality rates of 20% within 1 year. The treatment of osteoporotic fractures is a major challenge as bone quality is poor, and healing is expected to delay due to the impaired ...
Ronald Man Yeung Wong +8 more
doaj +1 more source
Development of an ischemic fracture healing model in mice
Acta Orthopaedica, 2022 Background and purpose: In fracture healing, ischemia caused by vascular injuries, chronic vascular diseases, and metabolic comorbidities is one of the major risk factors for delayed union and non-union formation.
Maximilian M Menger +9 more
doaj +1 more source
Bone Reports, 2021 Long-bone fracture is a common injury and its healing process at the fracture site involves several overlapping phases, including inflammation, migration of mesenchymal progenitors into the fracture site, endochondral ossification, angiogenesis and ...
Matthieu Bourgery +11 more
doaj +1 more source
Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway [PDF]
, 2020 We previously established that DNA methyltransferase 3b (Dnmt3b) is the sole Dnmt responsive to fracture repair and that Dnmt3b expression is induced in progenitor cells during fracture repair.
Abu-Amer, Yousef +8 more
core +1 more source
Novel skeletal effects of glucagon-like peptide-1 (GLP-1) receptor agonists [PDF]
, 2017 Type 2 diabetes mellitus (T2DM) leads to bone fragility and predisposes to increased risk of fracture, poor bone healing and other skeletal complications.
Chantal Chenu +4 more
core +5 more sources
Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures [PDF]
, 2013 Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Alt, Volker +16 more
core +2 more sources
THE EFFECT OF DENERVATION ON FRACTURE HEALING , AN EXPERIMENTAL STUDY ON RABBITS [PDF]
Basrah Journal of Surgery, 2014 THE EFFECT OF DENERVATION ON FRACTURE HEALING , AN EXPERIMENTAL STUDY ON RABBITS Thamer A Hamdan , Mubder A Mohammed Saeed & Abbas Salman Ismael Abstract Many studies suggested a relation between denervation and fracture healing either in positive or ...
THAMIR A. HAMDAN +2 more
doaj +1 more source
Administration of Tramadol or Buprenorphine via the drinking water for post-operative analgesia in a mouse-osteotomy model [PDF]
, 2019 Adequate analgesia is essential whenever pain might occur in animal experiments. Unfortunately, the selection of suitable analgesics for mice in bone-linked models is limited. Here, we evaluated two analgesics - Tramadol [0.1 mg/ml (Tlow) vs.
Buttgereit, Frank +7 more
core +1 more source