Results 1 to 10 of about 1,721,489 (338)
Single-Cell RNA Sequencing Reveals B Cells Are Important Regulators in Fracture Healing
Frontiers in Endocrinology, 2021 The bone marrow microenvironment is composed primarily of immune and stromal cells that play important roles in fracture healing. Although immune cells have been identified in mouse bone marrow, variations in their numbers and type during the fracture ...
Hao Zhang +12 more
doaj +2 more sources
Modulation of fracture healing by the transient accumulation of senescent cells
eLife, 2021 Senescent cells have detrimental effects across tissues with aging but may have beneficial effects on tissue repair, specifically on skin wound healing. However, the potential role of senescent cells in fracture healing has not been defined.
Dominik Saul +7 more
doaj +2 more sources
Osteoimmunology of Fracture Healing. [PDF]
Curr Osteoporos RepAbstract Purpose of Review The purpose of this review is to summarize what is known in the literature about the role inflammation plays during bone fracture healing. Bone fracture healing progresses through four distinct yet overlapping phases: formation of the hematoma, development of the cartilaginous callus ...
Molitoris KH, Huang M, Baht GS.
europepmc +3 more sources
Effects of Aging on Fracture Healing [PDF]
Current Osteoporosis Reports, 2017 This review summarizes research on the physiological changes that occur with aging and the resulting effects on fracture healing.Aging affects the inflammatory response during fracture healing through senescence of the immune response and increased systemic pro-inflammatory status.
T. Miclau +6 more
openaire +6 more sources
Effectiveness of Teriparatide on Fracture Healing: A Systematic Review and Meta-Analysis.
PLoS ONE, 2016 PurposeNowadays, the efficacy of teriparatide in treating osteoporosis was widely accepted, but the discussion about using teriparatide to enhance fracture healing hasn't come to an agreement.
Zhongju Shi +7 more
doaj +2 more sources
The effect of whole body vibration on fracture healing – a systematic review [PDF]
European Cells & Materials, 2017 This systematic review examines the efficacy and safety of whole body vibration (WBV) on fracture healing. A systematic literature search was conducted with relevant keywords in PubMed and Embase, independently, by two reviewers.
J Wang, KS Leung, SKH Chow, WH Cheung
doaj +2 more sources
The Science of Fracture Healing
Journal of Orthopaedic Trauma, 2005 Fracture healing is a unique repair process in which the events of endochondral and intramembranous bone formation follow a specific time sequence. There are many ways in which these events can be disrupted, leading to unsuccessful fracture healing. This article summarizes the series of cellular and molecular events that take place in the process of ...
Thomas A. Einhorn
openalex +4 more sources
The effect of favipiravir on fracture healing. [PDF]
Acta Orthop Traumatol TurcThe aim of this study was to evaluate the effects of favipiravir on fracture healing. Forty-eight female rats which had a femur fracture with intramedullary Kirschner wire fixation performed were divided into 6 groups; 2 control groups (C1, C2) and 4 experimental groups (F1, F2, F3, F4). The control groups (C1, C2) received physiological saline by oral
Sabır MA +3 more
europepmc +4 more sources
Advances in Animal Models for Studying Bone Fracture Healing
Bioengineering, 2023 Fracture is a common traumatic injury that is mostly caused by traffic accidents, falls, and falls from height. Fracture healing is a long-term and complex process, and the mode of repair and rate of healing are influenced by a variety of factors.
Hui Gao +3 more
semanticscholar +1 more source
Fracture Healing in the Setting of Endocrine Diseases, Aging, and Cellular Senescence.
Endocrine reviews, 2022 Over 2.1 million age-related fractures occur in the United States annually, resulting in an immense socioeconomic burden. Importantly, the age-related deterioration of bone structure is associated with impaired bone healing. Fracture healing is a dynamic
D. Saul, S. Khosla
semanticscholar +1 more source