Results 1 to 10 of about 1,593,826 (46)
Fracture Healing in the Setting of Endocrine Diseases, Aging, and Cellular Senescence.
Over 2.1 million age-related fractures occur in the United States annually, resulting in an immense socioeconomic burden. Importantly, the age-related deterioration of bone structure is associated with impaired bone healing. Fracture healing is a dynamic
D. Saul, S. Khosla
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The neuronal engagement of the peripheral nerve system plays a crucial role in regulating fracture healing, but how to modulate the neuronal activity to enhance fracture healing remains unexploited.
Jie Mi+16 more
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Significance Bone fracture represents a significant problem in public health. State-of-the-art clinical study demonstrated that by correlating the stimulation amplitude and frequency directly to dynamic locomotion, biofeedback electrostimulation therapy ...
Guang Yao+12 more
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As important players in cell-to-cell communication, exosomes (exo) are believed to play a similar role in promoting fracture healing. This study investigated whether exosomes derived from bone marrow mesenchymal stem cells (BMMSC-Exos) could improve ...
Lu Zhang+9 more
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Age‐related changes to macrophages are detrimental to fracture healing in mice
The elderly population suffers from higher rates of complications during fracture healing that result in increased morbidity and mortality. Inflammatory dysregulation is associated with increased age and is a contributing factor to the myriad of age ...
D. Clark+8 more
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Heterogeneity of murine periosteum progenitors involved in fracture healing
The periosteum is the major source of cells involved in fracture healing. We sought to characterize progenitor cells and their contribution to bone fracture healing. The periosteum is highly enriched for progenitor cells, including Sca1+ cells, CFU-F and
B. Matthews+7 more
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Exosomes, as important players in intercellular communication due to their ability to transfer certain molecules to target cells, are believed to take similar effects in promoting bone regeneration with their derived stem cells.
Yun-tong Zhang+7 more
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The Role of the Immune Cells in Fracture Healing
Purpose of reviewBone fracture healing is a complex physiological process relying on numerous cell types and signals. Inflammatory factors secreted by immune cells help to control recruitment, proliferation, differentiation, and activation of ...
G. Baht, Linda Vi, B. Alman
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Cellular biology of fracture healing
The biology of bone healing is a rapidly developing science. Advances in transgenic and gene‐targeted mice have enabled tissue and cell‐specific investigations of skeletal regeneration.
C. Bahney+8 more
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The Impact of Type 2 Diabetes on Bone Fracture Healing
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease known by the presence of elevated blood glucose levels. Nowadays, it is perceived as a worldwide epidemic, with a very high socioeconomic impact on public health.
C. Marín+4 more
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