Results 1 to 10 of about 1,743,760 (406)
Age-related changes to macrophages are detrimental to fracture healing in mice. [PDF]
Aging Cell, 2020 The elderly population suffers from higher rates of complications during fracture healing that result in increased morbidity and mortality. Inflammatory dysregulation is associated with increased age and is a contributing factor to the myriad of age ...
Brazina, Sloane +8 more
core +3 more sources
Gait Analysis to Monitor Fracture Healing of the Lower Leg [PDF]
Bioengineering, 2023 Fracture healing is typically monitored by infrequent radiographs. Radiographs come at the cost of radiation exposure and reflect fracture healing with a time lag due to delayed fracture mineralization following increases in stiffness.
Elke Warmerdam +3 more
doaj +3 more sources
Near-Infrared Spectroscopy Allows for Monitoring of Bone Fracture Healing via Changes in Oxygenation [PDF]
Journal of Functional BiomaterialsBone fractures are associated with hypoxia, but no longitudinal studies of perfusion measurements in human patients have been reported despite the clinical and research potential.
Cedric Nowicki, Bergita Ganse
doaj +2 more sources
Scope and Limits of Teriparatide Use in Delayed and Nonunions: A Case Series [PDF]
Clinics and Practice, 2021 Nonunion is known to occur in up to 10% of all bone fractures. Until recently, the treatment options considered in cases of delayed union and nonunion focused on revision surgery and improvement of local healing.
Petros Ismailidis +4 more
doaj +3 more sources
Computer simulation of fatigue under diametrical compression [PDF]
, 2006 We study the fatigue fracture of disordered materials by means of computer simulations of a discrete element model. We extend a two-dimensional fracture model to capture the microscopic mechanisms relevant for fatigue, and we simulate the diametric compression of a disc shape specimen under a constant external force.
Andrade Jr., J. S. +3 more
arxiv +5 more sources
Effectiveness of Teriparatide on Fracture Healing: A Systematic Review and Meta-Analysis. [PDF]
PLoS ONE, 2016 PURPOSE:Nowadays, the efficacy of teriparatide in treating osteoporosis was widely accepted, but the discussion about using teriparatide to enhance fracture healing hasn't come to an agreement.
Zhongju Shi +7 more
doaj +2 more sources
Cell Proliferation, 2019 Exosomes, as important players in intercellular communication due to their ability to transfer certain molecules to target cells, are believed to take similar effects in promoting bone regeneration with their derived stem cells.
Zichen Hao, Demeng Xia, Shuogui Xu
exaly +2 more sources
The biology of fracture healing. [PDF]
Injury, 2011 The biology of fracture healing is a complex biological process that follows specific regenerative patterns and involves changes in the expression of several thousand genes. Although there is still much to be learned to fully comprehend the pathways of bone regeneration, the over-all pathways of both the anatomical and biochemical events have been ...
R. Marsell, T. Einhorn
semanticscholar +4 more sources
Biomechanical Characteristics of Osteoporotic Fracture Healing in Ovariectomized Rats: A Systematic Review. [PDF]
PLoS ONE, 2016 Biomechanical tests are widely used in animal studies on osteoporotic fracture healing. However, the biomechanical recovery process is still unknown, leading to difficulty in choosing time points for biomechanical tests and in correctly assessing ...
Lin Chen +6 more
doaj +2 more sources
Exploring the role of OIP5-AS1 in the mechanisms of delayed fracture healing: functional insights and clinical implications [PDF]
Journal of Orthopaedic Surgery and ResearchObjective Fracture is a common traumatic disease and there is a risk of delayed healing after fracture occurs. This study aimed to explore the regulatory roles and clinical implications of OIP5-AS1 in delayed fracture healing.
Yusen Hu, Meini Cen, Yi Hu
doaj +2 more sources