Results 31 to 40 of about 1,721,489 (338)

Akkermansia muciniphila promotes type H vessel formation and bone fracture healing by reducing gut permeability and inflammation

open access: yesDisease Models & Mechanisms, 2020
Improving revascularization is one of the major measures in fracture treatment. Moderate local inflammation triggers angiogenesis, whereas systemic inflammation hampers angiogenesis.
Jiang-Hua Liu   +11 more
semanticscholar   +1 more source

Prognostic and therapeutic potential of microRNAs for fracture healing processes and non‐union fractures: A systematic review

open access: yesClinical and Translational Medicine, 2023
Background Approximately 10% of all bone fractures result in delayed fracture healing or non‐union; thus, the identification of biomarkers and prognostic factors is of great clinical interest. MicroRNAs (miRNAs) are known to be involved in the regulation
Franziska Lioba Breulmann   +6 more
doaj   +1 more source

Near-Infrared Spectroscopy Allows for Monitoring of Bone Fracture Healing via Changes in Oxygenation

open access: yesJournal of Functional Biomaterials
Bone fractures are associated with hypoxia, but no longitudinal studies of perfusion measurements in human patients have been reported despite the clinical and research potential.
Cedric Nowicki, Bergita Ganse
doaj   +1 more source

Genetic polymorphisms of NOS2 and predisposition to fracture non-union: A case control study based on Han Chinese population. [PDF]

open access: yesPLoS ONE, 2018
A non-union, especially atrophic non-unions, is a permanent failure of healing following a fracture and can be difficult to treat. Approximately 5-10% of fractures will result in a non-union during the healing process.
Wei Huang   +5 more
doaj   +1 more source

Scope and Limits of Teriparatide Use in Delayed and Nonunions: A Case Series

open access: yesClinics and Practice, 2021
Nonunion is known to occur in up to 10% of all bone fractures. Until recently, the treatment options considered in cases of delayed union and nonunion focused on revision surgery and improvement of local healing.
Petros Ismailidis   +4 more
doaj   +1 more source

Exosomes from human umbilical cord mesenchymal stem cells enhance fracture healing through HIF‐1α‐mediated promotion of angiogenesis in a rat model of stabilized fracture

open access: yesCell Proliferation, 2019
Exosomes, as important players in intercellular communication due to their ability to transfer certain molecules to target cells, are believed to take similar effects in promoting bone regeneration with their derived stem cells.
Yuntong Zhang   +7 more
semanticscholar   +1 more source

Correlation of serum PTH level and fracture healing speed in elderly patients with hip fracture

open access: yesJournal of Orthopaedic Surgery and Research, 2019
Purpose To access serum parathyroid hormone (PTH) level in elderly patients with hip fracture in relation to fracture healing outcomes. Methods This study included 90 elderly male patients with hip fracture and they were defined as the hip fracture group,
Zhao-Nan Ban   +5 more
doaj   +1 more source

Animal models for studying metaphyseal bone fracture healing [PDF]

open access: yesEuropean Cells & Materials, 2020
An estimated 2 million osteoporotic fractures occur annually in the US, resulting in a dramatic reduction in quality of life for affected patients and a high economic burden for society.
M Haffner-Luntzer, A Ignatius
doaj   +1 more source

The walking surface influences vertical ground reaction force and centre of pressure data obtained with pressure-sensing insoles

open access: yesFrontiers in Digital Health
BackgroundGait can be continuously monitored via vertical ground reaction force (VGRF) and centre of pressure (COP) measurement with pressure-sensing insoles.
Elke Warmerdam   +6 more
doaj   +1 more source

Cellular biology of fracture healing

open access: yesJournal of Orthopaedic Research, 2018
The biology of bone healing is a rapidly developing science. Advances in transgenic and gene‐targeted mice have enabled tissue and cell‐specific investigations of skeletal regeneration.
C. Bahney   +8 more
semanticscholar   +1 more source

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