Results 31 to 40 of about 1,704,060 (353)

Prognostic and therapeutic potential of microRNAs for fracture healing processes and non‐union fractures: A systematic review

open access: yesClinical and Translational Medicine, 2023
Background Approximately 10% of all bone fractures result in delayed fracture healing or non‐union; thus, the identification of biomarkers and prognostic factors is of great clinical interest. MicroRNAs (miRNAs) are known to be involved in the regulation
Franziska Lioba Breulmann   +6 more
doaj   +1 more source

Genetic polymorphisms of NOS2 and predisposition to fracture non-union: A case control study based on Han Chinese population. [PDF]

open access: yesPLoS ONE, 2018
A non-union, especially atrophic non-unions, is a permanent failure of healing following a fracture and can be difficult to treat. Approximately 5-10% of fractures will result in a non-union during the healing process.
Wei Huang   +5 more
doaj   +1 more source

Intact Glucocorticoid Receptor Dimerization Is Deleterious in Trauma-Induced Impaired Fracture Healing

open access: yesFrontiers in Immunology, 2021
Following severe trauma, fracture healing is impaired because of overwhelming systemic and local inflammation. Glucocorticoids (GCs), acting via the glucocorticoid receptor (GR), influence fracture healing by modulating the trauma-induced immune response.
Yasmine Hachemi   +7 more
doaj   +1 more source

Correlation of serum PTH level and fracture healing speed in elderly patients with hip fracture

open access: yesJournal of Orthopaedic Surgery and Research, 2019
Purpose To access serum parathyroid hormone (PTH) level in elderly patients with hip fracture in relation to fracture healing outcomes. Methods This study included 90 elderly male patients with hip fracture and they were defined as the hip fracture group,
Zhao-Nan Ban   +5 more
doaj   +1 more source

Cellular biology of fracture healing

open access: yesJournal of Orthopaedic Research, 2018
The biology of bone healing is a rapidly developing science. Advances in transgenic and gene‐targeted mice have enabled tissue and cell‐specific investigations of skeletal regeneration.
C. Bahney   +8 more
semanticscholar   +1 more source

Timing of osteoporosis therapies following fracture: the current status

open access: yesTherapeutic Advances in Endocrinology and Metabolism, 2022
In most patients, osteoporosis is diagnosed only after the occurrence of the first fragility fracture. It is of utmost importance to start osteoporosis medications immediately in these patients to prevent future fractures and also to reduce associated ...
Rajan Palui   +4 more
doaj   +1 more source

Scope and Limits of Teriparatide Use in Delayed and Nonunions: A Case Series

open access: yesClinics and Practice, 2021
Nonunion is known to occur in up to 10% of all bone fractures. Until recently, the treatment options considered in cases of delayed union and nonunion focused on revision surgery and improvement of local healing.
Petros Ismailidis   +4 more
doaj   +1 more source

The Role of the Immune Cells in Fracture Healing

open access: yesCurrent Osteoporosis Reports, 2018
Purpose of reviewBone fracture healing is a complex physiological process relying on numerous cell types and signals. Inflammatory factors secreted by immune cells help to control recruitment, proliferation, differentiation, and activation of ...
G. Baht, Linda Vi, B. Alman
semanticscholar   +1 more source

The walking surface influences vertical ground reaction force and centre of pressure data obtained with pressure-sensing insoles

open access: yesFrontiers in Digital Health
BackgroundGait can be continuously monitored via vertical ground reaction force (VGRF) and centre of pressure (COP) measurement with pressure-sensing insoles.
Elke Warmerdam   +6 more
doaj   +1 more source

The Impact of Type 2 Diabetes on Bone Fracture Healing

open access: yesFrontiers in Endocrinology, 2018
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease known by the presence of elevated blood glucose levels. Nowadays, it is perceived as a worldwide epidemic, with a very high socioeconomic impact on public health.
C. Marín   +4 more
semanticscholar   +1 more source

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