Results 71 to 80 of about 54,055 (308)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
MATEC Web of Conferences, 2019 Fragility curves express the seismic vulnerability of bridge piers for different damage states at various earthquake intensities. A fragility curve typically gives a physical understanding of repair costs and functionally levels of a bridge pier.
Ahmad Nursafarina +2 more
doaj +1 more source
Tecnología y ciencias del agua, 2020 Hardfill dams are comprised of cemented granular materials gathered directly from the river bed or its surroundings, or which are by-product of the dam excavation.
Grissel Hurtado-López +1 more
doaj +1 more source
Evaluation of analytical methodologies to derive vulnerability functions [PDF]
, 2012 The recognition of fragility functions as a fundamental tool in seismic risk assessment has led to the development of more and more complex and elaborate procedures for their computation.
Crowley, H. +4 more
core +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Flood fragility analysis for bridges with multiple failure modes [PDF]
, 2017 Bridges are one of the most important infrastructure systems that provide public and economic bases for humankind. It is also widely known that bridges are exposed to a variety of flood-related risk factors such as bridge scour, structural deterioration,
American Association of State Highway and Transportation Officials (AASHTO) +19 more
core +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Fragility of Highway Embankments Exposed to Permanent Deformations Due to Underlying Fault Rupture
GeosciencesSeismic risk expresses the expected degree of damage and loss following a catastrophic event. An efficient tool for assessing the seismic risk of embankments is fragility curves.
Eleni Petala, Nikolaos Klimis
doaj +1 more source
Seismic risk analysis of multistory reinforced concrete structures in Saudi Arabia
Case Studies in Construction Materials, 2018 In this research, analytical fragility curves for typical mid-rise plane reinforced concrete moment-resisting frames in Kingdom of Saudi Arabia, KSA, which is considered low-seismicity area, are presented.
Yasser E. Ibrahim
doaj +1 more source
, 2001 Glass is a microscopically disordered, solid form of matter that results when a fluid is cooled or compressed in such a fashion that it does not crystallise.
A Heuer +28 more
core +1 more source