Results 71 to 80 of about 2,213,618 (351)
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Fragility and Vulnerability Analysis of an RC Building with the Application of Nonlinear Analysis
Buildings, 2021 In this paper, the seismic response of a five-story reinforced concrete (RC) frame system building is analysed through fragility analysis. The structure is designed in accordance with structural Eurocodes EN1990, EN1991, EN1992 and EN1998, as a high ...
Radomir Folić, Miloš Čokić
doaj +1 more source
Tsunami fragility curves of a RC structure through different analytical methods [PDF]
, 2016 Recent tsunami events have stimulated research activity into tsunami fragility functions which have been largely based on empirical data. However, empirical fragility functions are biased because the influence of earthquake and tsunami damage are ...
Eames, Ian +3 more
core
Nonlinear dynamic analysis and seismic fragility assessment of a corrosion damaged integral bridge [PDF]
, 2016 Purpose In this paper the impact of corrosion of reinforcing steel in RC columns on the seismic performance of a multi-span concrete integral bridge is explored.
Alexander, Nicholas A +6 more
core +2 more sources
Empirical fragility curves for Italian residential RC buildings
Bulletin of Earthquake Engineering, 2020 In this paper, empirical fragility curves for reinforced concrete buildings are derived, based on post-earthquake damage data collected in the aftermath of earthquakes occurred in Italy in the period 1976–2012.
A. Rosti +6 more
semanticscholar +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
THE DISTRIBUTION CURVE OF ERYTHROCYTE FRAGILITY [PDF]
Blood, 1949 Abstract 1. A simple method of representing erythrocyte fragility as a distribution curve of actual cellular fragility is described. 2. The importance of deciding the form of a distribution before using summarizing statistics is emphasized. 3.
openaire +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Tecnología y ciencias del agua, 2020 Hardfill dams are comprised of cemented granular materials gathered directly from the river bed or its surroundings, or which are by-product of the dam excavation.
Grissel Hurtado-López +1 more
doaj +1 more source
Reliability Analysis of Response-Controlled Buildings Using Fragility Curves
Applied Sciences, 2022 The number of buildings with passive control systems is steadily growing worldwide. For this reason, this study focuses on the reliability analysis of these systems employing fragility curves.
Ahmad Khalid Karimi +2 more
doaj +1 more source