Results 101 to 110 of about 121,391 (276)

Modulation of Dengue/Zika Virus Pathogenicity by Antibody-Dependent Enhancement and Strategies to Protect Against Enhancement in Zika Virus Infection

Frontiers in Immunology, 2018
Antibody-dependent enhancement (ADE) is a phenomenon in which preexisting poorly neutralizing antibodies leads to enhanced infection. It is a serious concern with mosquito-borne flaviviruses such as Dengue virus (DENV) and Zika virus (ZIKV).
Rekha Khandia, Ashok Munjal, Kuldeep Dhama, Kumaragurubaran Karthik, Ruchi Tiwari, Yashpal Singh Malik, Raj Kumar Singh, Wanpen Chaicumpa   +7 more
doaj   +1 more source

Expression, Purification, and Biophysical Characterization of a Secreted Anthrax Decoy Fusion Protein in Nicotiana benthamiana. [PDF]

, 2017
Anthrax toxin receptor-mediated drug development for blocking anthrax toxin action has received much attention in recent decades. In this study, we produced a secreted anthrax decoy fusion protein comprised of a portion of the human capillary ...
Dandekar, Abhaya M, Duhra-Gill, Sifti, Kailemia, Muchena J, Karuppanan, Kalimuthu, Lebrilla, Carlito B, McDonald, Karen A, Nandi, Somen, Phu, My L, Rodriguez, Raymond L   +8 more
core   +2 more sources

Plant-Derived Anti-Human Epidermal Growth Factor Receptor 2 Antibody Suppresses Trastuzumab-Resistant Breast Cancer with Enhanced Nanoscale Binding

ACS Nano
Traditional monoclonal antibodies such as Trastuzumab encounter limitations when treating Human Epidermal Growth Factor Receptor 2 (HER2)-positive breast cancer, particularly in cases that develop resistance. This study introduces plant-derived anti-HER2
Chanyong Park, Kibum Kim, Yerin Kim, Rong Zhu, L. Hain, Hannah Seferovic, Min-Hyeok Kim, Hyun Joo Woo, Hyunju Hwang, Seung Ho Lee, Sangmin Kim, Jeong Eon Lee, Peter Hinterdorfer, Kisung Ko, Sungsu Park, Y. Oh   +15 more
semanticscholar   +1 more source

Deciphering the Interplay Between Wetting and Chemo‐Mechanical Fracture in Lithium‐Ion Battery Cathode Materials

Advanced Functional Materials, EarlyView.
The fundamental intricate couplings between electrolyte wetting and fracture evolution are investigated in large single‐crystal V2O5 samples using both experimental techniques and simulations. Both approaches reveal consistent fracture patterns and lithium distribution concentration maps influenced by the wetting mechanism.
Wan‐Xin Chen, Luis J. Carrillo, Arnab Maji, Xiang‐Long Peng, Joseph Handy, Sarbajit Banerjee, Bai‐Xiang Xu   +6 more
wiley   +1 more source

Actin polymerization stabilizes α4β1 integrin anchors that mediate monocyte adhesion [PDF]

, 2012
Leukocytes arrested on inflamed endothelium via integrins are subjected to force imparted by flowing blood. How leukocytes respond to this force and resist detachment is poorly understood.
Adrianet Puig Cano, Alon, Alon, Alon, Arthur, Bos, Botelho, Brakebusch, Butcher, Campbell, Chan, Chen, Choquet, Christopher A. McCulloch, Constantin, Coughlin, Coughlin, Critchley, de Bruyn, Ferrandi, Fukuyama, Genevieve Digby, Ghandour, Hall, Han, Hartwig, Hartwig, Heit, Henry Becker, Howard, Hyduk, Hyduk, Hyduk, Hynes, Jacob Rullo, Janice C. Wong, John Hartwig, Katsumi, Kim, Kortholt, Kucik, Ley, Makino, Manser, Matthews, Myron I. Cybulsky, Nebe, Pamma D. Arora, Pollard, Ramachandran, Ridley, Ridley, Ridley, Riedl, Sadhu, Sasaki, Sawada, Sawada, Schmidtke, Sharon J. Hyduk, Shimonaka, Smith, Srinivasan, Sundd, Suzuma, Tzima, Tzima, van Kooyk, Vanhaesebroeck, Vicente-Manzanares, Wang, Yu, Yu   +72 more
core   +1 more source

Emergent Spin‐Glass Behavior in an Iron(II)‐Based Metal–Organic Framework Glass

Advanced Functional Materials, EarlyView.
A one‐pot, solvent‐free synthesis yields an Fe2+‐based metal‐organic framework (MOF) glass featuring a continuous random network structure. The material exhibits spin‐glass freezing at 14 K, driven by topological‐disorder and short‐range magnetic frustration, showcasing the potential of MOF glasses as a plattform for cooperative magnetic phenomena in ...
Chinmoy Das, Soma Salamon, Joachim Landers, Jan‐Benedikt Weiß, Wen‐Long Xue, Pascal Kolodzeiski, Roman Pallach, Heiko Wende, Sebastian Henke   +8 more
wiley   +1 more source

Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation [PDF]

, 2017
Joint modeling of a number of phenotypes using multivariate methods has often been neglected in genome-wide association studies and if used, replication has not been sought. Modern omics technologies allow characterization of functional phenomena using a
Aulchenko, Yurii S., Hayward, Caroline, Klarić, Lucija, Lauc, Gordan, Mangino, Massimo, Ning, Zheng, Polasek, Ozren, Pučić-Baković, Maja, Rudan, Igor, Sharapov, Sodbo, Shen, Xia, Spector, Tim D, Trbojević-Akmačić, Irena, Wilson, James F., Wu, Di   +14 more
core   +3 more sources

An In Situ Study of the Topochemical Transformation of Hybrid Layered Hydroxides Into Metallic Nanocomposites

Advanced Functional Materials, EarlyView.
Herein, the topochemical transformation of cobalt‐based layered hydroxides into nanocomposites is investigated using advanced real‐time characterization techniques combined with thermogravimetric analysis. The study reveals how interlayer carboxylic acids direct the transformation pathway, highlighting the role of carbon content and anion length. These
Camilo Jaramillo‐Hernández, Víctor Oestreicher, Martin Mizrahi, Cristián Huck‐Iriart, Christian Dolle, Gonzalo Abellán   +5 more
wiley   +1 more source

Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery

Advanced Healthcare Materials, EarlyView.
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo, Daniel Lozano, Antonio J. Salinas, María Vallet‐Regí   +3 more
wiley   +1 more source

Biomimetic Mineralization of Keratin Scaffolds for Enamel Regeneration

Advanced Healthcare Materials, EarlyView.
Keratin‐based films guide biomimetic enamel remineralization by promoting organized hydroxyapatite growth under physiological conditions. Advanced biophysical characterization confirms keratin's structural adaptability and mineral ions‐binding affinity, supporting mineral nucleation and hierarchical crystal assembly. This study establishes keratin as a
Sara Gamea, Elham Radvar, Dimitra Athanasiadou, Ryan Lee Chan, Giacomo De Sero, Ecaterina Ware, Sunie Kundi, Avir Patel, Shwan Horamee, Shuaib Hadadi, Mads Carlsen, Leanne Allison, Roland Fleck, Ka Lung Andrew Chan, Avijit Banerjee, Nicola Pugno, Marianne Liebi, Paul T Sharpe, Karina Carneiro, Sherif Elsharkawy   +19 more
wiley   +1 more source