Results 101 to 110 of about 122,949 (273)

Glycosimilarity assessment of biotherapeutics 1: quantitative comparison of the N-glycosylation of the innovator and a biosimilar version of etanercept [PDF]

, 2018
K
Borza, Beáta, Guttman, András, Hajba, László, Szekrényes, Ákos, Szigeti, Márton   +4 more
core  

Effects of allergic diseases and age on the composition of serum IgG glycome in children [PDF]

, 2016
Acknowledgements Glycan analysis was partly supported by European Commission GlycoBioM (contract #259869), IBD-BIOM (contract #305479), HighGlycan (contract #278535), MIMOmics (contract #305280), HTP-GlycoMet (contract #324400) and IntegraLife (contract #
Bakovic, Maja Pucic, Banic, Ivana, Devereux, Graham, Gospic, Adrijana Miletic, Lauc, Gordan, Lokas, Sandra Bulat, Perica, Marija, Pezer, Marija, Plavec, Davor, Razdorov, Genadij, Stambuk, Jerko, Turkalj, Mirjana, Ugrina, Ivo, Vecenaj, Ana, Vuckovic, Frano, Zivkovic, Jelena   +15 more
core   +1 more source

Plant-Derived Anti-Human Epidermal Growth Factor Receptor 2 Antibody Suppresses Trastuzumab-Resistant Breast Cancer with Enhanced Nanoscale Binding

ACS Nano
Traditional monoclonal antibodies such as Trastuzumab encounter limitations when treating Human Epidermal Growth Factor Receptor 2 (HER2)-positive breast cancer, particularly in cases that develop resistance. This study introduces plant-derived anti-HER2
Chanyong Park, Kibum Kim, Yerin Kim, Rong Zhu, L. Hain, Hannah Seferovic, Min-Hyeok Kim, Hyun Joo Woo, Hyunju Hwang, Seung Ho Lee, Sangmin Kim, Jeong Eon Lee, Peter Hinterdorfer, Kisung Ko, Sungsu Park, Y. Oh   +15 more
semanticscholar   +1 more source

Role of Histidine‐Containing Peptoids in Accelerating the Kinetics of Calcite Growth

Advanced Functional Materials, EarlyView.
Amphiphilic histidine‐containing peptoids mimic carbonic anhydrase (CA) to accelerate calcite step growth. In the presence of Zn2+, they promote the deprotonation of HCO3−, the desolvation of Ca2+, and the reorganization of interfacial hydration layers, thereby reducing the activation barrier for calcite growth.
Mingyi Zhang, Ying Chen, Chenyang Shi, Progyateg Chakma, James J. De Yoreo, Chun‐Long Chen   +5 more
wiley   +1 more source

Engineering of a recombinant fab antibody fragment against cortisol [PDF]

, 2013
The paper dwells upon the molecular cloning of genes coding the structure of mouse immunoglobulins, which can specifically bind steroid hormone cortisol.
Dormeshkin, D. O., Gilep, A. A., Ivashkevich, I. G., Leontiev, V. N.   +3 more
core  

Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation [PDF]

, 2017
Joint modeling of a number of phenotypes using multivariate methods has often been neglected in genome-wide association studies and if used, replication has not been sought. Modern omics technologies allow characterization of functional phenomena using a
Aulchenko, Yurii S., Hayward, Caroline, Klarić, Lucija, Lauc, Gordan, Mangino, Massimo, Ning, Zheng, Polasek, Ozren, Pučić-Baković, Maja, Rudan, Igor, Sharapov, Sodbo, Shen, Xia, Spector, Tim D, Trbojević-Akmačić, Irena, Wilson, James F., Wu, Di   +14 more
core   +3 more sources

Upcycling of Disposable Face Masks into Water‐Resistant and Flame Retardant Foams

Advanced Functional Materials, EarlyView.
Disposable mask waste is upcycled into lightweight polypropylene‐based foams with tunable porosity and composite architectures reinforced by ear‐loop fibers. The sustainable solvent‐based process enables upcycling rates of 91% and solvent recovery of >90%.
Jingjing Pan, Erlantz Lizundia, Hao Jia, Lennart Bergström   +3 more
wiley   +1 more source

Fc Engineering for Developing Therapeutic Bispecific Antibodies and Novel Scaffolds [PDF]

, 2017
Therapeutic monoclonal antibodies have become molecules of choice to treat autoimmune disorders, inflammatory diseases, and cancer. Moreover, bispecific/multispecific antibodies that target more than one antigen or epitope on a target cell or recruit ...
Abhishek Saxena, Donghui Wu, Hongyan Liu, Sachdev S. Sidhu   +3 more
core   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Identification of a novel mechanism of action of bovine IgG antibodies specific for Staphylococcus aureus

Veterinary Research, 2018
Staphylococcus aureus is a major pathogen that causes subclinical mastitis associated with huge economic losses to the dairy industry. A few vaccines for bovine mastitis are available, and they are expected to induce the production of S.
Mutsumi Furukawa, Hiroshi Yoneyama, Eiji Hata, Hidetomo Iwano, Hidetoshi Higuchi, Tasuke Ando, Mika Sato, Tomohito Hayashi, Yoshio Kiku, Yuya Nagasawa, Kanae Niimi, Katsuki Usami, Kumiko Ito, Kouichi Watanabe, Tomonori Nochi, Hisashi Aso   +15 more
doaj   +1 more source